BindingDB logo
myBDB logout

Patent code US9346821

Compile Data Set for Download or QSAR
Found 66 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Trypsin-1


(Homo sapiens (human))
BDBM234238
PNG
(US9346821, A-6)
Show SMILES NC(=N)c1ccc2cc(OC(=O)c3ccc(CN4CCC[C@@H]4C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)o3)ccc2c1
Show InChI InChI=1S/C25H26N4O9S/c26-22(27)16-4-3-15-11-17(6-5-14(15)10-16)38-25(33)21-8-7-18(37-21)12-29-9-1-2-20(29)23(30)28-19(24(31)32)13-39(34,35)36/h3-8,10-11,19-20H,1-2,9,12-13H2,(H3,26,27)(H,28,30)(H,31,32)(H,34,35,36)/t19-,20+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.0800n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234250
PNG
(US9346821, B-20)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CSC[C@H]3C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C21H21FN4O7S2/c22-12-5-10(18(23)24)1-3-15(12)33-21(32)16-4-2-11(35-16)7-26-9-34-8-14(26)19(29)25-13(20(30)31)6-17(27)28/h1-5,13-14H,6-9H2,(H3,23,24)(H,25,29)(H,27,28)(H,30,31)/t13-,14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.150n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234247
PNG
(US9346821, B-14)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C21H23FN4O8S2/c22-13-8-11(18(23)24)3-5-16(13)34-21(30)17-6-4-12(35-17)9-26-7-1-2-15(26)19(27)25-14(20(28)29)10-36(31,32)33/h3-6,8,14-15H,1-2,7,9-10H2,(H3,23,24)(H,25,27)(H,28,29)(H,31,32,33)/t14-,15+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.190n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234266
PNG
(US9346821, B-55)
Show SMILES NC(=N)c1ccc(OC(=O)c2cc3CCN(Cc3s2)C(=O)N[C@@H](CC(O)=O)C(O)=O)c(F)c1
Show InChI InChI=1S/C20H19FN4O7S/c21-11-5-10(17(22)23)1-2-13(11)32-19(30)14-6-9-3-4-25(8-15(9)33-14)20(31)24-12(18(28)29)7-16(26)27/h1-2,5-6,12H,3-4,7-8H2,(H3,22,23)(H,24,31)(H,26,27)(H,28,29)/t12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.200n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234250
PNG
(US9346821, B-20)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CSC[C@H]3C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C21H21FN4O7S2/c22-12-5-10(18(23)24)1-3-15(12)33-21(32)16-4-2-11(35-16)7-26-9-34-8-14(26)19(29)25-13(20(30)31)6-17(27)28/h1-5,13-14H,6-9H2,(H3,23,24)(H,25,29)(H,27,28)(H,30,31)/t13-,14-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.210n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234266
PNG
(US9346821, B-55)
Show SMILES NC(=N)c1ccc(OC(=O)c2cc3CCN(Cc3s2)C(=O)N[C@@H](CC(O)=O)C(O)=O)c(F)c1
Show InChI InChI=1S/C20H19FN4O7S/c21-11-5-10(17(22)23)1-2-13(11)32-19(30)14-6-9-3-4-25(8-15(9)33-14)20(31)24-12(18(28)29)7-16(26)27/h1-2,5-6,12H,3-4,7-8H2,(H3,22,23)(H,24,31)(H,26,27)(H,28,29)/t12-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.240n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234237
PNG
(US9346821, A-5)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)o2)cc1
Show InChI InChI=1S/C21H24N4O9S/c22-18(23)12-3-5-13(6-4-12)34-21(29)17-8-7-14(33-17)10-25-9-1-2-16(25)19(26)24-15(20(27)28)11-35(30,31)32/h3-8,15-16H,1-2,9-11H2,(H3,22,23)(H,24,26)(H,27,28)(H,30,31,32)/t15-,16+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.240n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234243
PNG
(US9346821, B-10)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C21H23FN4O8S2/c22-13-8-11(18(23)24)3-5-16(13)34-21(30)17-6-4-12(35-17)9-26-7-1-2-15(26)19(27)25-14(20(28)29)10-36(31,32)33/h3-6,8,14-15H,1-2,7,9-10H2,(H3,23,24)(H,25,27)(H,28,29)(H,31,32,33)/t14-,15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.240n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234247
