BindingDB logo
myBDB logout

Patent code US9556145

Compile Data Set for Download or QSAR
Found 22 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
hox2r flipr


(Homo sapiens (Human))
BDBM205090
PNG
(US9556145, example 10 | US9556145, example 11)
Show SMILES COC(=O)c1cc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)ncc1Br
Show InChI InChI=1S/C22H22BrN5O4/c1-14-7-8-15(32-20-11-17(22(30)31-2)18(23)12-24-20)13-27(14)21(29)16-5-3-4-6-19(16)28-25-9-10-26-28/h3-6,9-12,14-15H,7-8,13H2,1-2H3/t14-,15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox2r flipr


(Homo sapiens (Human))
BDBM205085
PNG
(US9556145, example 5 | methyl 3-chloro-2-(((3R,6R)...)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1Cl
Show InChI InChI=1S/C22H22ClN5O4/c1-14-7-8-15(32-20-19(23)17(9-10-24-20)22(30)31-2)13-27(14)21(29)16-5-3-4-6-18(16)28-25-11-12-26-28/h3-6,9-12,14-15H,7-8,13H2,1-2H3/t14-,15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox2r flipr


(Homo sapiens (Human))
BDBM205088
PNG
(US9556145, example 8 | methyl 3-fluoro-2-{[(3r,6r)...)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1F
Show InChI InChI=1S/C22H22FN5O4/c1-14-7-8-15(32-20-19(23)17(9-10-24-20)22(30)31-2)13-27(14)21(29)16-5-3-4-6-18(16)28-25-11-12-26-28/h3-6,9-12,14-15H,7-8,13H2,1-2H3/t14-,15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 24.9n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox2r flipr


(Homo sapiens (Human))
BDBM50084382
PNG
(CHEMBL3426138 | US9556145, example 1)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1
Show InChI InChI=1S/C22H23N5O4/c1-15-7-8-17(31-20-13-16(9-10-23-20)22(29)30-2)14-26(15)21(28)18-5-3-4-6-19(18)27-24-11-12-25-27/h3-6,9-13,15,17H,7-8,14H2,1-2H3/t15-,17-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 26n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM205083
PNG
(US9556145, example 3 | methyl 2-{[(3r,6r)-6- methy...)
Show SMILES COC(=O)c1cc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)ncc1C(F)(F)F
Show InChI InChI=1S/C23H22F3N5O4/c1-14-7-8-15(35-20-11-17(22(33)34-2)18(12-27-20)23(24,25)26)13-30(14)21(32)16-5-3-4-6-19(16)31-28-9-10-29-31/h3-6,9-12,14-15H,7-8,13H2,1-2H3/t14-,15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 28n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM205084
PNG
(US9556145, example 4 | methyl 5-bromo-2- {[(3r,6r)...)
Show SMILES COC(=O)c1cc(O[C@@H]2CC[C@@H](C)N(Cc3ccccc3-n3nccn3)C2)ncc1Br
Show InChI InChI=1S/C22H24BrN5O3/c1-15-7-8-17(31-21-11-18(22(29)30-2)19(23)12-24-21)14-27(15)13-16-5-3-4-6-20(16)28-25-9-10-26-28/h3-6,9-12,15,17H,7-8,13-14H2,1-2H3/t15-,17-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 28.9n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox2r flipr


(Homo sapiens (Human))
BDBM205086
PNG
(US9556145, example 6 | dimethyl 2-{[(3r,6r)-6-meth...)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1C(=O)OC
Show InChI InChI=1S/C24H25N5O6/c1-15-8-9-16(35-21-20(24(32)34-3)18(10-11-25-21)23(31)33-2)14-28(15)22(30)17-6-4-5-7-19(17)29-26-12-13-27-29/h4-7,10-13,15-16H,8-9,14H2,1-3H3/t15-,16-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 30.8n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM205090
PNG
(US9556145, example 10 | US9556145, example 11)
Show SMILES COC(=O)c1cc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)ncc1Br
Show InChI InChI=1S/C22H22BrN5O4/c1-14-7-8-15(32-20-11-17(22(30)31-2)18(23)12-24-20)13-27(14)21(29)16-5-3-4-6-19(16)28-25-9-10-26-28/h3-6,9-12,14-15H,7-8,13H2,1-2H3/t14-,15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 31n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox2r flipr


(Homo sapiens (Human))
BDBM205083
PNG
(US9556145, example 3 | methyl 2-{[(3r,6r)-6- methy...)
Show SMILES COC(=O)c1cc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)ncc1C(F)(F)F
Show InChI InChI=1S/C23H22F3N5O4/c1-14-7-8-15(35-20-11-17(22(33)34-2)18(12-27-20)23(24,25)26)13-30(14)21(32)16-5-3-4-6-19(16)31-28-9-10-29-31/h3-6,9-12,14-15H,7-8,13H2,1-2H3/t14-,15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 57n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox2r flipr


(Homo sapiens (Human))
BDBM205084
PNG
(US9556145, example 4 | methyl 5-bromo-2- {[(3r,6r)...)
Show SMILES COC(=O)c1cc(O[C@@H]2CC[C@@H](C)N(Cc3ccccc3-n3nccn3)C2)ncc1Br
Show InChI InChI=1S/C22H24BrN5O3/c1-15-7-8-17(31-21-11-18(22(29)30-2)19(23)12-24-21)14-27(15)13-16-5-3-4-6-20(16)28-25-9-10-26-28/h3-6,9-12,15,17H,7-8,13-14H2,1-2H3/t15-,17-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 60n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox2r flipr


(Homo sapiens (Human))
BDBM205087
PNG
(US9556145, example 7 | methyl 2-methyl-6-{[(3r,6r)...)
Show SMILES COC(=O)c1cc(C)nc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1
Show InChI InChI=1S/C23H25N5O4/c1-15-12-17(23(30)31-3)13-21(26-15)32-18-9-8-16(2)27(14-18)22(29)19-6-4-5-7-20(19)28-24-10-11-25-28/h4-7,10-13,16,18H,8-9,14H2,1-3H3/t16-,18-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 82.6n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox2r flipr


(Homo sapiens (Human))
BDBM205090
PNG
(US9556145, example 10 | US9556145, example 11)
Show SMILES COC(=O)c1cc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)ncc1Br
Show InChI InChI=1S/C22H22BrN5O4/c1-14-7-8-15(32-20-11-17(22(30)31-2)18(23)12-24-20)13-27(14)21(29)16-5-3-4-6-19(16)28-25-9-10-26-28/h3-6,9-12,14-15H,7-8,13H2,1-2H3/t14-,15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 96n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox2r flipr


(Homo sapiens (Human))
BDBM205089
PNG
(US9556145, example 9 | methyl 2-{[(3r,6r)-1-{[6- m...)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccc(OC)nc2-n2nccn2)c1
Show InChI InChI=1S/C22H24N6O5/c1-14-4-5-16(33-19-12-15(8-9-23-19)22(30)32-3)13-27(14)21(29)17-6-7-18(31-2)26-20(17)28-24-10-11-25-28/h6-12,14,16H,4-5,13H2,1-3H3/t14-,16-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 406n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM205086
PNG
(US9556145, example 6 | dimethyl 2-{[(3r,6r)-6-meth...)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1C(=O)OC
Show InChI InChI=1S/C24H25N5O6/c1-15-8-9-16(35-21-20(24(32)34-3)18(10-11-25-21)23(31)33-2)14-28(15)22(30)17-6-4-5-7-19(17)29-26-12-13-27-29/h4-7,10-13,15-16H,8-9,14H2,1-3H3/t15-,16-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 526n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM205090
PNG
(US9556145, example 10 | US9556145, example 11)
Show SMILES COC(=O)c1cc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)ncc1Br
Show InChI InChI=1S/C22H22BrN5O4/c1-14-7-8-15(32-20-11-17(22(30)31-2)18(23)12-24-20)13-27(14)21(29)16-5-3-4-6-19(16)28-25-9-10-26-28/h3-6,9-12,14-15H,7-8,13H2,1-2H3/t14-,15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 597n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM205085
PNG
(US9556145, example 5 | methyl 3-chloro-2-(((3R,6R)...)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1Cl
Show InChI InChI=1S/C22H22ClN5O4/c1-14-7-8-15(32-20-19(23)17(9-10-24-20)22(30)31-2)13-27(14)21(29)16-5-3-4-6-18(16)28-25-11-12-26-28/h3-6,9-12,14-15H,7-8,13H2,1-2H3/t14-,15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 953n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM50084382
PNG
(CHEMBL3426138 | US9556145, example 1)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1
Show InChI InChI=1S/C22H23N5O4/c1-15-7-8-17(31-20-13-16(9-10-23-20)22(29)30-2)14-26(15)21(28)18-5-3-4-6-19(18)27-24-11-12-25-27/h3-6,9-13,15,17H,7-8,14H2,1-2H3/t15-,17-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.40E+3n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM205087
PNG
(US9556145, example 7 | methyl 2-methyl-6-{[(3r,6r)...)
Show SMILES COC(=O)c1cc(C)nc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1
Show InChI InChI=1S/C23H25N5O4/c1-15-12-17(23(30)31-3)13-21(26-15)32-18-9-8-16(2)27(14-18)22(29)19-6-4-5-7-20(19)28-24-10-11-25-28/h4-7,10-13,16,18H,8-9,14H2,1-3H3/t16-,18-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.47E+3n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM205088
PNG
(US9556145, example 8 | methyl 3-fluoro-2-{[(3r,6r)...)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1F
Show InChI InChI=1S/C22H22FN5O4/c1-14-7-8-15(32-20-19(23)17(9-10-24-20)22(30)31-2)13-27(14)21(29)16-5-3-4-6-18(16)28-25-11-12-26-28/h3-6,9-12,14-15H,7-8,13H2,1-2H3/t14-,15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.69E+3n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox2r flipr


(Homo sapiens (Human))
BDBM205092
PNG
(US9556145, example 12)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccc(OC)nc2-c2ncccn2)c1
Show InChI InChI=1S/C24H25N5O5/c1-15-5-6-17(34-20-13-16(9-12-25-20)24(31)33-3)14-29(15)23(30)18-7-8-19(32-2)28-21(18)22-26-10-4-11-27-22/h4,7-13,15,17H,5-6,14H2,1-3H3/t15-,17-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.11E+3n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM205092
PNG
(US9556145, example 12)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccc(OC)nc2-c2ncccn2)c1
Show InChI InChI=1S/C24H25N5O5/c1-15-5-6-17(34-20-13-16(9-12-25-20)24(31)33-3)14-29(15)23(30)18-7-8-19(32-2)28-21(18)22-26-10-4-11-27-22/h4,7-13,15,17H,5-6,14H2,1-3H3/t15-,17-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
hox1r flipr


(Homo sapiens (Human))
BDBM205089
PNG
(US9556145, example 9 | methyl 2-{[(3r,6r)-1-{[6- m...)
Show SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccc(OC)nc2-n2nccn2)c1
Show InChI InChI=1S/C22H24N6O5/c1-14-4-5-16(33-19-12-15(8-9-23-19)22(30)32-3)13-27(14)21(29)17-6-7-18(31-2)26-20(17)28-24-10-11-25-28/h6-12,14,16H,4-5,13H2,1-3H3/t14-,16-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%