Compile Data Set for Download or QSAR
maximum 50k data
Found 86 Enz. Inhib. hit(s) with all data for entry = 225
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234970(US9556148, 41 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  0.600nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234972(US9556148, 43 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234969(US9556148, 40 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  1.30nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234967(4-(2-((4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)p...)
Affinity DataIC50:  1.5nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234970(US9556148, 41 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  2.5nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234971(4-(2-((4-(4-(1-oxa-8-azaspiro[4.5]decan-8-yl)piper...)
Affinity DataIC50:  2.5nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234972(US9556148, 43 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  2.60nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234969(US9556148, 40 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  2.80nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234943(US9556148, 2 | n-(cyanomethyl)-4-(2-((4-(4-(1,1-di...)
Affinity DataIC50:  4nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234971(4-(2-((4-(4-(1-oxa-8-azaspiro[4.5]decan-8-yl)piper...)
Affinity DataIC50:  4.30nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234967(4-(2-((4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)p...)
Affinity DataIC50:  4.30nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234973(US9556148, 44 | n-(cyanomethyl)-4-(5-fluoro-2-((4-...)
Affinity DataIC50:  4.90nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234959(US9556148, 27 | n-(cyanomethyl)-4-(2-((4-(4-(tetra...)
Affinity DataIC50:  5nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234968(4-(2-((4-(4-(6-acetyl-3,6-diazabicyclo[3.1.1]hepta...)
Affinity DataIC50:  5nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234957(4-(2-((4-(4-(1-oxa-8-azaspiro[4.5]decan-8-yl)piper...)
Affinity DataIC50:  5nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234957(4-(2-((4-(4-(1-oxa-8-azaspiro[4.5]decan-8-yl)piper...)
Affinity DataIC50:  5nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234943(US9556148, 2 | n-(cyanomethyl)-4-(2-((4-(4-(1,1-di...)
Affinity DataIC50:  5.10nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234942(US9556148, 1 | n-(cyanomethyl)-4-(2-((4-(4-(2-oxop...)
Affinity DataIC50:  5.60nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234960(US9556148, 28 | n-(cyanomethyl)-4-(2-((4-(4-(2-oxo...)
Affinity DataIC50:  6nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234946(US9556148, 3 | n-(cyanomethyl)-4-(2-((4-(4-morphol...)
Affinity DataIC50:  6.60nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234973(US9556148, 44 | n-(cyanomethyl)-4-(5-fluoro-2-((4-...)
Affinity DataIC50:  6.70nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234966(US9556148, 36 | n-(cyanomethyl)-4-(2-((4-(4-(5-met...)
Affinity DataIC50:  6.70nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234956(4-(2-((4-(4-(1,3,4-oxadiazol-2-yl)piperidin-1-yl)p...)
Affinity DataIC50:  7nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234951(US9556148, 9 | n-(cyanomethyl)-4-(2-((4-(4-(1,1-di...)
Affinity DataIC50:  8nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234954(4-(2-((4-(4-(6-oxa-3-azabicyclo[3.1.1]heptan-3-yl)...)
Affinity DataIC50:  8nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234958(US9556148, 25 | n-(cyanomethyl)-4-(2-((4-(4-(5-met...)
Affinity DataIC50:  8nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234968(4-(2-((4-(4-(6-acetyl-3,6-diazabicyclo[3.1.1]hepta...)
Affinity DataIC50:  8.80nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234955(US9556148, 18 | n-(cyanomethyl)-4-(2-((4-(4-(2-oxo...)
Affinity DataIC50:  9nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234966(US9556148, 36 | n-(cyanomethyl)-4-(2-((4-(4-(5-met...)
Affinity DataIC50:  9.20nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234959(US9556148, 27 | n-(cyanomethyl)-4-(2-((4-(4-(tetra...)
Affinity DataIC50:  10nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234956(4-(2-((4-(4-(1,3,4-oxadiazol-2-yl)piperidin-1-yl)p...)
Affinity DataIC50:  10nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234970(US9556148, 41 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  10.7nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234960(US9556148, 28 | n-(cyanomethyl)-4-(2-((4-(4-(2-oxo...)
Affinity DataIC50:  11nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234955(US9556148, 18 | n-(cyanomethyl)-4-(2-((4-(4-(2-oxo...)
Affinity DataIC50:  11nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234963(US9556148, 33 | n-(cyanomethyl)-4-(2-((4-(4-(4,5-d...)
Affinity DataIC50:  11nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234953(US9556148, 15 | n-(cyanomethyl)-4-(2-((4-(4-(tetra...)
Affinity DataIC50:  11nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234946(US9556148, 3 | n-(cyanomethyl)-4-(2-((4-(4-morphol...)
Affinity DataIC50:  11.7nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234950(US9556148, 7 | n-(cyanomethyl)-4-(2-((4-(4-(1,1-di...)
Affinity DataIC50:  12nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234958(US9556148, 25 | n-(cyanomethyl)-4-(2-((4-(4-(5-met...)
Affinity DataIC50:  12nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234942(US9556148, 1 | n-(cyanomethyl)-4-(2-((4-(4-(2-oxop...)
Affinity DataIC50:  12.1nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234954(4-(2-((4-(4-(6-oxa-3-azabicyclo[3.1.1]heptan-3-yl)...)
Affinity DataIC50:  13nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234964(US9556148, 34 | n-(cyanomethyl)-4-(2-((4-(4-(4,5-d...)
Affinity DataIC50:  13nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234951(US9556148, 9 | n-(cyanomethyl)-4-(2-((4-(4-(1,1-di...)
Affinity DataIC50:  14nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234950(US9556148, 7 | n-(cyanomethyl)-4-(2-((4-(4-(1,1-di...)
Affinity DataIC50:  14nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234961(US9556148, 29 | n-(cyanomethyl)-4-(2-((4-(4-(5-oxo...)
Affinity DataIC50:  15nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234965(US9556148, 35 | n-(cyanomethyl)-4-(2-((4-(3-(tetra...)
Affinity DataIC50:  15nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234953(US9556148, 15 | n-(cyanomethyl)-4-(2-((4-(4-(tetra...)
Affinity DataIC50:  16nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234949(4-(2-((4-([1,3'-bipyrrolidin]-1'-yl)phenyl)amino)p...)
Affinity DataIC50:  16nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234973(US9556148, 44 | n-(cyanomethyl)-4-(5-fluoro-2-((4-...)
Affinity DataIC50:  16.6nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234962(US9556148, 31 | n-(cyanomethyl)-4-(2-((4-(4-(5-met...)
Affinity DataIC50:  17nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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