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Patent code US9422261

Compile Data Set for Download or QSAR
Found 11 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM240726
PNG
(US9422261, Compound 4)
Show SMILES CC(c1ccsc1)c1ccc(O)cc1O
Show InChI InChI=1S/C12H12O2S/c1-8(9-4-5-15-7-9)11-3-2-10(13)6-12(11)14/h2-8,13-14H,1H3
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UniChem
US Patent
n/an/a 80n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM240723
PNG
(US9422261, Compound 1)
Show SMILES CC(c1cccs1)c1ccc(O)cc1O
Show InChI InChI=1S/C12H12O2S/c1-8(12-3-2-6-15-12)10-5-4-9(13)7-11(10)14/h2-8,13-14H,1H3
UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 90n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM240731
PNG
(US9422261, 4-(1- phenylethyl) benzene-1,3- diol)
Show SMILES CC(c1ccccc1)c1ccc(O)cc1O
Show InChI InChI=1S/C14H14O2/c1-10(11-5-3-2-4-6-11)13-8-7-12(15)9-14(13)16/h2-10,15-16H,1H3
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UniChem
US Patent
n/an/a 100n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM240725
PNG
(US9422261, Compound 3)
Show SMILES CC(c1cccnc1)c1ccc(O)cc1O
Show InChI InChI=1S/C13H13NO2/c1-9(10-3-2-6-14-8-10)12-5-4-11(15)7-13(12)16/h2-9,15-16H,1H3
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UniChem
US Patent
n/an/a 200n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM240724
PNG
(US9422261, Compound 2)
Show SMILES CC(c1ccccn1)c1ccc(O)cc1O
Show InChI InChI=1S/C13H13NO2/c1-9(12-4-2-3-7-14-12)11-6-5-10(15)8-13(11)16/h2-9,15-16H,1H3
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UniChem
US Patent
n/an/a 400n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM50248158
PNG
(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Show SMILES CCCCc1ccc(O)cc1O
Show InChI InChI=1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3
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US Patent
n/an/a 1.00E+3n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM240727
PNG
(US9422261, Compound 5)
Show SMILES CC(c1nccs1)c1ccc(O)cc1O
Show InChI InChI=1S/C11H11NO2S/c1-7(11-12-4-5-15-11)9-3-2-8(13)6-10(9)14/h2-7,13-14H,1H3
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UniChem
US Patent
n/an/a 1.50E+3n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM240729
PNG
(US9422261, Unigen resorcinol derivative | US968291...)
Show SMILES Oc1ccc(Cc2cccnc2)c(O)c1
Show InChI InChI=1S/C12H11NO2/c14-11-4-3-10(12(15)7-11)6-9-2-1-5-13-8-9/h1-5,7-8,14-15H,6H2
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UniChem
US Patent
n/an/a 2.00E+3n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM240730
PNG
(US9422261, Unigen resorcinol derivative | US968291...)
Show SMILES OC(c1cccnc1)c1ccc(O)cc1O
Show InChI InChI=1S/C12H11NO3/c14-9-3-4-10(11(15)6-9)12(16)8-2-1-5-13-7-8/h1-7,12,14-16H
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US Patent
n/an/a 4.90E+3n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
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US Patent
n/an/a 1.50E+4n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (White button mushroom))
BDBM240728
PNG
(US9422261, Arbutin)
Show SMILES OCC1O[C@@H](Oc2ccc(O)cc2)C(O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8?,9-,10+,11?,12-/m1/s1
UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 9.00E+4n/an/an/an/an/an/a



PIERRE FABRE DERMO-COSMETIQUE

US Patent


Assay Description
Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%