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Found 11 Enz. Inhib. hit(s) with all data for entry = 8307
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM240726(US9422261, Compound 4)
Affinity DataIC50:  80nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM240723(US9422261, Compound 1)
Affinity DataIC50:  90nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM240731(US9422261, 4-(1- phenylethyl) benzene-1,3- diol)
Affinity DataIC50:  100nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM240725(US9422261, Compound 3)
Affinity DataIC50:  200nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM240724(US9422261, Compound 2)
Affinity DataIC50:  400nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM50248158(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Affinity DataIC50:  1.00E+3nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM240727(US9422261, Compound 5)
Affinity DataIC50:  1.50E+3nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM240729(US9422261, Unigen resorcinol derivative | US968291...)
Affinity DataIC50:  2.00E+3nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM240730(US9422261, Unigen resorcinol derivative | US968291...)
Affinity DataIC50:  4.90E+3nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.50E+4nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM240728(US9422261, Arbutin)
Affinity DataIC50:  9.00E+4nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
In DepthDetails US Patent