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Patent code US9447095

Compile Data Set for Download or QSAR
Found 30 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247389
PNG
(US9447095, 36)
Show SMILES Nc1nc(nc(NCc2cncs2)c1Br)-n1ncc2ccncc12
Show InChI InChI=1S/C14H11BrN8S/c15-11-12(16)21-14(22-13(11)19-5-9-4-18-7-24-9)23-10-6-17-2-1-8(10)3-20-23/h1-4,6-7H,5H2,(H3,16,19,21,22)
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n/an/a 0.0600n/an/an/an/an/an/a



PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247390
PNG
(US9447095, 39)
Show SMILES Cc1ncsc1CNc1nc(nc(N)c1Br)-n1ncc2cnccc12
Show InChI InChI=1S/C15H13BrN8S/c1-8-11(25-7-20-8)6-19-14-12(16)13(17)22-15(23-14)24-10-2-3-18-4-9(10)5-21-24/h2-5,7H,6H2,1H3,(H3,17,19,22,23)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247387
PNG
(US9447095, 34)
Show SMILES Cc1ncsc1CNc1nc(nc(N)c1Br)-n1ncc2ccncc12
Show InChI InChI=1S/C15H13BrN8S/c1-8-11(25-7-20-8)6-19-14-12(16)13(17)22-15(23-14)24-10-5-18-3-2-9(10)4-21-24/h2-5,7H,6H2,1H3,(H3,17,19,22,23)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247391
PNG
(US9447095, 41)
Show SMILES Cc1ncsc1CNc1nc(nc(N)c1Br)-n1ncc2ncccc12
Show InChI InChI=1S/C15H13BrN8S/c1-8-11(25-7-20-8)6-19-14-12(16)13(17)22-15(23-14)24-10-3-2-4-18-9(10)5-21-24/h2-5,7H,6H2,1H3,(H3,17,19,22,23)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247393
PNG
(US9447095, 45)
Show SMILES Nc1nc(nc(NCc2cncs2)c1Br)-n1cncn1
Show InChI InChI=1S/C10H9BrN8S/c11-7-8(12)17-10(19-4-14-3-16-19)18-9(7)15-2-6-1-13-5-20-6/h1,3-5H,2H2,(H3,12,15,17,18)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247378
PNG
(US9447095, 9)
Show SMILES Nc1nc(nc(NCc2cncs2)c1Br)-n1ncc2ccccc12
Show InChI InChI=1S/C15H12BrN7S/c16-12-13(17)21-15(22-14(12)19-7-10-6-18-8-24-10)23-11-4-2-1-3-9(11)5-20-23/h1-6,8H,7H2,(H3,17,19,21,22)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247388
PNG
(US9447095, 35)
Show SMILES Nc1nc(nc(NCC2CC2)c1Br)-n1ncc2ccncc12
Show InChI InChI=1S/C14H14BrN7/c15-11-12(16)20-14(21-13(11)18-5-8-1-2-8)22-10-7-17-4-3-9(10)6-19-22/h3-4,6-8H,1-2,5H2,(H3,16,18,20,21)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247379
PNG
(US9447095, 10)
Show SMILES Cc1ncsc1CNc1nc(nc(N)c1Br)-n1ncc2ccccc12
Show InChI InChI=1S/C16H14BrN7S/c1-9-12(25-8-20-9)7-19-15-13(17)14(18)22-16(23-15)24-11-5-3-2-4-10(11)6-21-24/h2-6,8H,7H2,1H3,(H3,18,19,22,23)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247386
PNG
(US9447095, 33)
Show SMILES Nc1nc(nc(NCC#C)c1Br)-n1ncc2ccncc12
Show InChI InChI=1S/C13H10BrN7/c1-2-4-17-12-10(14)11(15)19-13(20-12)21-9-7-16-5-3-8(9)6-18-21/h1,3,5-7H,4H2,(H3,15,17,19,20)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247394
PNG
(US9447095, 46)
Show SMILES Nc1nc(nc(NCC2CC2)c1Br)-n1cncn1
Show InChI InChI=1S/C10H12BrN7/c11-7-8(12)16-10(18-5-13-4-15-18)17-9(7)14-3-6-1-2-6/h4-6H,1-3H2,(H3,12,14,16,17)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247385
PNG
(US9447095, 30)
Show SMILES Nc1nc(nc(NCC#C)c1Br)-n1cc(cn1)-c1cnccn1
Show InChI InChI=1S/C14H11BrN8/c1-2-3-19-13-11(15)12(16)21-14(22-13)23-8-9(6-20-23)10-7-17-4-5-18-10/h1,4-8H,3H2,(H3,16,19,21,22)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247392
PNG
(US9447095, 42)
Show SMILES Nc1nc(nc(NCC#C)c1Br)-n1cncn1
Show InChI InChI=1S/C9H8BrN7/c1-2-3-13-8-6(10)7(11)15-9(16-8)17-5-12-4-14-17/h1,4-5H,3H2,(H3,11,13,15,16)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247382
PNG
(US9447095, 20)
Show SMILES Nc1nc(nc(NCc2cncs2)c1Br)-n1cc(cn1)-c1ccccn1
Show InChI InChI=1S/C16H13BrN8S/c17-13-14(18)23-16(24-15(13)21-7-11-6-19-9-26-11)25-8-10(5-22-25)12-3-1-2-4-20-12/h1-6,8-9H,7H2,(H3,18,21,23,24)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247396
PNG
(US9447095, 53)
Show SMILES CCNc1nc(nc(N)c1Br)-n1cc(cn1)C(=O)N1CCOCC1
Show InChI InChI=1S/C14H18BrN7O2/c1-2-17-12-10(15)11(16)19-14(20-12)22-8-9(7-18-22)13(23)21-3-5-24-6-4-21/h7-8H,2-6H2,1H3,(H3,16,17,19,20)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247383
PNG
(US9447095, 23)
Show SMILES Nc1nc(nc(NC2CCOCC2)c1Br)-n1cc(cn1)-c1ccc2ccccc2n1
Show InChI InChI=1S/C21H20BrN7O/c22-18-19(23)27-21(28-20(18)25-15-7-9-30-10-8-15)29-12-14(11-24-29)17-6-5-13-3-1-2-4-16(13)26-17/h1-6,11-12,15H,7-10H2,(H3,23,25,27,28)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247399
PNG
(US9447095, 64)
Show SMILES CCNc1nc(nc(N)c1Cl)-n1ncc2ccccc12
Show InChI InChI=1S/C13H13ClN6/c1-2-16-12-10(14)11(15)18-13(19-12)20-9-6-4-3-5-8(9)7-17-20/h3-7H,2H2,1H3,(H3,15,16,18,19)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247384
PNG
(US9447095, 29)
Show SMILES Cc1ncsc1CNc1nc(nc(N)c1Br)-n1cc(cn1)-c1cnccn1
Show InChI InChI=1S/C16H14BrN9S/c1-9-12(27-8-22-9)6-21-15-13(17)14(18)24-16(25-15)26-7-10(4-23-26)11-5-19-2-3-20-11/h2-5,7-8H,6H2,1H3,(H3,18,21,24,25)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247381
PNG
(US9447095, 17)
Show SMILES Nc1nc(nc(NCC#C)c1Br)-n1cc(cn1)-c1ccccn1
Show InChI InChI=1S/C15H12BrN7/c1-2-6-19-14-12(16)13(17)21-15(22-14)23-9-10(8-20-23)11-5-3-4-7-18-11/h1,3-5,7-9H,6H2,(H3,17,19,21,22)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247375
PNG
(US9447095, 6)
Show SMILES Cc1nc(CNc2nc(nc(N)c2Br)-n2ncc3ccccc23)cs1
Show InChI InChI=1S/C16H14BrN7S/c1-9-21-11(8-25-9)7-19-15-13(17)14(18)22-16(23-15)24-12-5-3-2-4-10(12)6-20-24/h2-6,8H,7H2,1H3,(H3,18,19,22,23)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247373
PNG
(US9447095, 2)
Show SMILES CCNc1nc(nc(N)c1Br)-n1ncc2ccccc12
Show InChI InChI=1S/C13H13BrN6/c1-2-16-12-10(14)11(15)18-13(19-12)20-9-6-4-3-5-8(9)7-17-20/h3-7H,2H2,1H3,(H3,15,16,18,19)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247376
PNG
(US9447095, 7)
Show SMILES Nc1nc(nc(NC2CCOCC2)c1Br)-n1ncc2ccccc12
Show InChI InChI=1S/C16H17BrN6O/c17-13-14(18)21-16(22-15(13)20-11-5-7-24-8-6-11)23-12-4-2-1-3-10(12)9-19-23/h1-4,9,11H,5-8H2,(H3,18,20,21,22)
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PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247380
PNG
(US9447095, 11)
Show SMILES COCCNc1nc(nc(N)c1Br)-n1ncc2ccccc12
Show InChI InChI=1S/C14H15BrN6O/c1-22-7-6-17-13-11(15)12(16)19-14(20-13)21-10-5-3-2-4-9(10)8-18-21/h2-5,8H,6-7H2,1H3,(H3,16,17,19,20)
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n/an/a 25.9n/an/an/an/an/an/a



PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247401
PNG
(US9447095, 77)
Show SMILES CCNc1nc(nc(NCc2nc3ccccc3[nH]2)c1Br)-n1cc(cn1)-c1ccncn1
Show InChI InChI=1S/C21H19BrN10/c1-2-24-19-18(22)20(25-10-17-28-15-5-3-4-6-16(15)29-17)31-21(30-19)32-11-13(9-27-32)14-7-8-23-12-26-14/h3-9,11-12H,2,10H2,1H3,(H,28,29)(H2,24,25,30,31)
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US Patent
n/an/a 29.3n/an/an/an/an/an/a



PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247395
PNG
(US9447095, 51)
Show SMILES Nc1nc(nc(NCC2CC2)c1Br)-n1cc(cn1)C(O)=O
Show InChI InChI=1S/C12H13BrN6O2/c13-8-9(14)17-12(18-10(8)15-3-6-1-2-6)19-5-7(4-16-19)11(20)21/h4-6H,1-3H2,(H,20,21)(H3,14,15,17,18)
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US Patent
n/an/a 29.9n/an/an/an/an/an/a



PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247398
PNG
(US9447095, 61)
Show SMILES CCNc1nc(nc(N)c1Br)-n1cc(cn1)-c1ccncn1
Show InChI InChI=1S/C13H13BrN8/c1-2-17-12-10(14)11(15)20-13(21-12)22-6-8(5-19-22)9-3-4-16-7-18-9/h3-7H,2H2,1H3,(H3,15,17,20,21)
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US Patent
n/an/a 37n/an/an/an/an/an/a



PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247374
PNG
(US9447095, 3)
Show SMILES Nc1nc(nc(NCC#C)c1Br)-n1ncc2ccccc12
Show InChI InChI=1S/C14H11BrN6/c1-2-7-17-13-11(15)12(16)19-14(20-13)21-10-6-4-3-5-9(10)8-18-21/h1,3-6,8H,7H2,(H3,16,17,19,20)
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US Patent
n/an/a 40.9n/an/an/an/an/an/a



PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247372
PNG
(US9447095, 1)
Show SMILES Nc1nc(nc(NCC2CC2)c1Br)-n1ncc2ccccc12
Show InChI InChI=1S/C15H15BrN6/c16-12-13(17)20-15(21-14(12)18-7-9-5-6-9)22-11-4-2-1-3-10(11)8-19-22/h1-4,8-9H,5-7H2,(H3,17,18,20,21)
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US Patent
n/an/a 52.5n/an/an/an/an/an/a



PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247377
PNG
(US9447095, 8)
Show SMILES Cn1cc(CNc2nc(nc(N)c2Br)-n2ncc3ccccc23)cn1
Show InChI InChI=1S/C16H15BrN8/c1-24-9-10(7-20-24)6-19-15-13(17)14(18)22-16(23-15)25-12-5-3-2-4-11(12)8-21-25/h2-5,7-9H,6H2,1H3,(H3,18,19,22,23)
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US Patent
n/an/a 74.1n/an/an/an/an/an/a



PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247397
PNG
(US9447095, 55)
Show SMILES Nc1nc(nc(c1Br)-n1cccn1)-n1cc(cn1)-c1ccccn1
Show InChI InChI=1S/C15H11BrN8/c16-12-13(17)21-15(22-14(12)23-7-3-6-19-23)24-9-10(8-20-24)11-4-1-2-5-18-11/h1-9H,(H2,17,21,22)
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US Patent
n/an/a 90.7n/an/an/an/an/an/a



PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM247400
PNG
(US9447095, 66)
Show SMILES CCNc1nc(nc(NCC#C)c1Br)-n1ncc2ccccc12
Show InChI InChI=1S/C16H15BrN6/c1-3-9-19-15-13(17)14(18-4-2)21-16(22-15)23-12-8-6-5-7-11(12)10-20-23/h1,5-8,10H,4,9H2,2H3,(H2,18,19,21,22)
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US Patent
n/an/a 120n/an/an/an/an/an/a



PALOBIOFARMA S.L.

US Patent


Assay Description
The analysis of the activity of the enzyme Phosphodiesterase [3H] cAMP SPA (Perkin Elmer #7090 TRKQ) kit was used for the study of Phosphodiesterase ...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%