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Patent code US9603834

Compile Data Set for Download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309528
PNG
(N-{5-chloro-2-[(2-thienylsulfonyl)amino]phenyl}-1-...)
Show SMILES Clc1ccc(NS(=O)(=O)c2cccs2)c(NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C18H13ClN2O5S3/c19-13-7-8-14(20-29(24,25)18-6-3-9-27-18)15(11-13)21-28(22,23)17-10-12-4-1-2-5-16(12)26-17/h1-11,20-21H
PDB

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US Patent
n/an/a 20n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309524
PNG
(N-{4,5-dichloro-2-[(2-thienylsulfonyl)amino]phenyl...)
Show SMILES Clc1cc(NS(=O)(=O)c2cc3ccccc3o2)c(NS(=O)(=O)c2cccs2)cc1Cl
Show InChI InChI=1S/C18H12Cl2N2O5S3/c19-12-9-14(15(10-13(12)20)22-30(25,26)18-6-3-7-28-18)21-29(23,24)17-8-11-4-1-2-5-16(11)27-17/h1-10,21-22H
PDB

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UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 96n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309527
PNG
(N-{4-chloro-2-[(2-thienylsulfonyl)amino]phenyl}-1-...)
Show SMILES Clc1ccc(NS(=O)(=O)c2cc3ccccc3o2)c(NS(=O)(=O)c2cccs2)c1
Show InChI InChI=1S/C18H13ClN2O5S3/c19-13-7-8-14(15(11-13)21-29(24,25)18-6-3-9-27-18)20-28(22,23)17-10-12-4-1-2-5-16(12)26-17/h1-11,20-21H
PDB

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US Patent
n/an/a 145n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309515
PNG
(N-(5-chloro-2-{[(2,6-difluorophenyl)sulfonyl]amino...)
Show SMILES Fc1cccc(F)c1S(=O)(=O)Nc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C20H13ClF2N2O5S2/c21-13-8-9-16(24-32(28,29)20-14(22)5-3-6-15(20)23)17(11-13)25-31(26,27)19-10-12-4-1-2-7-18(12)30-19/h1-11,24-25H
PDB

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US Patent
n/an/a 153n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309522
PNG
(N-{2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chloroph...)
Show SMILES Cc1n[nH]c(C)c1S(=O)(=O)Nc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
PDB

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n/an/a 183n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309520
PNG
(N-{2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chloroph...)
Show SMILES Cn1ccc(n1)S(=O)(=O)Nc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C18H15ClN4O5S2/c1-23-9-8-17(20-23)29(24,25)21-14-7-6-13(19)11-15(14)22-30(26,27)18-10-12-4-2-3-5-16(12)28-18/h2-11,21-22H,1H3
PDB

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n/an/a 185n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309510
PNG
(N-(4,5-dichloro-2-{[(3-chloro-2-fluorophenyl)sulfo...)
Show SMILES Fc1c(Cl)cccc1S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C16H10Cl3FN2O4S3/c17-9-3-1-4-14(16(9)20)28(23,24)21-12-7-10(18)11(19)8-13(12)22-29(25,26)15-5-2-6-27-15/h1-8,21-22H
PDB

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US Patent
n/an/a 217n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309504
PNG
(US9603834, 3 | methyl 3-[({2-[(1-benzofuran-2-ylsu...)
Show SMILES COC(=O)c1sccc1S(=O)(=O)Nc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C20H15ClN2O7S3/c1-29-20(24)19-17(8-9-31-19)32(25,26)22-14-7-6-13(21)11-15(14)23-33(27,28)18-10-12-4-2-3-5-16(12)30-18/h2-11,22-23H,1H3
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n/an/a 246n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309502
PNG
(5-chloro-N-{4,5-dichloro-2-[(2-thienylsulfonyl)ami...)
Show SMILES Clc1cc(NS(=O)(=O)c2ccco2)c(NS(=O)(=O)c2cccs2)cc1Cl
Show InChI InChI=1S/C14H10Cl2N2O5S3/c15-9-7-11(17-25(19,20)13-3-1-5-23-13)12(8-10(9)16)18-26(21,22)14-4-2-6-24-14/h1-8,17-18H
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n/an/a 263n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309503
PNG
(6-chloro-N-{4,5-dichloro-2-[(2-thienylsulfonyl)ami...)
Show SMILES Clc1ccc(cn1)S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C15H10Cl3N3O4S3/c16-10-6-12(20-27(22,23)9-3-4-14(18)19-8-9)13(7-11(10)17)21-28(24,25)15-2-1-5-26-15/h1-8,20-21H
PDB

