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Found 27 Enz. Inhib. hit(s) with all data for entry = 1178
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309528(N-{5-chloro-2-[(2-thienylsulfonyl)amino]phenyl}-1-...)
Affinity DataIC50:  20nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309524(N-{4,5-dichloro-2-[(2-thienylsulfonyl)amino]phenyl...)
Affinity DataIC50:  96nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309527(N-{4-chloro-2-[(2-thienylsulfonyl)amino]phenyl}-1-...)
Affinity DataIC50:  145nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309515(N-(5-chloro-2-{[(2,6-difluorophenyl)sulfonyl]amino...)
Affinity DataIC50:  153nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309522(N-{2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chloroph...)
Affinity DataIC50:  183nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309520(N-{2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chloroph...)
Affinity DataIC50:  185nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309510(N-(4,5-dichloro-2-{[(3-chloro-2-fluorophenyl)sulfo...)
Affinity DataIC50:  217nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309504(US9603834, 3 | methyl 3-[({2-[(1-benzofuran-2-ylsu...)
Affinity DataIC50:  246nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309502(5-chloro-N-{4,5-dichloro-2-[(2-thienylsulfonyl)ami...)
Affinity DataIC50:  263nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309503(6-chloro-N-{4,5-dichloro-2-[(2-thienylsulfonyl)ami...)
Affinity DataIC50:  281nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309523(N-{2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chloroph...)
Affinity DataIC50:  294nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309518(N-[4,5-dichloro-2-({[3-(trifluoromethyl)phenyl]sul...)
Affinity DataIC50:  306nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309526(N-{4,5-dichloro-2-[(2-thienylsulfonyl)amino]phenyl...)
Affinity DataIC50:  311nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309516(N-(5-chloro-2-{[(5-methyl-2-thienyl)sulfonyl]amino...)
Affinity DataIC50:  339nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309517(N-[3-({[4-chloro-3-(trifluoromethyl)phenyl]sulfony...)
Affinity DataIC50:  349nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309512(N-(4,5-dichloro-2-{[(4-chloro-2-fluorophenyl)sulfo...)
Affinity DataIC50:  361nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309510(N-(4,5-dichloro-2-{[(3-chloro-2-fluorophenyl)sulfo...)
Affinity DataIC50:  391nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309508(N-(4,5-dichloro-2-{[(3,4-dichlorophenyl)sulfonyl]a...)
Affinity DataIC50:  394nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309507(N-(4,5-dichloro-2-{[(2-fluorophenyl)sulfonyl]amino...)
Affinity DataIC50:  402nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309521(N-{2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chloroph...)
Affinity DataIC50:  423nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309519(N-[4,5-dichloro-2-({[4-fluoro-3-(trifluoromethyl)p...)
Affinity DataIC50:  432nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309513(N-(4,5-dichloro-2-{[(4-fluorophenyl)sulfonyl]amino...)
Affinity DataIC50:  441nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309506(N-(4,5-dichloro-2-{[(2,4-difluorophenyl)sulfonyl]a...)
Affinity DataIC50:  451nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309505(N-(2-{[(4-bromo-3-methylphenyl)sulfonyl]amino}-4,5...)
Affinity DataIC50:  471nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309514(N-(5-chloro-2-{[(2,6-dichlorophenyl)sulfonyl]amino...)
Affinity DataIC50:  478nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309509(N-(4,5-dichloro-2-{[(3,5-dichloro-2-hydroxyphenyl)...)
Affinity DataIC50:  482nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM309525(N-{4,5-dichloro-2-[(2-thienylsulfonyl)amino]phenyl...)
Affinity DataIC50:  494nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent