Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 8222
TargetCytochrome P450 3A4(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM237157(US9394307, 4-chloro-N-(5-methyl-2-{1H-pyrazolo[3,4...)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:The test compounds were incubated with pooled human liver microsomes at 37° C. in the presence of NADPH and appropriate concentrations of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM237158(US9394307, 4-chloro-N-(2-{5-methoxy-1H,3aH,7aH-pyr...)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:The test compounds were incubated with pooled human liver microsomes at 37° C. in the presence of NADPH and appropriate concentrations of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM237159(US9394307, N-(2-{1H,3aH,7aH-pyrrolo[2,3-b]pyridine...)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:The test compounds were incubated with pooled human liver microsomes at 37° C. in the presence of NADPH and appropriate concentrations of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM237160(US9394307, 4-chloro-N-(5-chloro-2-{7H-pyrrolo[2,3-...)
Affinity DataIC50:  1.50E+4nMT: 2°CAssay Description:The test compounds were incubated with pooled human liver microsomes at 37° C. in the presence of NADPH and appropriate concentrations of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM50398343(CHEMBL2178573 | US9394307, 4-chloro-N-(5-methyl-2-...)
Affinity DataIC50:  2.00E+4nMT: 2°CAssay Description:The test compounds were incubated with pooled human liver microsomes at 37° C. in the presence of NADPH and appropriate concentrations of substra...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM50398343(CHEMBL2178573 | US9394307, 4-chloro-N-(5-methyl-2-...)
Affinity DataIC50:  2.00E+4nMT: 2°CAssay Description:The test compounds were incubated with pooled human liver microsomes at 37° C. in the presence of NADPH and appropriate concentrations of substra...More data for this Ligand-Target Pair
In DepthDetails US Patent