Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 8582
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260151(US9522910, Table 1 Compound 1: 4-methyl-N-{4-[(4-m...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260157(US9522910, Table 1 Compound 8: 4-fluoro-N-{4-[(4-m...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260153(US9522910, Table 1 Compound 3: 3-{2-[2-methyl-5-({...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260154(US9522910, Table 1 Compound 4: 3-{2-[2-methyl-5-({...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260155(US9522910, Table 1 Compound 5: 4-methyl-N-{4-[(4-m...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260156(US9522910, Table 1 Compound 6: 3-{2-[2-methyl-5-({...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260158(US9522910, Table 1 Compound 7: 3-{2-[2-methyl-5-({...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260157(US9522910, Table 1 Compound 8: 4-fluoro-N-{4-[(4-m...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260151(US9522910, Table 1 Compound 1: 4-methyl-N-{4-[(4-m...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260152(US9522910, Table 1 Compound 2: 3-[2-(1H-1,3-benzod...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260153(US9522910, Table 1 Compound 3: 3-{2-[2-methyl-5-({...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260154(US9522910, Table 1 Compound 4: 3-{2-[2-methyl-5-({...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260155(US9522910, Table 1 Compound 5: 4-methyl-N-{4-[(4-m...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260156(US9522910, Table 1 Compound 6: 3-{2-[2-methyl-5-({...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260158(US9522910, Table 1 Compound 7: 3-{2-[2-methyl-5-({...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260152(US9522910, Table 1 Compound 2: 3-[2-(1H-1,3-benzod...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent