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Found 4 Enz. Inhib. hit(s) with all data for entry = 791
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50003994(CHEMBL2180010 | US9579407, Example 00161)
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:Human PDE1A, 3A, 4D2, 5A1, 7B, 8A1, 9A2, and 11A4 enzymes were purchased from BPS Bioscience. Human PDE6AB enzyme was purchased from Scottish Biomedi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM290889(1-[2-fluoro-4- (tetrahydro-2H- pyran-4-yl)phenyl]-...)
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:Human PDE1A, 3A, 4D2, 5A1, 7B, 8A1, 9A2, and 11A4 enzymes were purchased from BPS Bioscience. Human PDE6AB enzyme was purchased from Scottish Biomedi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM290892(5-(fluoro-methyloxy- d2)-1-(2-fluoro-4- (tetrahydr...)
Affinity DataIC50: <10nMpH: 7.4 T: 2°CAssay Description:Human PDE1A, 3A, 4D2, 5A1, 7B, 8A1, 9A2, and 11A4 enzymes were purchased from BPS Bioscience. Human PDE6AB enzyme was purchased from Scottish Biomedi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM291105(5-(2-fluoro- ethyloxy-d4)-1-(2- fluoro-4- (tetrahy...)
Affinity DataIC50: <10nMpH: 7.4 T: 2°CAssay Description:Human PDE1A, 3A, 4D2, 5A1, 7B, 8A1, 9A2, and 11A4 enzymes were purchased from BPS Bioscience. Human PDE6AB enzyme was purchased from Scottish Biomedi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent