BindingDB logo
myBDB logout

Patent code US9617239

Compile Data Set for Download or QSAR
Found 89 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316366
PNG
(US9617239, BRITE-354972)
Show SMILES Cc1ccc(Oc2ccc(s2)S(=O)(=O)NCc2cccc3ccccc23)cc1
Show InChI InChI=1S/C22H19NO3S2/c1-16-9-11-19(12-10-16)26-21-13-14-22(27-21)28(24,25)23-15-18-7-4-6-17-5-2-3-8-20(17)18/h2-14,23H,15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<1n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316459
PNG
(US9617239, BRITE-492802)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccc(Cl)cc1
Show InChI InChI=1S/C21H21Cl2N3O3S2/c22-16-6-4-15(5-7-16)14-25-31(27,28)20-13-19(23)21(30-20)29-18-3-1-2-17(12-18)26-10-8-24-9-11-26/h1-7,12-13,24-25H,8-11,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316467
PNG
(US9617239, BRITE-492808)
Show SMILES Cc1cccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1
Show InChI InChI=1S/C22H24ClN3O3S2/c1-16-4-2-5-17(12-16)15-25-31(27,28)21-14-20(23)22(30-21)29-19-7-3-6-18(13-19)26-10-8-24-9-11-26/h2-7,12-14,24-25H,8-11,15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316468
PNG
(US9617239, BRITE-492809)
Show SMILES Fc1cccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1
Show InChI InChI=1S/C21H21ClFN3O3S2/c22-19-13-20(31(27,28)25-14-15-3-1-4-16(23)11-15)30-21(19)29-18-6-2-5-17(12-18)26-9-7-24-8-10-26/h1-6,11-13,24-25H,7-10,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 40n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316461
PNG
(US9617239, BRITE-492805)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccccc1Cl
Show InChI InChI=1S/C21H21Cl2N3O3S2/c22-18-7-2-1-4-15(18)14-25-31(27,28)20-13-19(23)21(30-20)29-17-6-3-5-16(12-17)26-10-8-24-9-11-26/h1-7,12-13,24-25H,8-11,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 40n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316457
PNG
(US9617239, BRITE-492800)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C20H19Cl2N3O3S2/c21-14-3-1-4-15(11-14)24-30(26,27)19-13-18(22)20(29-19)28-17-6-2-5-16(12-17)25-9-7-23-8-10-25/h1-6,11-13,23-24H,7-10H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 70n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316456
PNG
(US9617239, BRITE-492799)
Show SMILES COc1cccc(NS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1
Show InChI InChI=1S/C21H22ClN3O4S2/c1-28-17-6-2-4-15(12-17)24-31(26,27)20-14-19(22)21(30-20)29-18-7-3-5-16(13-18)25-10-8-23-9-11-25/h2-7,12-14,23-24H,8-11H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 70n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316367
PNG
(US9617239, BRITE-355123)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1cccc(Cl)c1
Show InChI InChI=1S/C21H21Cl2N3O3S2/c22-16-4-1-3-15(11-16)14-25-31(27,28)20-13-19(23)21(30-20)29-18-6-2-5-17(12-18)26-9-7-24-8-10-26/h1-6,11-13,24-25H,7-10,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 90n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316368
PNG
(US9617239, BRITE-355252)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C25H24ClN3O3S2/c26-23-16-24(34(30,31)28-17-19-7-3-6-18-5-1-2-10-22(18)19)33-25(23)32-21-9-4-8-20(15-21)29-13-11-27-12-14-29/h1-10,15-16,27-28H,11-14,17H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 90n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316454
PNG
(US9617239, BRITE-492797)
Show SMILES O=S(=O)(NCc1cccc2ccccc12)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C25H25N3O3S2/c29-33(30,27-18-20-7-3-6-19-5-1-2-10-23(19)20)25-12-11-24(32-25)31-22-9-4-8-21(17-22)28-15-13-26-14-16-28/h1-12,17,26-27H,13-16,18H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 90n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316460
PNG
(US9617239, BRITE-492803)
Show SMILES COc1ccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)cc1
Show InChI InChI=1S/C22H24ClN3O4S2/c1-29-18-7-5-16(6-8-18)15-25-32(27,28)21-14-20(23)22(31-21)30-19-4-2-3-17(13-19)26-11-9-24-10-12-26/h2-8,13-14,24-25H,9-12,15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 100n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316369
PNG
(US9617239, BRITE-354975)
Show SMILES O=S(=O)(NCCN1CCCC1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C20H28N4O3S2/c25-29(26,22-10-13-23-11-1-2-12-23)20-7-6-19(28-20)27-18-5-3-4-17(16-18)24-14-8-21-9-15-24/h3-7,16,21-22H,1-2,8-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 120n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316453
PNG
(US9617239, BRITE-492796)
Show SMILES CN(Cc1cccc2ccccc12)S(=O)(=O)c1cc(Cl)c(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C26H26ClN3O3S2/c1-29(18-20-8-4-7-19-6-2-3-11-23(19)20)35(31,32)25-17-24(27)26(34-25)33-22-10-5-9-21(16-22)30-14-12-28-13-15-30/h2-11,16-17,28H,12-15,18H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 120n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316466
PNG
(US9617239, BRITE-492807)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C21H20Cl3N3O3S2/c22-15-8-14(9-16(23)10-15)13-26-32(28,29)20-12-19(24)21(31-20)30-18-3-1-2-17(11-18)27-6-4-25-5-7-27/h1-3,8-12,25-26H,4-7,13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 130n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316370
PNG
(US9617239, BRITE-354989)
Show SMILES CN(C)CCCNS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C19H28N4O3S2/c1-22(2)12-4-9-21-28(24,25)19-8-7-18(27-19)26-17-6-3-5-16(15-17)23-13-10-20-11-14-23/h3,5-8,15,20-21H,4,9-14H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316371
PNG
(US9617239, BRITE-354909)
Show SMILES COc1ccc(NS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)cc1
Show InChI InChI=1S/C21H22ClN3O4S2/c1-28-17-7-5-15(6-8-17)24-31(26,27)20-14-19(22)21(30-20)29-18-4-2-3-16(13-18)25-11-9-23-10-12-25/h2-8,13-14,23-24H,9-12H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 170n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316372
PNG
(US9617239, BRITE-354725)
Show SMILES COc1ccc(CCNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)cc1OC
Show InChI InChI=1S/C24H28ClN3O5S2/c1-31-21-7-6-17(14-22(21)32-2)8-9-27-35(29,30)23-16-20(25)24(34-23)33-19-5-3-4-18(15-19)28-12-10-26-11-13-28/h3-7,14-16,26-27H,8-13H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 190n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316373
PNG
(US9617239, BRITE-354969)
Show SMILES CCN(CCNS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1)c1cccc(C)c1
Show InChI InChI=1S/C25H32N4O3S2/c1-3-28(21-7-4-6-20(2)18-21)17-14-27-34(30,31)25-11-10-24(33-25)32-23-9-5-8-22(19-23)29-15-12-26-13-16-29/h4-11,18-19,26-27H,3,12-17H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 200n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316375
PNG
(US9617239, BRITE-355006)
Show SMILES Cc1ccc(CNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)c(C)c1
Show InChI InChI=1S/C23H27N3O3S2/c1-17-6-7-19(18(2)14-17)16-25-31(27,28)23-9-8-22(30-23)29-21-5-3-4-20(15-21)26-12-10-24-11-13-26/h3-9,14-15,24-25H,10-13,16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 210n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316374
PNG
(US9617239, BRITE-355417)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccccc1Br
Show InChI InChI=1S/C21H21BrClN3O3S2/c22-18-7-2-1-4-15(18)14-25-31(27,28)20-13-19(23)21(30-20)29-17-6-3-5-16(12-17)26-10-8-24-9-11-26/h1-7,12-13,24-25H,8-11,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 210n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316376
PNG
(US9617239, BRITE-355017)
Show SMILES O=S(=O)(NCc1ccc2OCOc2c1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C22H23N3O5S2/c26-32(27,24-14-16-4-5-19-20(12-16)29-15-28-19)22-7-6-21(31-22)30-18-3-1-2-17(13-18)25-10-8-23-9-11-25/h1-7,12-13,23-24H,8-11,14-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 220n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316377
PNG
(US9617239, BRITE-354979)
Show SMILES COc1ccc(NS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)cc1
Show InChI InChI=1S/C21H23N3O4S2/c1-27-18-7-5-16(6-8-18)23-30(25,26)21-10-9-20(29-21)28-19-4-2-3-17(15-19)24-13-11-22-12-14-24/h2-10,15,22-23H,11-14H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 230n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316378
PNG
(US9617239, BRITE-355004)
Show SMILES Clc1ccc(CCNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)cc1
Show InChI InChI=1S/C22H24ClN3O3S2/c23-18-6-4-17(5-7-18)10-11-25-31(27,28)22-9-8-21(30-22)29-20-3-1-2-19(16-20)26-14-12-24-13-15-26/h1-9,16,24-25H,10-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 240n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316379
PNG
(US9617239, BRITE-354667)
Show SMILES Fc1ccccc1CCNS(=O)(=O)c1cc(Cl)c(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C22H23ClFN3O3S2/c23-19-15-21(32(28,29)26-9-8-16-4-1-2-7-20(16)24)31-22(19)30-18-6-3-5-17(14-18)27-12-10-25-11-13-27/h1-7,14-15,25-26H,8-13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 270n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316380
PNG
(US9617239, BRITE-354966)
Show SMILES O=S(=O)(NCC1CCCCC1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C21H29N3O3S2/c25-29(26,23-16-17-5-2-1-3-6-17)21-10-9-20(28-21)27-19-8-4-7-18(15-19)24-13-11-22-12-14-24/h4,7-10,15,17,22-23H,1-3,5-6,11-14,16H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 270n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316381
PNG
(US9617239, BRITE-355262)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccccc1
Show InChI InChI=1S/C21H22ClN3O3S2/c22-19-14-20(30(26,27)24-15-16-5-2-1-3-6-16)29-21(19)28-18-8-4-7-17(13-18)25-11-9-23-10-12-25/h1-8,13-14,23-24H,9-12,15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 280n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316383