PNG
(US9346821, B-14)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C21H23FN4O8S2/c22-13-8-11(18(23)24)3-5-16(13)34-21(30)17-6-4-12(35-17)9-26-7-1-2-15(26)19(27)25-14(20(28)29)10-36(31,32)33/h3-6,8,14-15H,1-2,7,9-10H2,(H3,23,24)(H,25,27)(H,28,29)(H,31,32,33)/t14-,15+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.240n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234243
PNG
(US9346821, B-10)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C21H23FN4O8S2/c22-13-8-11(18(23)24)3-5-16(13)34-21(30)17-6-4-12(35-17)9-26-7-1-2-15(26)19(27)25-14(20(28)29)10-36(31,32)33/h3-6,8,14-15H,1-2,7,9-10H2,(H3,23,24)(H,25,27)(H,28,29)(H,31,32,33)/t14-,15-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.25n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234246
PNG
(US9346821, B-13)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C22H23FN4O7S/c23-13-8-11(19(24)25)3-5-16(13)34-22(33)17-6-4-12(35-17)10-27-7-1-2-15(27)20(30)26-14(21(31)32)9-18(28)29/h3-6,8,14-15H,1-2,7,9-10H2,(H3,24,25)(H,26,30)(H,28,29)(H,31,32)/t14-,15+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.290n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234265
PNG
(US9346821, B-47)
Show SMILES CC(C)N(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C21H23FN4O7S/c1-10(2)26(21(32)25-14(19(29)30)8-17(27)28)9-12-4-6-16(34-12)20(31)33-15-5-3-11(18(23)24)7-13(15)22/h3-7,10,14H,8-9H2,1-2H3,(H3,23,24)(H,25,32)(H,27,28)(H,29,30)/t14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.330n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234264
PNG
(US9346821, B-46)
Show SMILES CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C19H19FN4O7S/c1-24(19(30)23-12(17(27)28)7-15(25)26)8-10-3-5-14(32-10)18(29)31-13-4-2-9(16(21)22)6-11(13)20/h2-6,12H,7-8H2,1H3,(H3,21,22)(H,23,30)(H,25,26)(H,27,28)/t12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.380n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234253
PNG
(US9346821, B-26)
Show SMILES CC(C)[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C24H29FN4O7S/c1-12(2)20(22(32)28-16(23(33)34)6-9-19(30)31)29(3)11-14-5-8-18(37-14)24(35)36-17-7-4-13(21(26)27)10-15(17)25/h4-5,7-8,10,12,16,20H,6,9,11H2,1-3H3,(H3,26,27)(H,28,32)(H,30,31)(H,33,34)/t16-,20-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.380n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234255
PNG
(US9346821, B-29)
Show SMILES CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C28H29FN4O7S/c1-33(15-18-8-11-23(41-18)28(39)40-22-10-7-17(25(30)31)14-19(22)29)21(13-16-5-3-2-4-6-16)26(36)32-20(27(37)38)9-12-24(34)35/h2-8,10-11,14,20-21H,9,12-13,15H2,1H3,(H3,30,31)(H,32,36)(H,34,35)(H,37,38)/t20-,21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.380n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234242
PNG
(US9346821, A-21)
Show SMILES CC(C)N(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C21H24N4O8/c1-11(2)25(21(31)24-15(19(28)29)9-17(26)27)10-14-7-8-16(32-14)20(30)33-13-5-3-12(4-6-13)18(22)23/h3-8,11,15H,9-10H2,1-2H3,(H3,22,23)(H,24,31)(H,26,27)(H,28,29)/t15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.380n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234251
PNG
(US9346821, B-21)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CSC[C@H]3C(=O)N(CC=C)CC(O)=O)s2)c(F)c1
Show InChI InChI=1S/C22H23FN4O5S2/c1-2-7-26(10-19(28)29)21(30)16-11-33-12-27(16)9-14-4-6-18(34-14)22(31)32-17-5-3-13(20(24)25)8-15(17)23/h2-6,8,16H,1,7,9-12H2,(H3,24,25)(H,28,29)/t16-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.380n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234269
PNG
(US9346821, B-60)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N(CCC(O)=O)CC(O)=O)s2)c(F)c1
Show InChI InChI=1S/C23H25FN4O7S/c24-15-10-13(21(25)26)3-5-17(15)35-23(34)18-6-4-14(36-18)11-27-8-1-2-16(27)22(33)28(12-20(31)32)9-7-19(29)30/h3-6,10,16H,1-2,7-9,11-12H2,(H3,25,26)(H,29,30)(H,31,32)/t16-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.420n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234246
PNG
(US9346821, B-13)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C22H23FN4O7S/c23-13-8-11(19(24)25)3-5-16(13)34-22(33)17-6-4-12(35-17)10-27-7-1-2-15(27)20(30)26-14(21(31)32)9-18(28)29/h3-6,8,14-15H,1-2,7,9-10H2,(H3,24,25)(H,26,30)(H,28,29)(H,31,32)/t14-,15+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.430n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234267
PNG
(US9346821, B-56)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CC=C)CC(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C24H25FN4O8S/c1-2-9-29(12-19(30)28-16(23(34)35)11-21(32)33)20(31)8-5-14-4-7-18(38-14)24(36)37-17-6-3-13(22(26)27)10-15(17)25/h2-4,6-7,10,16H,1,5,8-9,11-12H2,(H3,26,27)(H,28,30)(H,32,33)(H,34,35)/t16-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.430n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234249
PNG
(US9346821, B-18)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCCC[C@H]3C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C23H25FN4O7S/c24-14-9-12(20(25)26)4-6-17(14)35-23(34)18-7-5-13(36-18)11-28-8-2-1-3-16(28)21(31)27-15(22(32)33)10-19(29)30/h4-7,9,15-16H,1-3,8,10-11H2,(H3,25,26)(H,27,31)(H,29,30)(H,32,33)/t15-,16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.440n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234252
PNG
(US9346821, B-23)
Show SMILES CC(C)[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C23H27FN4O7S/c1-11(2)19(21(31)27-15(22(32)33)9-18(29)30)28(3)10-13-5-7-17(36-13)23(34)35-16-6-4-12(20(25)26)8-14(16)24/h4-8,11,15,19H,9-10H2,1-3H3,(H3,25,26)(H,27,31)(H,29,30)(H,32,33)/t15-,19-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.440n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234240
PNG
(US9346821, A-14)
Show SMILES CC(C)[C@H](N(C)Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C23H28N4O8/c1-12(2)19(21(30)26-16(22(31)32)10-18(28)29)27(3)11-15-8-9-17(34-15)23(33)35-14-6-4-13(5-7-14)20(24)25/h4-9,12,16,19H,10-11H2,1-3H3,(H3,24,25)(H,26,30)(H,28,29)(H,31,32)/t16-,19-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.450n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234248
PNG
(US9346821, B-15)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C22H23FN4O7S/c23-13-8-11(19(24)25)3-5-16(13)34-22(33)17-6-4-12(35-17)10-27-7-1-2-15(27)20(30)26-14(21(31)32)9-18(28)29/h3-6,8,14-15H,1-2,7,9-10H2,(H3,24,25)(H,26,30)(H,28,29)(H,31,32)/t14-,15-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.520n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234269
PNG
(US9346821, B-60)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N(CCC(O)=O)CC(O)=O)s2)c(F)c1
Show InChI InChI=1S/C23H25FN4O7S/c24-15-10-13(21(25)26)3-5-17(15)35-23(34)18-6-4-14(36-18)11-27-8-1-2-16(27)22(33)28(12-20(31)32)9-7-19(29)30/h3-6,10,16H,1-2,7-9,11-12H2,(H3,25,26)(H,29,30)(H,31,32)/t16-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.530n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234257
PNG
(US9346821, B-35)
Show SMILES CC(C)C[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C24H29FN4O7S/c1-12(2)8-17(22(32)28-16(23(33)34)10-20(30)31)29(3)11-14-5-7-19(37-14)24(35)36-18-6-4-13(21(26)27)9-15(18)25/h4-7,9,12,16-17H,8,10-11H2,1-3H3,(H3,26,27)(H,28,32)(H,30,31)(H,33,34)/t16-,17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.530n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234241
PNG
(US9346821, A-20)
Show SMILES CN(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C19H20N4O8/c1-23(19(29)22-13(17(26)27)8-15(24)25)9-12-6-7-14(30-12)18(28)31-11-4-2-10(3-5-11)16(20)21/h2-7,13H,8-9H2,1H3,(H3,20,21)(H,22,29)(H,24,25)(H,26,27)/t13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.540n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234240
PNG
(US9346821, A-14)
Show SMILES CC(C)[C@H](N(C)Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C23H28N4O8/c1-12(2)19(21(30)26-16(22(31)32)10-18(28)29)27(3)11-15-8-9-17(34-15)23(33)35-14-6-4-13(5-7-14)20(24)25/h4-9,12,16,19H,10-11H2,1-3H3,(H3,24,25)(H,26,30)(H,28,29)(H,31,32)/t16-,19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.560n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234262
PNG
(US9346821, B-43)
Show SMILES NC(=N)c1ccc(OC(=O)c2cc3CCN(CC(O)=O)Cc3s2)c(F)c1
Show InChI InChI=1S/C17H16FN3O4S/c18-11-5-10(16(19)20)1-2-12(11)25-17(24)13-6-9-3-4-21(8-15(22)23)7-14(9)26-13/h1-2,5-6H,3-4,7-8H2,(H3,19,20)(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.560n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234258
PNG
(US9346821, B-36)
Show SMILES CC(C)C[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C25H31FN4O7S/c1-13(2)10-18(23(33)29-17(24(34)35)6-9-21(31)32)30(3)12-15-5-8-20(38-15)25(36)37-19-7-4-14(22(27)28)11-16(19)26/h4-5,7-8,11,13,17-18H,6,9-10,12H2,1-3H3,(H3,27,28)(H,29,33)(H,31,32)(H,34,35)/t17-,18+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.610n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234261
PNG
(US9346821, B-42)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(Cn3cccc3C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C18H14FN3O4S/c19-12-8-10(16(20)21)3-5-14(12)26-18(25)15-6-4-11(27-15)9-22-7-1-2-13(22)17(23)24/h1-8H,9H2,(H3,20,21)(H,23,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.610n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234263
PNG
(US9346821, B-45)
Show SMILES NC(=N)c1ccc(OC(=O)c2cc3CCN(CC(=O)N(CC=C)[C@@H](CCC(O)=O)C(O)=O)Cc3s2)c(F)c1
Show InChI InChI=1S/C25H27FN4O7S/c1-2-8-30(17(24(34)35)4-6-22(32)33)21(31)13-29-9-7-14-11-19(38-20(14)12-29)25(36)37-18-5-3-15(23(27)28)10-16(18)26/h2-3,5,10-11,17H,1,4,6-9,12-13H2,(H3,27,28)(H,32,33)(H,34,35)/t17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.620n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234244
PNG
(US9346821, B-11)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N(CC=C)CC(O)=O)s2)c(F)c1
Show InChI InChI=1S/C23H25FN4O5S/c1-2-9-28(13-20(29)30)22(31)17-4-3-10-27(17)12-15-6-8-19(34-15)23(32)33-18-7-5-14(21(25)26)11-16(18)24/h2,5-8,11,17H,1,3-4,9-10,12-13H2,(H3,25,26)(H,29,30)/t17-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.640n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234239
PNG
(US9346821, A-10)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)o2)cc1
Show InChI InChI=1S/C21H24N4O9S/c22-18(23)12-3-5-13(6-4-12)34-21(29)17-8-7-14(33-17)10-25-9-1-2-16(25)19(26)24-15(20(27)28)11-35(30,31)32/h3-8,15-16H,1-2,9-11H2,(H3,22,23)(H,24,26)(H,27,28)(H,30,31,32)/t15-,16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.650n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234238
PNG
(US9346821, A-6)
Show SMILES NC(=N)c1ccc2cc(OC(=O)c3ccc(CN4CCC[C@@H]4C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)o3)ccc2c1
Show InChI InChI=1S/C25H26N4O9S/c26-22(27)16-4-3-15-11-17(6-5-14(15)10-16)38-25(33)21-8-7-18(37-21)12-29-9-1-2-20(29)23(30)28-19(24(31)32)13-39(34,35)36/h3-8,10-11,19-20H,1-2,9,12-13H2,(H3,26,27)(H,28,30)(H,31,32)(H,34,35,36)/t19-,20+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.670n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234254
PNG
(US9346821, B-27)
Show SMILES CC(C)[C@@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C23H27FN4O7S/c1-11(2)19(21(31)27-15(22(32)33)9-18(29)30)28(3)10-13-5-7-17(36-13)23(34)35-16-6-4-12(20(25)26)8-14(16)24/h4-8,11,15,19H,9-10H2,1-3H3,(H3,25,26)(H,27,31)(H,29,30)(H,32,33)/t15-,19+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.680n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234265
PNG
(US9346821, B-47)
Show SMILES CC(C)N(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C21H23FN4O7S/c1-10(2)26(21(32)25-14(19(29)30)8-17(27)28)9-12-4-6-16(34-12)20(31)33-15-5-3-11(18(23)24)7-13(15)22/h3-7,10,14H,8-9H2,1-2H3,(H3,23,24)(H,25,32)(H,27,28)(H,29,30)/t14-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.690n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234248
PNG
(US9346821, B-15)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C22H23FN4O7S/c23-13-8-11(19(24)25)3-5-16(13)34-22(33)17-6-4-12(35-17)10-27-7-1-2-15(27)20(30)26-14(21(31)32)9-18(28)29/h3-6,8,14-15H,1-2,7,9-10H2,(H3,24,25)(H,26,30)(H,28,29)(H,31,32)/t14-,15-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.690n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234262
PNG
(US9346821, B-43)
Show SMILES NC(=N)c1ccc(OC(=O)c2cc3CCN(CC(O)=O)Cc3s2)c(F)c1
Show InChI InChI=1S/C17H16FN3O4S/c18-11-5-10(16(19)20)1-2-12(11)25-17(24)13-6-9-3-4-21(8-15(22)23)7-14(9)26-13/h1-2,5-6H,3-4,7-8H2,(H3,19,20)(H,22,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.690n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234256
PNG
(US9346821, B-32)
Show SMILES CC(C)C[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C25H31FN4O7S/c1-13(2)10-18(23(33)29-17(24(34)35)6-9-21(31)32)30(3)12-15-5-8-20(38-15)25(36)37-19-7-4-14(22(27)28)11-16(19)26/h4-5,7-8,11,13,17-18H,6,9-10,12H2,1-3H3,(H3,27,28)(H,29,33)(H,31,32)(H,34,35)/t17-,18-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.700n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234255
PNG
(US9346821, B-29)
Show SMILES CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C28H29FN4O7S/c1-33(15-18-8-11-23(41-18)28(39)40-22-10-7-17(25(30)31)14-19(22)29)21(13-16-5-3-2-4-6-16)26(36)32-20(27(37)38)9-12-24(34)35/h2-8,10-11,14,20-21H,9,12-13,15H2,1H3,(H3,30,31)(H,32,36)(H,34,35)(H,37,38)/t20-,21-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.700n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234263
PNG
(US9346821, B-45)
Show SMILES NC(=N)c1ccc(OC(=O)c2cc3CCN(CC(=O)N(CC=C)[C@@H](CCC(O)=O)C(O)=O)Cc3s2)c(F)c1
Show InChI InChI=1S/C25H27FN4O7S/c1-2-8-30(17(24(34)35)4-6-22(32)33)21(31)13-29-9-7-14-11-19(38-20(14)12-29)25(36)37-18-5-3-15(23(27)28)10-16(18)26/h2-3,5,10-11,17H,1,4,6-9,12-13H2,(H3,27,28)(H,32,33)(H,34,35)/t17-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.710n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234252
PNG
(US9346821, B-23)
Show SMILES CC(C)[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C23H27FN4O7S/c1-11(2)19(21(31)27-15(22(32)33)9-18(29)30)28(3)10-13-5-7-17(36-13)23(34)35-16-6-4-12(20(25)26)8-14(16)24/h4-8,11,15,19H,9-10H2,1-3H3,(H3,25,26)(H,27,31)(H,29,30)(H,32,33)/t15-,19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.75n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234267
PNG
(US9346821, B-56)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CC=C)CC(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C24H25FN4O8S/c1-2-9-29(12-19(30)28-16(23(34)35)11-21(32)33)20(31)8-5-14-4-7-18(38-14)24(36)37-17-6-3-13(22(26)27)10-15(17)25/h2-4,6-7,10,16H,1,5,8-9,11-12H2,(H3,26,27)(H,28,30)(H,32,33)(H,34,35)/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.770n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234244
PNG
(US9346821, B-11)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N(CC=C)CC(O)=O)s2)c(F)c1
Show InChI InChI=1S/C23H25FN4O5S/c1-2-9-28(13-20(29)30)22(31)17-4-3-10-27(17)12-15-6-8-19(34-15)23(32)33-18-7-5-14(21(25)26)11-16(18)24/h2,5-8,11,17H,1,3-4,9-10,12-13H2,(H3,25,26)(H,29,30)/t17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.780n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234254
PNG
(US9346821, B-27)
Show SMILES CC(C)[C@@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C23H27FN4O7S/c1-11(2)19(21(31)27-15(22(32)33)9-18(29)30)28(3)10-13-5-7-17(36-13)23(34)35-16-6-4-12(20(25)26)8-14(16)24/h4-8,11,15,19H,9-10H2,1-3H3,(H3,25,26)(H,27,31)(H,29,30)(H,32,33)/t15-,19+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.780n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234257
PNG
(US9346821, B-35)
Show SMILES CC(C)C[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C24H29FN4O7S/c1-12(2)8-17(22(32)28-16(23(33)34)10-20(30)31)29(3)11-14-5-7-19(37-14)24(35)36-18-6-4-13(21(26)27)9-15(18)25/h4-7,9,12,16-17H,8,10-11H2,1-3H3,(H3,26,27)(H,28,32)(H,30,31)(H,33,34)/t16-,17-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.810n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234261
PNG
(US9346821, B-42)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(Cn3cccc3C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C18H14FN3O4S/c19-12-8-10(16(20)21)3-5-14(12)26-18(25)15-6-4-11(27-15)9-22-7-1-2-13(22)17(23)24/h1-8H,9H2,(H3,20,21)(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.820n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234237
PNG
(US9346821, A-5)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)o2)cc1
Show InChI InChI=1S/C21H24N4O9S/c22-18(23)12-3-5-13(6-4-12)34-21(29)17-8-7-14(33-17)10-25-9-1-2-16(25)19(26)24-15(20(27)28)11-35(30,31)32/h3-8,15-16H,1-2,9-11H2,(H3,22,23)(H,24,26)(H,27,28)(H,30,31,32)/t15-,16+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.820n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234242
PNG
(US9346821, A-21)
Show SMILES CC(C)N(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C21H24N4O8/c1-11(2)25(21(31)24-15(19(28)29)9-17(26)27)10-14-7-8-16(32-14)20(30)33-13-5-3-12(4-6-13)18(22)23/h3-8,11,15H,9-10H2,1-2H3,(H3,22,23)(H,24,31)(H,26,27)(H,28,29)/t15-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.840n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234264
PNG
(US9346821, B-46)
Show SMILES CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C19H19FN4O7S/c1-24(19(30)23-12(17(27)28)7-15(25)26)8-10-3-5-14(32-10)18(29)31-13-4-2-9(16(21)22)6-11(13)20/h2-6,12H,7-8H2,1H3,(H3,21,22)(H,23,30)(H,25,26)(H,27,28)/t12-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.870n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234258
PNG
(US9346821, B-36)
Show SMILES CC(C)C[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C25H31FN4O7S/c1-13(2)10-18(23(33)29-17(24(34)35)6-9-21(31)32)30(3)12-15-5-8-20(38-15)25(36)37-19-7-4-14(22(27)28)11-16(19)26/h4-5,7-8,11,13,17-18H,6,9-10,12H2,1-3H3,(H3,27,28)(H,29,33)(H,31,32)(H,34,35)/t17-,18+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.890n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234256
PNG
(US9346821, B-32)
Show SMILES CC(C)C[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C25H31FN4O7S/c1-13(2)10-18(23(33)29-17(24(34)35)6-9-21(31)32)30(3)12-15-5-8-20(38-15)25(36)37-19-7-4-14(22(27)28)11-16(19)26/h4-5,7-8,11,13,17-18H,6,9-10,12H2,1-3H3,(H3,27,28)(H,29,33)(H,31,32)(H,34,35)/t17-,18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.900n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234249
PNG
(US9346821, B-18)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCCC[C@H]3C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C23H25FN4O7S/c24-14-9-12(20(25)26)4-6-17(14)35-23(34)18-7-5-13(36-18)11-28-8-2-1-3-16(28)21(31)27-15(22(32)33)10-19(29)30/h4-7,9,15-16H,1-3,8,10-11H2,(H3,25,26)(H,27,31)(H,29,30)(H,32,33)/t15-,16-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.920n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234241
PNG
(US9346821, A-20)
Show SMILES CN(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C19H20N4O8/c1-23(19(29)22-13(17(26)27)8-15(24)25)9-12-6-7-14(30-12)18(28)31-11-4-2-10(3-5-11)16(20)21/h2-7,13H,8-9H2,1H3,(H3,20,21)(H,22,29)(H,24,25)(H,26,27)/t13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.940n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234245
PNG
(US9346821, B-12)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)s2)cc1
Show InChI InChI=1S/C21H24N4O8S2/c22-18(23)12-3-5-13(6-4-12)33-21(29)17-8-7-14(34-17)10-25-9-1-2-16(25)19(26)24-15(20(27)28)11-35(30,31)32/h3-8,15-16H,1-2,9-11H2,(H3,22,23)(H,24,26)(H,27,28)(H,30,31,32)/t15-,16+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.950n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234239
PNG
(US9346821, A-10)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)o2)cc1
Show InChI InChI=1S/C21H24N4O9S/c22-18(23)12-3-5-13(6-4-12)34-21(29)17-8-7-14(33-17)10-25-9-1-2-16(25)19(26)24-15(20(27)28)11-35(30,31)32/h3-8,15-16H,1-2,9-11H2,(H3,22,23)(H,24,26)(H,27,28)(H,30,31,32)/t15-,16-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.970n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234260
PNG
(US9346821, B-41)
Show SMILES CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C1(CCCC1)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C24H27FN4O7S/c1-29(24(8-2-3-9-24)23(35)28-16(21(32)33)11-19(30)31)12-14-5-7-18(37-14)22(34)36-17-6-4-13(20(26)27)10-15(17)25/h4-7,10,16H,2-3,8-9,11-12H2,1H3,(H3,26,27)(H,28,35)(H,30,31)(H,32,33)/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.970n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234268
PNG
(US9346821, B-59)
