Compile Data Set for Download or QSAR
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Found 24 Enz. Inhib. hit(s) with all data for entry = 8121
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234208(US9359293, TM)
Affinity DataIC50:  50nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50:  120nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50:  310nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234206(US9359293, TB)
Affinity DataIC50:  2.40E+3nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234206(US9359293, TB)
Affinity DataIC50:  3.00E+3nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234205(US9359293, TA)
Affinity DataIC50:  3.00E+4nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234205(US9359293, TA)
Affinity DataIC50:  1.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50:  1.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234206(US9359293, TB)
Affinity DataIC50:  1.13E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234208(US9359293, TM)
Affinity DataIC50:  1.24E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234208(US9359293, TM)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234208(US9359293, TM)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234208(US9359293, TM)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234208(US9359293, TM)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234206(US9359293, TB)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234206(US9359293, TB)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234205(US9359293, TA)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234205(US9359293, TA)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234205(US9359293, TA)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234205(US9359293, TA)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234206(US9359293, TB)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent