Compile Data Set for Download or QSAR
maximum 50k data
Found 260 Enz. Inhib. hit(s) with all data for entry = 989
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301790( N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)...)
Affinity DataKi:  0.390nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301861(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)-...)
Affinity DataKi:  1.90nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301779(4-Phenyl-N-(4-(4-phenylpiperazin-1-yl)butyl)pipera...)
Affinity DataKi:  2nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301854(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  2.30nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301856(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  2.30nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301845(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  2.60nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301814(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  2.70nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301793(N-(4-(4-(2-(tert-Butyl)-6-methylpyrimidin-4-yl)pip...)
Affinity DataKi:  2.70nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301869( N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimi...)
Affinity DataKi:  3nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301852(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  3.5nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301792(N-(4-(4-(3-Cyano-5-(trifluoromethyl)phenyl)piperaz...)
Affinity DataKi:  4.10nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057762(CHEMBL3323011 | US9598387, Compound 113 | US996974...)
Affinity DataKi:  4.20nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301844(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  5.90nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301866(N-(4-(4-(2-(tert-Butyl)-6-methylpyrimidin-4-yl)pip...)
Affinity DataKi:  7.30nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301843(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  8nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057763(CHEMBL3323016 | US9598387, Compound 115 | US996974...)
Affinity DataKi:  8nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057777(CHEMBL3323010 | US9598387, Compound 112 | US996974...)
Affinity DataKi:  8.40nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301847(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  8.60nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301879(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  8.60nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301840(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  8.70nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057779(CHEMBL3323008 | US9598387, Compound 111 | US996974...)
Affinity DataKi:  9.30nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301918(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  9.40nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301870(N-(4-(4-(2,6-Di-tert-butylpyrimidin-4-yl)piperazin...)
Affinity DataKi:  9.5nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301881(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  9.60nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301824(4-Phenyl-N-(4-(4-(quinolin-4-yl)piperazin-1-yl)but...)
Affinity DataKi:  9.80nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301878(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  9.80nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301890(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  9.90nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057767(CHEMBL3323017 | US9598387, Compound 116 | US996974...)
Affinity DataKi:  10.2nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301862(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  11nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301835(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  11.6nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057768(CHEMBL3323015 | US9598387, Compound 114 | US996974...)
Affinity DataKi:  11.8nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301853(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  12.2nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301848( N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimi...)
Affinity DataKi:  12.7nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301849(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  12.8nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301834(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  13nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301846(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  13.7nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301883(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  13.8nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301786(4-Phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  14.2nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301857( 4-([1,1′-Biphenyl]-2-yl)-N-(4-(4-(2-(tert-b...)
Affinity DataKi:  15nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301816( N-(4-(4-(2-(tert-Butyl)-6-cyclopropylpyrimidin-4-...)
Affinity DataKi:  15.1nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301821( N-(4-(4-(2,6-Di-tert-butylpyrimidin-4-yl)piperazi...)
Affinity DataKi:  15.1nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301831( N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimi...)
Affinity DataKi:  16nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301839( N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimi...)
Affinity DataKi:  16.6nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301850(4-Benzyl-N-(4-(4-(2-(tert-butyl)-6-(trifluoromethy...)
Affinity DataKi:  16.7nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301891(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  18nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301864( 4-Benzyl-N-(4-(4-(2-(tert-butyl)-6-(trifluorometh...)
Affinity DataKi:  18.4nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM50057778(CHEMBL3323009 | US9598387, Compound 122 | US996974...)
Affinity DataKi:  18.8nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301917( N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimi...)
Affinity DataKi:  19.2nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301877(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  19.2nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301829(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  19.3nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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