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US Patent
n/an/a 281n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309523
PNG
(N-{2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chloroph...)
Show SMILES Cc1nn(C)c(Cl)c1S(=O)(=O)Nc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C19H16Cl2N4O5S2/c1-11-18(19(21)25(2)22-11)32(28,29)23-14-8-7-13(20)10-15(14)24-31(26,27)17-9-12-5-3-4-6-16(12)30-17/h3-10,23-24H,1-2H3
PDB

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n/an/a 294n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309518
PNG
(N-[4,5-dichloro-2-({[3-(trifluoromethyl)phenyl]sul...)
Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C17H11Cl2F3N2O4S3/c18-12-8-14(15(9-13(12)19)24-31(27,28)16-5-2-6-29-16)23-30(25,26)11-4-1-3-10(7-11)17(20,21)22/h1-9,23-24H
PDB

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US Patent
n/an/a 306n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309526
PNG
(N-{4,5-dichloro-2-[(2-thienylsulfonyl)amino]phenyl...)
Show SMILES Cc1ccc(o1)S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C15H12Cl2N2O5S3/c1-9-4-5-14(24-9)26(20,21)18-12-7-10(16)11(17)8-13(12)19-27(22,23)15-3-2-6-25-15/h2-8,18-19H,1H3
PDB

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n/an/a 311n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309516
PNG
(N-(5-chloro-2-{[(5-methyl-2-thienyl)sulfonyl]amino...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C19H15ClN2O5S3/c1-12-6-9-19(28-12)30(25,26)21-15-8-7-14(20)11-16(15)22-29(23,24)18-10-13-4-2-3-5-17(13)27-18/h2-11,21-22H,1H3
PDB

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n/an/a 339n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309517
PNG
(N-[3-({[4-chloro-3-(trifluoromethyl)phenyl]sulfony...)
Show SMILES FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)Nc1cccnc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C16H11ClF3N3O4S3/c17-12-6-5-10(9-11(12)16(18,19)20)29(24,25)22-13-3-1-7-21-15(13)23-30(26,27)14-4-2-8-28-14/h1-9,22H,(H,21,23)
PDB

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n/an/a 349n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309512
PNG
(N-(4,5-dichloro-2-{[(4-chloro-2-fluorophenyl)sulfo...)
Show SMILES Fc1cc(Cl)ccc1S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C16H10Cl3FN2O4S3/c17-9-3-4-15(12(20)6-9)28(23,24)21-13-7-10(18)11(19)8-14(13)22-29(25,26)16-2-1-5-27-16/h1-8,21-22H
PDB

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n/an/a 361n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309510
PNG
(N-(4,5-dichloro-2-{[(3-chloro-2-fluorophenyl)sulfo...)
Show SMILES Fc1c(Cl)cccc1S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C16H10Cl3FN2O4S3/c17-9-3-1-4-14(16(9)20)28(23,24)21-12-7-10(18)11(19)8-13(12)22-29(25,26)15-5-2-6-27-15/h1-8,21-22H
PDB

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n/an/a 391n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309508
PNG
(N-(4,5-dichloro-2-{[(3,4-dichlorophenyl)sulfonyl]a...)
Show SMILES Clc1ccc(cc1Cl)S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C16H10Cl4N2O4S3/c17-10-4-3-9(6-11(10)18)28(23,24)21-14-7-12(19)13(20)8-15(14)22-29(25,26)16-2-1-5-27-16/h1-8,21-22H
PDB

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n/an/a 394n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309507
PNG
(N-(4,5-dichloro-2-{[(2-fluorophenyl)sulfonyl]amino...)
Show SMILES Fc1ccccc1S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C16H11Cl2FN2O4S3/c17-10-8-13(20-27(22,23)15-5-2-1-4-12(15)19)14(9-11(10)18)21-28(24,25)16-6-3-7-26-16/h1-9,20-21H
PDB

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n/an/a 402n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309521
PNG
(N-{2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chloroph...)
Show SMILES Cn1cnc(c1)S(=O)(=O)Nc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C18H15ClN4O5S2/c1-23-10-17(20-11-23)29(24,25)21-14-7-6-13(19)9-15(14)22-30(26,27)18-8-12-4-2-3-5-16(12)28-18/h2-11,21-22H,1H3
PDB

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n/an/a 423n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309519
PNG
(N-[4,5-dichloro-2-({[4-fluoro-3-(trifluoromethyl)p...)
Show SMILES Fc1ccc(cc1C(F)(F)F)S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C17H10Cl2F4N2O4S3/c18-11-7-14(15(8-12(11)19)25-32(28,29)16-2-1-5-30-16)24-31(26,27)9-3-4-13(20)10(6-9)17(21,22)23/h1-8,24-25H
PDB

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PC sid
UniChem
US Patent
n/an/a 432n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309513
PNG
(N-(4,5-dichloro-2-{[(4-fluorophenyl)sulfonyl]amino...)
Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C16H11Cl2FN2O4S3/c17-12-8-14(20-27(22,23)11-5-3-10(19)4-6-11)15(9-13(12)18)21-28(24,25)16-2-1-7-26-16/h1-9,20-21H
PDB

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UniChem
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n/an/a 441n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309506
PNG
(N-(4,5-dichloro-2-{[(2,4-difluorophenyl)sulfonyl]a...)
Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C16H10Cl2F2N2O4S3/c17-10-7-13(21-28(23,24)15-4-3-9(19)6-12(15)20)14(8-11(10)18)22-29(25,26)16-2-1-5-27-16/h1-8,21-22H
PDB

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UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 451n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309505
PNG
(N-(2-{[(4-bromo-3-methylphenyl)sulfonyl]amino}-4,5...)
Show SMILES Cc1cc(ccc1Br)S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C17H13BrCl2N2O4S3/c1-10-7-11(4-5-12(10)18)28(23,24)21-15-8-13(19)14(20)9-16(15)22-29(25,26)17-3-2-6-27-17/h2-9,21-22H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 471n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309514
PNG
(N-(5-chloro-2-{[(2,6-dichlorophenyl)sulfonyl]amino...)
Show SMILES Clc1ccc(NS(=O)(=O)c2c(Cl)cccc2Cl)c(NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C20H13Cl3N2O5S2/c21-13-8-9-16(24-32(28,29)20-14(22)5-3-6-15(20)23)17(11-13)25-31(26,27)19-10-12-4-1-2-7-18(12)30-19/h1-11,24-25H
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 478n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309509
PNG
(N-(4,5-dichloro-2-{[(3,5-dichloro-2-hydroxyphenyl)...)
Show SMILES Oc1c(Cl)cc(Cl)cc1S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C16H10Cl4N2O5S3/c17-8-4-11(20)16(23)14(5-8)29(24,25)21-12-6-9(18)10(19)7-13(12)22-30(26,27)15-2-1-3-28-15/h1-7,21-23H
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 482n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM309525
PNG
(N-{4,5-dichloro-2-[(2-thienylsulfonyl)amino]phenyl...)
Show SMILES Clc1cc(NS(=O)(=O)c2cccs2)c(NS(=O)(=O)c2cc3ccccc3s2)cc1Cl
Show InChI InChI=1S/C18H12Cl2N2O4S4/c19-12-9-14(21-29(23,24)17-6-3-7-27-17)15(10-13(12)20)22-30(25,26)18-8-11-4-1-2-5-16(11)28-18/h1-10,21-22H
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 494n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9603834 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%