Show SMILES CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)[C@H](Cc1ccccc1)C(=O)N[C@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C27H27FN4O7S/c1-32(20(11-15-5-3-2-4-6-15)25(35)31-19(26(36)37)13-23(33)34)14-17-8-10-22(40-17)27(38)39-21-9-7-16(24(29)30)12-18(21)28/h2-10,12,19-20H,11,13-14H2,1H3,(H3,29,30)(H,31,35)(H,33,34)(H,36,37)/t19-,20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.980n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234253
PNG
(US9346821, B-26)
Show SMILES CC(C)[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C24H29FN4O7S/c1-12(2)20(22(32)28-16(23(33)34)6-9-19(30)31)29(3)11-14-5-8-18(37-14)24(35)36-17-7-4-13(21(26)27)10-15(17)25/h4-5,7-8,10,12,16,20H,6,9,11H2,1-3H3,(H3,26,27)(H,28,32)(H,30,31)(H,33,34)/t16-,20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234251
PNG
(US9346821, B-21)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CSC[C@H]3C(=O)N(CC=C)CC(O)=O)s2)c(F)c1
Show InChI InChI=1S/C22H23FN4O5S2/c1-2-7-26(10-19(28)29)21(30)16-11-33-12-27(16)9-14-4-6-18(34-14)22(31)32-17-5-3-13(20(24)25)8-15(17)23/h2-6,8,16H,1,7,9-12H2,(H3,24,25)(H,28,29)/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234245
PNG
(US9346821, B-12)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)s2)cc1
Show InChI InChI=1S/C21H24N4O8S2/c22-18(23)12-3-5-13(6-4-12)33-21(29)17-8-7-14(34-17)10-25-9-1-2-16(25)19(26)24-15(20(27)28)11-35(30,31)32/h3-8,15-16H,1-2,9-11H2,(H3,22,23)(H,24,26)(H,27,28)(H,30,31,32)/t15-,16+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.14n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM234259
PNG
(US9346821, B-37)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CNC3(CC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C21H21FN4O7S/c22-12-7-10(17(23)24)1-3-14(12)33-19(31)15-4-2-11(34-15)9-25-21(5-6-21)20(32)26-13(18(29)30)8-16(27)28/h1-4,7,13,25H,5-6,8-9H2,(H3,23,24)(H,26,32)(H,27,28)(H,29,30)/t13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.27n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234260
PNG
(US9346821, B-41)
Show SMILES CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C1(CCCC1)C(=O)N[C@@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C24H27FN4O7S/c1-29(24(8-2-3-9-24)23(35)28-16(21(32)33)11-19(30)31)12-14-5-7-18(37-14)22(34)36-17-6-4-13(20(26)27)10-15(17)25/h4-7,10,16H,2-3,8-9,11-12H2,1H3,(H3,26,27)(H,28,35)(H,30,31)(H,32,33)/t16-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.56n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234259
PNG
(US9346821, B-37)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CNC3(CC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1
Show InChI InChI=1S/C21H21FN4O7S/c22-12-7-10(17(23)24)1-3-14(12)33-19(31)15-4-2-11(34-15)9-25-21(5-6-21)20(32)26-13(18(29)30)8-16(27)28/h1-4,7,13,25H,5-6,8-9H2,(H3,23,24)(H,26,32)(H,27,28)(H,29,30)/t13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.57n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (human))
BDBM234268
PNG
(US9346821, B-59)
Show SMILES CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)[C@H](Cc1ccccc1)C(=O)N[C@H](CC(O)=O)C(O)=O
Show InChI InChI=1S/C27H27FN4O7S/c1-32(20(11-15-5-3-2-4-6-15)25(35)31-19(26(36)37)13-23(33)34)14-17-8-10-22(40-17)27(38)39-21-9-7-16(24(29)30)12-18(21)28/h2-10,12,19-20H,11,13-14H2,1H3,(H3,29,30)(H,31,35)(H,33,34)(H,36,37)/t19-,20-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3.31n/an/an/an/an/an/an/an/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%