Compile Data Set for Download or QSAR
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Found 21 Enz. Inhib. hit(s) with all data for entry = 1291
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314731(US9611270, Example 21)
Affinity DataIC50:  1nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314735(US9611270, Example 32)
Affinity DataIC50:  3nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM50358201(CHEMBL1921976 | US9611270, orteronel)
Affinity DataIC50:  4nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM50358201(CHEMBL1921976 | US9611270, orteronel)
Affinity DataIC50:  4nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314733(US9611270, Example 30)
Affinity DataIC50:  5nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314740(US9611270, Example 42)
Affinity DataIC50:  8nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314736(US9611270, Example 33)
Affinity DataIC50:  10nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314740(US9611270, Example 42)
Affinity DataIC50:  120nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  130nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314736(US9611270, Example 33)
Affinity DataIC50:  150nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314738(US9611270, Example 38)
Affinity DataIC50:  174nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314739(US9611270, Example 39 | US9611270, Example 41)
Affinity DataIC50:  183nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314734(US9611270, Example 31)
Affinity DataIC50:  199nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314732(US9611270, Example 29)
Affinity DataIC50:  208nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314737(US9611270, Example 37)
Affinity DataIC50:  244nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM50435990(GALETERONE | TOK-001 | US9611270, galaterone | VN/...)
Affinity DataIC50:  248nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM50435990(GALETERONE | TOK-001 | US9611270, galaterone | VN/...)
Affinity DataIC50:  282nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  296nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314730(US9611270, Example 8)
Affinity DataIC50:  428nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314738(US9611270, Example 38)
Affinity DataIC50:  537nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM314739(US9611270, Example 39 | US9611270, Example 41)
Affinity DataIC50:  831nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent