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Found 20 Enz. Inhib. hit(s) with all data for entry = 8418
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  1.27nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  3.08nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  5.27nMAssay Description:Inhibition of VEGF-stimulated VEGFR-2 autophosphorylation in intact cells.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  8.5nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  8.79nMAssay Description:Inhibition of recombinant FGFR-2 tyrosine kinase using exogenous substrate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  10.1nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  10.6nMAssay Description:Inhibition of recombinant VEGFR-2 tyrosine kinase using exogenous substrate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  11.1nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  33.9nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  54.2nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  122nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  161nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  207nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  419nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  500nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  1.86E+3nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of recombinant PDGFR tyrosine kinase using exogenous substrate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  3.12E+3nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  5.85E+3nMAssay Description:Inhibition of recombinant EGFR tyrosine kinase using exogenous substrate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInsulin receptor(Homo sapiens (Human))
Panoptica

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of recombinant IR tyrosine kinase using exogenous substrate.More data for this Ligand-Target Pair
In DepthDetails US Patent