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Found 65 Enz. Inhib. hit(s) with all data for entry = 8354
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242739(US9422297, PDDF)
Affinity DataIC50:  60nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetThymidylate synthase(Escherichia coli)
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242739(US9422297, PDDF)
Affinity DataIC50:  60nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM4567(4-anilinoquinazoline deriv. 2 | BMC163482 Compound...)
Affinity DataIC50:  130nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  230nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50314077(5-(p-tolylthio)-9H-pyrimido[4,5-b]indole-2,4-diami...)
Affinity DataIC50:  390nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM4567(4-anilinoquinazoline deriv. 2 | BMC163482 Compound...)
Affinity DataIC50:  521nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50314076(5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamin...)
Affinity DataIC50:  540nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242726(US9422297, AAG145-136 )
Affinity DataIC50:  800nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThymidylate synthase(Escherichia coli)
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50027655(CHEBI:5847 | Raltitrexed | Tomudex | US9422297, Ra...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50314076(5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamin...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242725(US9422297, AAG145-135 )
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50111603(3-(4-(dimethylamino)benzylidene)indolin-2-one | 3-...)
Affinity DataIC50:  3.75E+3nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242736(US9422297, AAG145-344)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242731(US9422297, AAG145-164 )
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242730(US9422297, AAG145-161 )
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242723(US9422297, AAG145-126 )
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242723(US9422297, AAG145-126 )
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242725(US9422297, AAG145-135 )
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThymidylate synthase(Escherichia coli)
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50027656(CHEBI:63616 | LY-2315 | LY-231514 | PEMETREXED | U...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50314076(5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamin...)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242727(US9422297, AAG145-157 )
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242722(US9422297, AAG145-124 )
Affinity DataIC50:  2.17E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242738(US9422297, AAG145-347)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50314076(5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamin...)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242735(US9422297, AAG145-342)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242724(US9422297, AAG145-131 )
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242726(US9422297, AAG145-136 )
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThymidylate synthase(Escherichia coli)
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50314077(5-(p-tolylthio)-9H-pyrimido[4,5-b]indole-2,4-diami...)
Affinity DataIC50: >2.60E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThymidylate synthase(Escherichia coli)
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50314076(5-(phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamin...)
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50027655(CHEBI:5847 | Raltitrexed | Tomudex | US9422297, Ra...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM50027656(CHEBI:63616 | LY-2315 | LY-231514 | PEMETREXED | U...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242723(US9422297, AAG145-126 )
Affinity DataIC50:  4.26E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242729(US9422297, AAG145-159 )
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242728(US9422297, AAG145-158 )
Affinity DataIC50:  4.31E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242721(US9422297, AAG145-335)
Affinity DataIC50:  4.51E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242730(US9422297, AAG145-161 )
Affinity DataIC50:  5.57E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242731(US9422297, AAG145-164 )
Affinity DataIC50:  7.29E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242737(US9422297, AAG145-346)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242729(US9422297, AAG145-159 )
Affinity DataIC50:  7.55E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242732(US9422297, AAG155-336)
Affinity DataIC50:  9.88E+4nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242724(US9422297, AAG145-131 )
Affinity DataIC50:  1.26E+5nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242733(US9422297, AAG145-340)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242727(US9422297, AAG145-157 )
Affinity DataIC50:  1.34E+5nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242734(US9422297, AAG145-341)
Affinity DataIC50:  1.63E+5nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242732(US9422297, AAG155-336)
Affinity DataIC50:  1.68E+5nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242728(US9422297, AAG145-158 )
Affinity DataIC50:  1.71E+5nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University Of The Holy Ghost

US Patent
LigandPNGBDBM242725(US9422297, AAG145-135 )
Affinity DataIC50:  1.97E+5nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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