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Patent code US9353067

Compile Data Set for Download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D4 receptor


(Homo sapiens (Human))
BDBM232947
PNG
(US9353067, R-55)
Show SMILES Oc1cccc(c1)N1CCN(Cc2nc3ccccc3c(=O)[nH]2)CC1
Show InChI InChI=1S/C19H20N4O2/c24-15-5-3-4-14(12-15)23-10-8-22(9-11-23)13-18-20-17-7-2-1-6-16(17)19(25)21-18/h1-7,12,24H,8-11,13H2,(H,20,21,25)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 500n/an/an/an/an/an/a



ATIR Holding S.A.

US Patent


Assay Description
Determination of binding to D4.4 receptor was performed using [3H]-YM-09151-2 (70-87 Ci/mmol, 0.3 nM), as a radioligand, in the presence of various c...


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D4 receptor


(Homo sapiens (Human))
BDBM232949
PNG
(US9353067, L-238)
Show SMILES Oc1ccccc1N1CCN(Cc2nc3ccccc3c(=O)[nH]2)CC1
Show InChI InChI=1S/C19H20N4O2/c24-17-8-4-3-7-16(17)23-11-9-22(10-12-23)13-18-20-15-6-2-1-5-14(15)19(25)21-18/h1-8,24H,9-13H2,(H,20,21,25)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/an/an/a



ATIR Holding S.A.

US Patent


Assay Description
Determination of binding to D4.4 receptor was performed using [3H]-YM-09151-2 (70-87 Ci/mmol, 0.3 nM), as a radioligand, in the presence of various c...


Citation and Details
More data for this
Ligand-Target Pair
Dopamine D4 receptor


(Homo sapiens (Human))
BDBM232948
PNG
(US9353067, L-221)
Show SMILES Oc1ccc(cc1)N1CCN(Cc2nc3ccccc3c(=O)[nH]2)CC1
Show InChI InChI=1S/C19H20N4O2/c24-15-7-5-14(6-8-15)23-11-9-22(10-12-23)13-18-20-17-4-2-1-3-16(17)19(25)21-18/h1-8,24H,9-13H2,(H,20,21,25)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.00E+4n/an/an/an/an/an/a



ATIR Holding S.A.

US Patent


Assay Description
Determination of binding to D4.4 receptor was performed using [3H]-YM-09151-2 (70-87 Ci/mmol, 0.3 nM), as a radioligand, in the presence of various c...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%