Compile Data Set for Download or QSAR
maximum 50k data
Found 194 Enz. Inhib. hit(s) with all data for entry = 944
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300129(3-[(2-Chlorophenyl)methyl]-5-cyclobutyl-7-(3,3-dif...)
Affinity DataEC50:  1nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300129(3-[(2-Chlorophenyl)methyl]-5-cyclobutyl-7-(3,3-dif...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300130(5-Cyclopropyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(...)
Affinity DataEC50:  6.40nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300130(5-Cyclopropyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300131(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50:  0.5nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300131(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50:  770nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300132(3-[(2-Chlorophenyl)methyl]-5-cyclopropyl-7-(3,3-di...)
Affinity DataEC50:  1nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300132(3-[(2-Chlorophenyl)methyl]-5-cyclopropyl-7-(3,3-di...)
Affinity DataEC50:  750nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300133(3-[[5-Cyclopropyl-7-(3,3-difluoropyrrolidin-1-yl)t...)
Affinity DataEC50:  1nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300133(3-[[5-Cyclopropyl-7-(3,3-difluoropyrrolidin-1-yl)t...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300134((3S)-1-[3-[(2-Chlorophenyl)methyl]-5-prop-1-en-2-y...)
Affinity DataEC50:  3.60nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300134((3S)-1-[3-[(2-Chlorophenyl)methyl]-5-prop-1-en-2-y...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300135(3-[(2-Chlorophenyl)methyl]-5,7-di(piperidin-1-yl)t...)
Affinity DataEC50:  9.20nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300135(3-[(2-Chlorophenyl)methyl]-5,7-di(piperidin-1-yl)t...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300136(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50:  4.5nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300136(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300137(5-(Azetidin-1-yl)-3-[(2-chlorophenyl)methyl]-7-(3,...)
Affinity DataEC50:  1.60nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300137(5-(Azetidin-1-yl)-3-[(2-chlorophenyl)methyl]-7-(3,...)
Affinity DataEC50:  363nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300138(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50:  2.90nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300138(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50:  217nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300139(3-[(2-Chlorophenyl)methyl]-N-cyclobutyl-7-(3,3-dif...)
Affinity DataEC50:  2.60nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300139(3-[(2-Chlorophenyl)methyl]-N-cyclobutyl-7-(3,3-dif...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300140(N-tert-Butyl-3-[(2-chlorophenyl)methyl]-7-(3,3-dif...)
Affinity DataEC50:  0.900nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300140(N-tert-Butyl-3-[(2-chlorophenyl)methyl]-7-(3,3-dif...)
Affinity DataEC50:  365nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300141(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50:  12.5nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300141(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300142(4-[3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrro...)
Affinity DataEC50:  3.5nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300142(4-[3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrro...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300144(N-tert-Butyl-3-[(2-chlorophenyl)methyl]-7-(3,3-dif...)
Affinity DataEC50:  2.20nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300144(N-tert-Butyl-3-[(2-chlorophenyl)methyl]-7-(3,3-dif...)
Affinity DataEC50:  336nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300145(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50:  3.10nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300145(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300146(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50:  26.6nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300146(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300147(3-[(2-Chlorophenyl)methyl]-N-cyclobutyl-7-(3,3-dif...)
Affinity DataEC50:  8.10nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300147(3-[(2-Chlorophenyl)methyl]-N-cyclobutyl-7-(3,3-dif...)
Affinity DataEC50:  967nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300148((3S)-1-[5-(tert-Butylamino)-3-[(4-methoxyphenyl)me...)
Affinity DataEC50:  27.4nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300148((3S)-1-[5-(tert-Butylamino)-3-[(4-methoxyphenyl)me...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300149(N-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(4...)
Affinity DataEC50:  20.3nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300149(N-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(4...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300150(N-[(3S)-1-[5-(tert-Butylamino)-3-[(4-methoxyphenyl...)
Affinity DataEC50:  141nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300150(N-[(3S)-1-[5-(tert-Butylamino)-3-[(4-methoxyphenyl...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300151(N-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[[2...)
Affinity DataEC50:  2.10nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300151(N-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[[2...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300152(N-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(2...)
Affinity DataEC50:  1.10nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300152(N-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(2...)
Affinity DataEC50:  487nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300153(N-tert-Butyl-3-[(3-chloropyridin-2-yl)methyl]-7-(3...)
Affinity DataEC50:  3.40nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300153(N-tert-Butyl-3-[(3-chloropyridin-2-yl)methyl]-7-(3...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300154(N-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(1...)
Affinity DataEC50:  7.5nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300154(N-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(1...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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