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Found 2 Enz. Inhib. hit(s) with all data for entry = 8514
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Tianjin Institute Of Pharmaceutical Research

US Patent
LigandPNGBDBM254941(US10294259, Compound Table 3.2 | US9505734, I-D1-6)
Affinity DataIC50:  0.690nMAssay Description:The IC50 value of the inhibition of the cocrystal of I-D1-6 and L-proline prepared in Example 138 on SGLT2 and SGLT1 is measured according to the met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Tianjin Institute Of Pharmaceutical Research

US Patent
LigandPNGBDBM254941(US10294259, Compound Table 3.2 | US9505734, I-D1-6)
Affinity DataIC50:  259nMAssay Description:The IC50 value of the inhibition of the cocrystal of I-D1-6 and L-proline prepared in Example 138 on SGLT2 and SGLT1 is measured according to the met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent