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Found 35 Enz. Inhib. hit(s) with all data for entry = 8207
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236623(US9388136, Table 1, Compound 15:tert-butyl N-(2- {...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236631(US9388136, Table 1, Compound 23:Cyclopentyl N- (2-...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236630(US9388136, Table 1, Compound 22:tert-butyl (2S)- [...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236629(US9388136, Table 1, Compound 21:Cyclopentyl (2S)- ...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236625(US9388136, Table 1, Compound 17:cyclopentyl N-(2- ...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236628(US9388136, Table 1, Compound 20:Cyclopentyl N- (2-...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236615(US9388136, Table 1, Compound 1:tert-Butyl N-(2-{4-...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236632(US9388136, Table 1, Compound 24:tert-butyl N-(2- {...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236619(US9388136, Table 1, Compound 11:Cyclopentyl (2S)-4...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236620(US9388136, Table 1, Compound 12:Cyclopentyl N-(5-{...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236618(US9388136, Table 1, Compound 5:tert-Butyl N-(5- {4...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236624(US9388136, Table 1, Compound 16:tert-butyl N-(2- {...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236619(US9388136, Table 1, Compound 11:Cyclopentyl (2S)-4...)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236628(US9388136, Table 1, Compound 20:Cyclopentyl N- (2-...)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236615(US9388136, Table 1, Compound 1:tert-Butyl N-(2-{4-...)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236626(US9388136, Table 1, Compound 18:Cyclopentyl N- [2-...)
Affinity DataIC50:  22nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236621(US9388136, Table 1, Compound 13:Ethyl N-(3- {4-[6-...)
Affinity DataIC50:  28nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236630(US9388136, Table 1, Compound 22:tert-butyl (2S)- [...)
Affinity DataIC50:  44nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236633(US9388136, Table 1, Compound 25:Cyclopentyl (2R)- ...)
Affinity DataIC50:  47nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236627(US9388136, Table 1, Compound 19:Cyclopentyl N- [2-...)
Affinity DataIC50:  56nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236631(US9388136, Table 1, Compound 23:Cyclopentyl N- (2-...)
Affinity DataIC50:  57nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236622(US9388136, Table 1, Compound 14:tert-butyl N- [2-(...)
Affinity DataIC50:  58nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236617(US9388136, Table 1, Compound 3:tert-Butyl N-[2-(4-...)
Affinity DataIC50:  58nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236622(US9388136, Table 1, Compound 14:tert-butyl N- [2-(...)
Affinity DataIC50:  58nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236629(US9388136, Table 1, Compound 21:Cyclopentyl (2S)- ...)
Affinity DataIC50:  65nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236627(US9388136, Table 1, Compound 19:Cyclopentyl N- [2-...)
Affinity DataIC50:  68nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236632(US9388136, Table 1, Compound 24:tert-butyl N-(2- {...)
Affinity DataIC50:  72nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236618(US9388136, Table 1, Compound 5:tert-Butyl N-(5- {4...)
Affinity DataIC50:  73nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236620(US9388136, Table 1, Compound 12:Cyclopentyl N-(5-{...)
Affinity DataIC50:  81nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236616(US9388136, Table 1, Compound 2:tert-Butyl N-[2-(4-...)
Affinity DataIC50:  118nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236623(US9388136, Table 1, Compound 15:tert-butyl N-(2- {...)
Affinity DataIC50:  120nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236624(US9388136, Table 1, Compound 16:tert-butyl N-(2- {...)
Affinity DataIC50:  167nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236625(US9388136, Table 1, Compound 17:cyclopentyl N-(2- ...)
Affinity DataIC50:  231nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236617(US9388136, Table 1, Compound 3:tert-Butyl N-[2-(4-...)
Affinity DataIC50:  330nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236616(US9388136, Table 1, Compound 2:tert-Butyl N-[2-(4-...)
Affinity DataIC50:  724nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent