Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 793
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291171(US9580411, Example 86)
Affinity DataIC50:  9nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291170(2-[N-(Propan-2-yl)(4-fluorobenzene)sulfonamido]-N-...)
Affinity DataIC50:  13nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291169(1-(4-Fluoro-N-isopropylphenylsulfonamido)-N-((6-(6...)
Affinity DataIC50:  29nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291163(US9580411, Example 79-(R) | US9580411, Example 79-...)
Affinity DataIC50:  38nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291163(US9580411, Example 79-(R) | US9580411, Example 79-...)
Affinity DataIC50:  55nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291168(2,2-Dideuterio-2-(4-fluoro-N-isopropylphenylsulfon...)
Affinity DataIC50:  58nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291165(2-(4-Fluoro-N-isopropylphenylsulfonamido)-N-((6-(4...)
Affinity DataIC50:  251nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291161(2-(4-fluoro-N-isopropylphenylsulfonamido)-N-(3-(py...)
Affinity DataIC50:  883nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291162(N-(3-cyclopropylbenzyl)-2-(4-fluoro-N-isopropylphe...)
Affinity DataIC50:  1.00E+3nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291167(2-(N-Isopropyl-1-methyl-1H-pyrazole-3-sulfonamido)...)
Affinity DataIC50:  2.40E+3nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291166(N-((6-(4,4-Difluoropiperidin-1-yl)pyrimidin-4-yl)m...)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent