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Patent code US9518060

Compile Data Set for Download or QSAR
Found 98 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286349
PNG
(US9518060, Example K7)
Show SMILES C[C@@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
0.165n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286350
PNG
(US9518060, Example K8)
Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
0.181n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286348
PNG
(US9518060, Example K6)
Show SMILES COCCCN1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
0.376n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286347
PNG
(US9518060, Example K5)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCCOC)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
0.683n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286345
PNG
(US9518060, Example K3)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
0.912n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286246
PNG
(5-{[(8S)-6,8-dimethyl-6,9-diazaspiro[4.5]dec-9-yl]...)
Show SMILES C[C@H]1CN(C)C2(CCCC2)CN1C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
1.01n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286343
PNG
(N-(2-ethoxy-5-fluoropyrimidin-4-yl)-6,6-dimethyl-5...)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C)CC2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
1.12n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286320
PNG
(US9518060, Example J6)
Show SMILES C[C@H]1CC(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
1.17n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286270
PNG
(US9518060, Example E2)
Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCCOC)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
1.64n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286377
PNG
(US9518060, Example L4)
Show SMILES CN1CCC(F)(CC1)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
1.71n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286310
PNG
(N-(5-fluoro-2-propylpyrimidin-4-yl)-6,6-dimethyl-5...)
Show SMILES C.CCCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)NC[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
1.73n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286260
PNG
(US9518060, Example B3)
Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
2.03n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286327
PNG
(N-[5-fluoro-2-(methoxymethyl)pyrimidin-4-yl]-6,6-d...)
Show SMILES COCc1ncc(F)c(Nc2c[nH]c3c2CN(C(=O)C2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
2.10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286344
PNG
(US9518060, Example K2)
Show SMILES CCOc1ccc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CC)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
2.11n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286264
PNG
(US9518060, Example B6)
Show SMILES C[C@@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3ccnc(n3)C#N)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
2.43n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286316
PNG
(US9518060, Example J3)
Show SMILES CC1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
2.63n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286227
PNG
(N4-(6,6-dimethyl-5-{[(2S)-2,4,5,5-tetramethylpiper...)
Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
2.69n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286346
PNG
(US9518060, Example K4)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCOC)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
3.33n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286244
PNG
(US9518060, Example A8)
Show SMILES CCNc1nccc(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
3.39n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286311
PNG
(US9518060, Example I2)
Show SMILES CC(C)c1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
3.67n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286242
PNG
(US9518060, Example A7)
Show SMILES CC(C)Nc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
3.81n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286239
PNG
(US9518060, Example A5)
Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(NC4CC4)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
3.95n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286380
PNG
(N-(4-ethoxypyrimidin-2-yl)-6,6-dimethyl-5-{[(2S,5R...)
Show SMILES CCOc1ccnc(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
4.24n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286257
PNG
(N2-ethyl-5-fluoro-N4-(5-{[(2S,5R)-4-(3-methoxyprop...)
Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCCOC)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
5.09n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286267
PNG
(N-(2-ethyl-5-fluoropyrimidin-4-yl)-6,6-dimethyl-5-...)
Show SMILES CCc1ccc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
5.43n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286318
PNG
(US9518060, Example J5)
Show SMILES C[C@H]1CN2CCC[C@H]2CN1C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
6.43n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286279
PNG
(US9518060, Example H3)
Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
7.21n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286317
PNG
(US9518060, Example J4)
Show SMILES C[C@H]1CN2CCC[C@@]2(C)CN1C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
8.64n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286231
PNG
(US9518060, Example A2)
Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(ncc3F)N(C)C)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
8.75n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286245
PNG
(US9518060, Example A9)
Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3ccnc(n3)N(C)C)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
9.73n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286273
PNG
(2-((5S)-4-{[3-[(2-ethyl-5-fluoropyrimidin-4-yl)ami...)
Show SMILES C.CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)NC[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286335
PNG
(US9518060, Example J13)
Show SMILES C[C@@H]1CN([C@@H](C)CN1C1CCOCC1)C(=O)N1Cc2c(Nc3nccc(n3)C(F)(F)F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286362
PNG
(US9518060, Example K19)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CC4CCOCC4)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286368
PNG
(US9518060, Example K23 | US9518060, Example K24)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286365
PNG
(5-{[(2S,5R)-2,5-dimethyl-4-(tetrahydro-2H-pyran-4-...)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C[C@@H]2C)C2CCOCC2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286332
PNG
(US9518060, Example J12)
Show SMILES C[C@@H]1CN([C@@H](C)CN1C1CCOCC1)C(=O)N1Cc2c(Nc3nccc(C)n3)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286251
PNG
(US9518060, Example A12)
Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C[C@@H]2C)C2CCOCC2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286248
PNG
(N4-(5-{[(2S,5R)-2,5-dimethyl-4-(tetrahydro-2H-pyra...)
Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CC4CCOCC4)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286368
PNG
(US9518060, Example K23 | US9518060, Example K24)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286384
PNG
(5-{[(2S,5R)-2,5-dimethyl-4-(tetrahydro-2H-pyran-4-...)
Show SMILES COCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)C2C[C@@H](C)N(CC4CCOCC4)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286340
PNG
(US9518060, Example J15)
Show SMILES C[C@@H]1CN([C@@H](C)CN1CC1CCOCC1)C(=O)N1Cc2c(Nc3nccc(C)n3)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286330
PNG
(US9518060, Example J10)
Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CC4CCOCC4)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286385
PNG
(US9518060, Example N2 | US9518060, Example N3)
Show SMILES COCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286331
PNG
(US9518060, Example J11)
Show SMILES COc1ccnc(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C[C@@H]2C)C2CCOCC2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
<10n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286269
PNG
(N-(2-ethyl-5-fluoropyrimidin-4-yl)-6,6-dimethyl-5-...)
Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
10.5n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286241
PNG
(US9518060, Example A6)
Show SMILES CNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
10.8n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286342
PNG
(US9518060, Example J16)
Show SMILES C[C@@H]1CN([C@@H](C)CN1CC1CCOCC1)C(=O)N1Cc2c(Nc3nc(C)cc(C)n3)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
11.1n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286357
PNG
(US9518060, Example K15)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@]4(C)CCCN4C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
11.2n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286351
PNG
(US9518060, Example K9)
Show SMILES C.C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(OCCCO)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
12.8n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286271
PNG
(US9518060, Example E3)
Show SMILES CCOc1nccc(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)C(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
13.1n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286261
PNG
(US9518060, Example B4)
Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCOC)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
13.5n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286254
PNG
(US9518060, Example AA3)
Show SMILES CCN1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(C)nc(C)c3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
14.8n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286292
PNG
(US9518060, Example H6)
Show SMILES C[C@@H]1CN([C@@H](C)CN1CC1CCOCC1)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
14.9n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286354
PNG
(US9518060, Example K12)
Show SMILES COCCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
15.2n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286366
PNG
(US9518060, Example K22)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CCN(CC4(O)CCOCC4)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
15.3n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286385
PNG
(US9518060, Example N2 | US9518060, Example N3)
Show SMILES COCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
15.6n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286382
PNG
(US9518060, Example M2)
Show SMILES CCOc1ccnc(Nc2n[nH]c3c2CN(C(=O)C2C[C@@H](C)N(CCCOC)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
16.1n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286372
PNG
(N-(2-ethoxy-5-fluoropyrimidin-4-yl)-5-[(4-fluoro-1...)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)C2(F)CCN(C)CC2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
16.8n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286232
PNG
(US9518060, Example A3)
Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(NCC4CC4)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
17.9n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286278
PNG
(US9518060, Example H2)
Show SMILES C.C[C@@H]1CN([C@@H](C)CN1)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
18.1n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286253
PNG
(US9518060, Example AA2)
Show SMILES CCN1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
18.9n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286337
PNG
(US9518060, Example J14)
Show SMILES COc1ccnc(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CC4CCOCC4)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
19.2n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286265
PNG
(US9518060, Example B7)
Show SMILES C[C@@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3nc(ncc3F)N3CCOCC3)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
20.1n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286312
PNG
(5-[(4-fluoro-1-methylpiperidin-4-yl)carbonyl]-N-(3...)
Show SMILES CN1CCC(F)(CC1)C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
21.2n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286299
PNG
(US9518060, Example H7)
Show SMILES C[C@@H]1CN([C@@H](C)CN1C1CCOCC1)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
22n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286252
PNG
(5-{[(2S,5R)-4-ethyl-2,5-dimethylpiperazin-1-yl]car...)
Show SMILES CCN1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(OC)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
22.9n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286258
PNG
(US9518060, Example B2)
Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC4CCCN4C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
24.5n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286361
PNG
(US9518060, Example K18)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCC(F)(F)F)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
25.3n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286275
PNG
(N-(2-ethyl-5-fluoropyrimidin-4-yl)-5-[(4-fluoro-1-...)
Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)C2(F)CCN(C)CC2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
25.4n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286363
PNG
(US9518060, Example K20)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H]4CCCN4C[C@@H]2C(C)C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
26n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286355
PNG
(US9518060, Example K13)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@H](C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
26.5n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286352
PNG
(US9518060, Example K10)
Show SMILES C.C[C@@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3nc(OCCCO)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
28.4n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286256
PNG
(US9518060, Example AA5)
Show SMILES C[C@@H]1CN([C@@H](C)CN1CCCO)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
29.1n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286263
PNG
(US9518060, Example B5)
Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCC(F)(F)F)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
29.8n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286272
PNG
(5-{[(2S,5R)-2,5-dimethyl-4-(3,3,3-trifluoropropyl)...)
Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCC(F)(F)F)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
31.5n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286324
PNG
(US9518060, Example J8)
Show SMILES C[C@@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3cccc(C)n3)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
32n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286266
PNG
(N2-ethyl-5-fluoro-N4-{5-[(4-fluoro-1-methylpiperid...)
Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)C2(F)CCN(C)CC2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
33.4n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286370
PNG
(US9518060, Example K25 | US9518060, Example K26)
Show SMILES COc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
36.5n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286234
PNG
(US9518060, Example A4)
Show SMILES CC(C)CNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
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UniChem
37.6n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286358
PNG
(US9518060, Example K16)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CCN(C)C(C)C2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
38.4n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286277
PNG
(N-(5-fluoro-2-methylpyrimidin-4-yl)-6,6-dimethyl-5...)
Show SMILES C[C@H]1CN2CCC[C@H]2CN1C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
39.8n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286274
PNG
(5-[(4-fluoro-1-methylpiperidin-4-yl)carbonyl]-N-(5...)
Show SMILES CN1CCC(F)(CC1)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
39.9n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286353
PNG
(US9518060, Example K11)
Show SMILES COCCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
42.7n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286360
PNG
(US9518060, Example K17)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CCN(C)[C@H](C)C2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
44.4n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286288
PNG
(US9518060, Example H5)
Show SMILES CC[C@@H]1CN(CCN1C)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
50.8n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286370
PNG
(US9518060, Example K25 | US9518060, Example K26)
Show SMILES COc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
54.7n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286303
PNG
(US9518060, Example H10 | US9518060, Example H9)
Show SMILES C.C[C@H]1CNC(CCO)CN1C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
58.2n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286375
PNG
(US9518060, Example L3)
Show SMILES COCCCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)C2(F)CCN(C)CC2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
58.6n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286313
PNG
(US9518060, Example J2)
Show SMILES CN1CCC(F)(CC1)C(=O)N1Cc2c(Nc3cccc(C)n3)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
59.9n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286356
PNG
(US9518060, Example K14)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CCN4CCC[C@@H]4C2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
71.7n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286280
PNG
(US9518060, Example H4)
Show SMILES CC[C@H]1CN(CCN1C)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
86n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286323
PNG
(US9518060, Example J7)
Show SMILES C[C@H]1CN2CCC[C@@]2(C)CN1C(=O)N1Cc2c(Nc3cccc(C)n3)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
111n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286378
PNG
(N-(2-ethoxy-5-fluoropyrimidin-4-yl)-6,6-dimethyl-5...)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)C2CCN(CCC(F)(F)F)CC2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
129n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286255
PNG
(US9518060, Example AA4)
Show SMILES C[C@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
147n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286301
PNG
(4-[((2R,5S)-4-{[3-[(5-fluoro-2-methylpyrimidin-4-y...)
Show SMILES C[C@@H]1CN([C@@H](C)CN1CC1(O)CCOCC1)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
157n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286374
PNG
(US9518060, Example L2)
Show SMILES COCCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)C2(F)CCN(C)CC2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
168n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286303
PNG
(US9518060, Example H10 | US9518060, Example H9)
Show SMILES C.C[C@H]1CNC(CCO)CN1C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
180n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM286379
PNG
(US9518060, Example L6)
Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)C2CCN(CC2)C2CCOCC2)C3(C)C)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
181n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...


US Patent US9518060 (2016)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%