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Patent code US9556170

Compile Data Set for Download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM227716
PNG
(US9556170, 3)
Show SMILES Oc1ccc(Cl)cc1Nc1nc2cc(ccc2[nH]1)S(=O)(=O)N1CCNCC1
Show InChI InChI=1S/C17H18ClN5O3S/c18-11-1-4-16(24)15(9-11)22-17-20-13-3-2-12(10-14(13)21-17)27(25,26)23-7-5-19-6-8-23/h1-4,9-10,19,24H,5-8H2,(H2,20,21,22)
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MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 81n/an/an/an/an/an/a



University of Utah Research Foundation

US Patent


Assay Description
Inhibition of LSD activity can be determined by a variety of both in vitro and in vivo methods known to one skilled in the art. For example, enzymati...


Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM50158877
PNG
(CHEMBL3786908 | US9556170, 1)
Show SMILES Oc1ccc(Cl)cc1Nc1nc2cc(ccc2[nH]1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C17H17ClN4O4S/c18-11-1-4-16(23)15(9-11)21-17-19-13-3-2-12(10-14(13)20-17)27(24,25)22-5-7-26-8-6-22/h1-4,9-10,23H,5-8H2,(H2,19,20,21)
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Patents


Similars

US Patent
n/an/a 90n/an/an/an/an/an/a



University of Utah Research Foundation

US Patent


Assay Description
Inhibition of LSD activity can be determined by a variety of both in vitro and in vivo methods known to one skilled in the art. For example, enzymati...


Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM227715
PNG
(US9556170, 2)
Show SMILES CN1CCN(CC1)S(=O)(=O)c1ccc2[nH]c(Nc3cc(Cl)ccc3O)nc2c1
Show InChI InChI=1S/C18H20ClN5O3S/c1-23-6-8-24(9-7-23)28(26,27)13-3-4-14-15(11-13)21-18(20-14)22-16-10-12(19)2-5-17(16)25/h2-5,10-11,25H,6-9H2,1H3,(H2,20,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 273n/an/an/an/an/an/a



University of Utah Research Foundation

US Patent


Assay Description
Inhibition of LSD activity can be determined by a variety of both in vitro and in vivo methods known to one skilled in the art. For example, enzymati...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%