Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 8425
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247405(US9452985, THK-5125)
Affinity DataKi:  9.20nM ΔG°:  -45.9kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247403(US9452985, THK-5117)
Affinity DataKi:  10.5nM ΔG°:  -45.5kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247407(US9452985, THK-5129)
Affinity DataKi:  21.4nM ΔG°:  -43.8kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247404(US9452985, THK-5122)
Affinity DataKi:  34.9nM ΔG°:  -42.6kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247402(US9452985, THK-5116)
Affinity DataKi:  36nM ΔG°:  -42.5kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247406(US9452985, THK-5151)
Affinity DataKi:  40.1nM ΔG°:  -42.2kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247408(US9452985, THK-523 (reference for comparison))
Affinity DataKi:  59.3nM ΔG°:  -41.2kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM50185987(2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...)
Affinity DataKi:  256nM ΔG°:  -37.6kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
In DepthDetails US Patent