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Patent code US9409931

Compile Data Set for Download or QSAR
Found 8 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C delta type


(Homo sapiens (human))
BDBM239072
PNG
(US9409931, 5)
Show SMILES C[C@@H]1C[C@@H]2[C@H]([C@@H]3C=C(CO)C[C@@H]4[C@@H](OC(=O)C5(C)CCCCC5)C(C)=C[C@@]14C3=O)C2(C)C
Show InChI InChI=1S/C28H40O4/c1-16-14-28-17(2)11-20-22(26(20,3)4)19(24(28)30)12-18(15-29)13-21(28)23(16)32-25(31)27(5)9-7-6-8-10-27/h12,14,17,19-23,29H,6-11,13,15H2,1-5H3/t17-,19+,20-,21-,22?,23+,28-/m1/s1
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.11E+3n/an/an/an/a



LEO LABORATORIES LIMITED

US Patent


Assay Description
On the day at experiment Human Protein Kinase C delta (PKCδ, Millipore cat#14-504) was diluted in 20 mM HEPES, 0.03% Triton X-100. Amount of enz...


Citation and Details
More data for this
Ligand-Target Pair
Protein kinase C beta II type


(Homo sapiens (Human))
BDBM239070
PNG
(US9409931, 6)
Show SMILES C[C@@H]1C[C@@H]2[C@H]([C@@H]3C=C(CO)C[C@]4(O)[C@@H](OC(=O)C5(C)CCCCC5)C(C)=C[C@@]14C3=O)C2(C)C
Show InChI InChI=1S/C28H40O5/c1-16-13-27-17(2)11-20-21(25(20,3)4)19(22(27)30)12-18(15-29)14-28(27,32)23(16)33-24(31)26(5)9-7-6-8-10-26/h12-13,17,19-21,23,29,32H,6-11,14-15H2,1-5H3/t17-,19+,20-,21?,23+,27+,28+/m1/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.800n/an/an/an/a



LEO LABORATORIES LIMITED

US Patent


Assay Description
On the day at experiment Human Protein Kinase C betaII (PKCbII, Millipore cat#14-496) was incubated with 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 ...


Citation and Details
More data for this
Ligand-Target Pair
Protein kinase C beta II type


(Homo sapiens (Human))
BDBM239069
PNG
(US9409931, 8)
Show SMILES CC1=C[C@@]23CC[C@@H]4[C@H]([C@H](C=C(CO)[C@@H](O)[C@]2(O)[C@H]1OC(=O)C1(C)CCCCC1)C3=O)C4(C)C
Show InChI InChI=1S/C27H38O6/c1-15-13-26-11-8-18-19(24(18,2)3)17(21(26)30)12-16(14-28)20(29)27(26,32)22(15)33-23(31)25(4)9-6-5-7-10-25/h12-13,17-20,22,28-29,32H,5-11,14H2,1-4H3/t17-,18+,19?,20+,22-,26+,27-/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.100n/an/an/an/a



LEO LABORATORIES LIMITED

US Patent


Assay Description
On the day at experiment Human Protein Kinase C betaII (PKCbII, Millipore cat#14-496) was incubated with 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 ...


Citation and Details
More data for this
Ligand-Target Pair
Protein kinase C beta II type


(Homo sapiens (Human))
BDBM239072
PNG
(US9409931, 5)
Show SMILES C[C@@H]1C[C@@H]2[C@H]([C@@H]3C=C(CO)C[C@@H]4[C@@H](OC(=O)C5(C)CCCCC5)C(C)=C[C@@]14C3=O)C2(C)C
Show InChI InChI=1S/C28H40O4/c1-16-14-28-17(2)11-20-22(26(20,3)4)19(24(28)30)12-18(15-29)13-21(28)23(16)32-25(31)27(5)9-7-6-8-10-27/h12,14,17,19-23,29H,6-11,13,15H2,1-5H3/t17-,19+,20-,21-,22?,23+,28-/m1/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 6n/an/an/an/a



LEO LABORATORIES LIMITED

US Patent


Assay Description
On the day at experiment Human Protein Kinase C betaII (PKCbII, Millipore cat#14-496) was incubated with 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 ...


Citation and Details
More data for this
Ligand-Target Pair
Protein kinase C beta II type


(Homo sapiens (Human))
BDBM239071
PNG
(US9409931, 7)
Show SMILES C[C@@H]1C[C@@H]2[C@H]([C@@H]3C=C(CO)[C@@H](O)[C@@H]4[C@@H](OC(=O)C5(C)CCCCC5)C(C)=CC14C3=O)C2(C)C
Show InChI InChI=1S/C28H40O5/c1-15-13-28-16(2)11-19-20(26(19,3)4)18(24(28)31)12-17(14-29)22(30)21(28)23(15)33-25(32)27(5)9-7-6-8-10-27/h12-13,16,18-23,29-30H,6-11,14H2,1-5H3/t16-,18+,19-,20?,21-,22-,23+,28?/m1/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.200n/an/an/an/a



LEO LABORATORIES LIMITED

US Patent


Assay Description
On the day at experiment Human Protein Kinase C betaII (PKCbII, Millipore cat#14-496) was incubated with 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 ...


Citation and Details
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (human))
BDBM239071
PNG
(US9409931, 7)
Show SMILES C[C@@H]1C[C@@H]2[C@H]([C@@H]3C=C(CO)[C@@H](O)[C@@H]4[C@@H](OC(=O)C5(C)CCCCC5)C(C)=CC14C3=O)C2(C)C
Show InChI InChI=1S/C28H40O5/c1-15-13-28-16(2)11-19-20(26(19,3)4)18(24(28)31)12-17(14-29)22(30)21(28)23(15)33-25(32)27(5)9-7-6-8-10-27/h12-13,16,18-23,29-30H,6-11,14H2,1-5H3/t16-,18+,19-,20?,21-,22-,23+,28?/m1/s1
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 154n/an/an/an/a



LEO LABORATORIES LIMITED

US Patent


Assay Description
On the day at experiment Human Protein Kinase C delta (PKCδ, Millipore cat#14-504) was diluted in 20 mM HEPES, 0.03% Triton X-100. Amount of enz...


Citation and Details
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (human))
BDBM239070
PNG
(US9409931, 6)
Show SMILES C[C@@H]1C[C@@H]2[C@H]([C@@H]3C=C(CO)C[C@]4(O)[C@@H](OC(=O)C5(C)CCCCC5)C(C)=C[C@@]14C3=O)C2(C)C
Show InChI InChI=1S/C28H40O5/c1-16-13-27-17(2)11-20-21(25(20,3)4)19(22(27)30)12-18(15-29)14-28(27,32)23(16)33-24(31)26(5)9-7-6-8-10-26/h12-13,17,19-21,23,29,32H,6-11,14-15H2,1-5H3/t17-,19+,20-,21?,23+,27+,28+/m1/s1
PDB
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 80n/an/an/an/a



LEO LABORATORIES LIMITED

US Patent


Assay Description
On the day at experiment Human Protein Kinase C delta (PKCδ, Millipore cat#14-504) was diluted in 20 mM HEPES, 0.03% Triton X-100. Amount of enz...


Citation and Details
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (human))
BDBM239069
PNG
(US9409931, 8)
Show SMILES CC1=C[C@@]23CC[C@@H]4[C@H]([C@H](C=C(CO)[C@@H](O)[C@]2(O)[C@H]1OC(=O)C1(C)CCCCC1)C3=O)C4(C)C
Show InChI InChI=1S/C27H38O6/c1-15-13-26-11-8-18-19(24(18,2)3)17(21(26)30)12-16(14-28)20(29)27(26,32)22(15)33-23(31)25(4)9-6-5-7-10-25/h12-13,17-20,22,28-29,32H,5-11,14H2,1-4H3/t17-,18+,19?,20+,22-,26+,27-/m0/s1
PDB
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 7n/an/an/an/a



LEO LABORATORIES LIMITED

US Patent


Assay Description
On the day at experiment Human Protein Kinase C delta (PKCδ, Millipore cat#14-504) was diluted in 20 mM HEPES, 0.03% Triton X-100. Amount of enz...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%