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Found 125 Enz. Inhib. hit(s) with all data for entry = 933
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50398017(CHEMBL2180411 | US9018217, 5,8-Dimethyl-2-[2-(1-me...)
Affinity DataIC50:  0.320nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM47287(US9018217, 5,7-Dimethyl-2-[2-(4-phenyl-1-propyl-1H...)
Affinity DataIC50:  0.690nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156359(US9018217, 8-Ethyl-5-methyl-2-[2-(1-methyl-4-pheny...)
Affinity DataIC50:  0.930nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM47296(US9018217, 8-Ethyl-5-methyl-2-(2-(1-methyl-4-pheny...)
Affinity DataIC50:  1.10nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM299447(US9592230, 5-Methyl-2-{2-[4-phenyl-1-(2-piperidin-...)
Affinity DataIC50:  1.30nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156347(US9018217, 2-[2-(1-Isobutyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50:  1.30nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156350(US9018217, 5,7-Dimethyl-2-{2-[1-(2-morpholin-4-yl-...)
Affinity DataIC50:  1.40nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156337(US9018217, 2-[2-(1-Isobutyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50:  1.60nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50398014(CHEMBL2180414 | US9018217, 5,8-Dimethyl-2-[2-(1-me...)
Affinity DataIC50:  1.80nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156352(US9018217, 8-methoxy-5-methyl-2-(2-(1-methyl-4-phe...)
Affinity DataIC50:  2.5nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156346(US9018217, 5,7-Dimethyl-2-{2-[4-phenyl-1-(2-piperi...)
Affinity DataIC50:  2.70nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156333(US9018217, 5-Methyl-2-[2-(4-phenyl-1H-imidazol-2-y...)
Affinity DataIC50:  2.80nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM47278(US9018217, 1-Methyl-3-(2-[2-[2-(5-methyl-[1,2,4]tr...)
Affinity DataIC50:  2.80nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156342(US9018217, 5-Methyl-2-[2-(1-methyl-4-phenyl-1H-imi...)
Affinity DataIC50:  2.80nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156348(US9018217, 2-[2-(1-Isopropyl-4-phenyl-1H-imidazol-...)
Affinity DataIC50:  3.40nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156354(US9018217, 5-Methyl-2-[2-(1-methyl-4-phenyl-1H-imi...)
Affinity DataIC50:  3.60nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156334(US9018217, 2-(1-Isobutyl-4-phenyl-1H-imidazol-2-yl...)
Affinity DataIC50:  4.20nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM47285(US9018217, 1-(2-[2-[2-(5,7-Dimethyl-[1,2,4]triazol...)
Affinity DataIC50:  4.40nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156356(US9018217, 7-Isopropyl-5-methyl-2-[2-(1-methyl-4-p...)
Affinity DataIC50:  4.80nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156335(US9018217, 5,7-Dimethyl-2-[1-(2-morpholin-4-yl-eth...)
Affinity DataIC50:  5nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156330(US9018217, 5,7-Dimethyl-2-[2-(4-phenyl-1H-imidazol...)
Affinity DataIC50:  5.30nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156255(US9018217, 5,7-Dimethyl-2-[1-(3-methyl-butyl)-4-ph...)
Affinity DataIC50:  5.40nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156351(US9018217, (S)-1-{2-[2-(5,7-Dimethyl-[1,2,4]triazo...)
Affinity DataIC50:  5.5nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156324(US9018217, 4-(2-(2-(2-(5,7-dimethyl-[1,2,4]triazol...)
Affinity DataIC50:  6nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156336(US9018217, 5-Methyl-2-[2-(1-methyl-4-phenyl-1H-imi...)
Affinity DataIC50:  6.90nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50398016(CHEMBL2180412 | US9018217, 5,8-Dimethyl-2-[2-(1-me...)
Affinity DataIC50:  7.20nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM47282(US9018217, Diisopropyl-(2-[2-[2-(5-methyl-[1,2,4]t...)
Affinity DataIC50:  7.30nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156344(US9018217, 5-Ethyl-2-(1-methyl-4-phenyl-1H-imidazo...)
Affinity DataIC50:  7.5nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156322(US9018217, 5-Methyl-2-{2-[1-(2-morpholin-4-yl-ethy...)
Affinity DataIC50:  8.10nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM47276(US9018217, 1-Methyl-3-(2-[2-[2-(5-methyl-[1,2,4]tr...)
Affinity DataIC50:  8.10nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156349(US9018217, (2-{2-[2-(5,7-Dimethyl-[1,2,4]triazolo[...)
Affinity DataIC50:  8.70nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156256(US9018217, 5,7-Dimethyl-2-(4-phenyl-1-propyl-1H-im...)
Affinity DataIC50:  9.10nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM47289(US9018217, (R)-1-[2-[2-(5,7-Dimethyl-[1,2,4]triazo...)
Affinity DataIC50:  11nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156257(US9018217, 2-(1-Cyclopropylmethyl-4-phenyl-1H-imid...)
Affinity DataIC50:  12nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156320(US9018217, 8-Methyl-2-[2-(1-methyl-4-phenyl-1H-Imi...)
Affinity DataIC50:  12nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156327(US9018217, 5,7-Dimethyl-2-[2-(1-methyl-4-phenyl-1H...)
Affinity DataIC50:  12nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM47288(US9018217, 1-[2-[2-(5,7-Dimethyl-[1,2,4]triazolo[1...)
Affinity DataIC50:  13nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156321(US9018217, 5-Methyl-2-[2-(1-methyl-4-phenyl-1H-imi...)
Affinity DataIC50:  14nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156358(US9018217, {5-Methyl-2-[2-(1-methyl-4-phenyl-1H-im...)
Affinity DataIC50:  15nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156341(US9018217, 5,6,7-Trimethyl-2-[2-(1-methyl-4-phenyl...)
Affinity DataIC50:  15nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156326(US9018217, 5,7-dimethyl-2-(2-(4-phenyl-1H-imidazol...)
Affinity DataIC50:  15nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50398015(CHEMBL2180413 | US9018217, 5,7-dimethyl-2-(2-(1-me...)
Affinity DataIC50:  17nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM47274(US9018217, 4-(2-(2-((8-chloro-[1,2,4]triazolo[1,5-...)
Affinity DataIC50:  17nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156325(US9018217, 6,8-dimethyl-2-(2-(1-methyl-4-phenyl-1H...)
Affinity DataIC50:  19nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156258(US9018217, 5,7-dimethyl-2((1-methyl-4-phenyl-1H-im...)
Affinity DataIC50:  20nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156259(US9018217, 5,7-Dimethyl-2-[1-(2-morpholin-4-yl-eth...)
Affinity DataIC50:  22nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156338(US9018217, 2-[2-(1-Isopropyl-4-phenyl-1H-imidazol-...)
Affinity DataIC50:  23nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156331(US9018217, 5,7-Dimethyl-2-(4-phenyl-1H-imidazol-2-...)
Affinity DataIC50:  24nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156332(US9018217, 5,7-Dimethyl-2-(1-methyl-4-phenyl-1H-im...)
Affinity DataIC50:  25nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM156340(US9018217, 1-{2-[2-(5,7-Dimethyl-[1,2,4]triazolo[1...)
Affinity DataIC50:  25nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
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