PNG
(US9617239, BRITE-354873)
Show SMILES FC(F)(F)c1cccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1
Show InChI InChI=1S/C22H21ClF3N3O3S2/c23-19-13-20(34(30,31)28-14-15-3-1-4-16(11-15)22(24,25)26)33-21(19)32-18-6-2-5-17(12-18)29-9-7-27-8-10-29/h1-6,11-13,27-28H,7-10,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 290n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316382
PNG
(US9617239, BRITE-354965)
Show SMILES COc1ccc(CNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)cc1OC
Show InChI InChI=1S/C23H27N3O5S2/c1-29-20-7-6-17(14-21(20)30-2)16-25-33(27,28)23-9-8-22(32-23)31-19-5-3-4-18(15-19)26-12-10-24-11-13-26/h3-9,14-15,24-25H,10-13,16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 290n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316462
PNG
(US9617239, BRITE-492806)
Show SMILES Clc1cc(sc1Oc1ccc(cc1)N1CCNCC1)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C25H24ClN3O3S2/c26-23-16-24(34(30,31)28-17-19-6-3-5-18-4-1-2-7-22(18)19)33-25(23)32-21-10-8-20(9-11-21)29-14-12-27-13-15-29/h1-11,16,27-28H,12-15,17H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 300n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316384
PNG
(US9617239, BRITE-354615)
Show SMILES COc1cc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)cc(OC)c1
Show InChI InChI=1S/C23H26ClN3O5S2/c1-30-19-10-16(11-20(13-19)31-2)15-26-34(28,29)22-14-21(24)23(33-22)32-18-5-3-4-17(12-18)27-8-6-25-7-9-27/h3-5,10-14,25-26H,6-9,15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 310n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316385
PNG
(US9617239, BRITE-355016)
Show SMILES O=C1CCCN1CCCNS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C21H28N4O4S2/c26-19-6-2-12-25(19)13-3-9-23-31(27,28)21-8-7-20(30-21)29-18-5-1-4-17(16-18)24-14-10-22-11-15-24/h1,4-5,7-8,16,22-23H,2-3,6,9-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 320n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316386
PNG
(US9617239, BRITE-354517)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccc2OCOc2c1
Show InChI InChI=1S/C22H22ClN3O5S2/c23-18-12-21(33(27,28)25-13-15-4-5-19-20(10-15)30-14-29-19)32-22(18)31-17-3-1-2-16(11-17)26-8-6-24-7-9-26/h1-5,10-12,24-25H,6-9,13-14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 320n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316387
PNG
(US9617239, BRITE-354958)
Show SMILES Fc1ccccc1CCNS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C22H24FN3O3S2/c23-20-7-2-1-4-17(20)10-11-25-31(27,28)22-9-8-21(30-22)29-19-6-3-5-18(16-19)26-14-12-24-13-15-26/h1-9,16,24-25H,10-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 330n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316455
PNG
(US9617239, BRITE-492798)
Show SMILES NS(=O)(=O)c1cc(Cl)c(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C14H16ClN3O3S2/c15-12-9-13(23(16,19)20)22-14(12)21-11-3-1-2-10(8-11)18-6-4-17-5-7-18/h1-3,8-9,17H,4-7H2,(H2,16,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 330n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316388
PNG
(US9617239, BRITE-355360)
Show SMILES COc1ccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)cc1OC
Show InChI InChI=1S/C23H26ClN3O5S2/c1-30-20-7-6-16(12-21(20)31-2)15-26-34(28,29)22-14-19(24)23(33-22)32-18-5-3-4-17(13-18)27-10-8-25-9-11-27/h3-7,12-14,25-26H,8-11,15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 340n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316389
PNG
(US9617239, BRITE-355227)
Show SMILES COc1cccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1
Show InChI InChI=1S/C22H24ClN3O4S2/c1-29-18-6-2-4-16(12-18)15-25-32(27,28)21-14-20(23)22(31-21)30-19-7-3-5-17(13-19)26-10-8-24-9-11-26/h2-7,12-14,24-25H,8-11,15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 350n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316394
PNG
(US9617239, BRITE-354948)
Show SMILES CSCCCNS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C18H25N3O3S3/c1-25-13-3-8-20-27(22,23)18-7-6-17(26-18)24-16-5-2-4-15(14-16)21-11-9-19-10-12-21/h2,4-7,14,19-20H,3,8-13H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 390n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316395
PNG
(US9617239, BRITE-355336)
Show SMILES Cc1ccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c(C)c1
Show InChI InChI=1S/C23H26ClN3O3S2/c1-16-6-7-18(17(2)12-16)15-26-32(28,29)22-14-21(24)23(31-22)30-20-5-3-4-19(13-20)27-10-8-25-9-11-27/h3-7,12-14,25-26H,8-11,15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 410n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316396
PNG
(US9617239, BRITE-355423)
Show SMILES CC(CCc1ccccc1)NS(=O)(=O)c1cc(Cl)c(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C24H28ClN3O3S2/c1-18(10-11-19-6-3-2-4-7-19)27-33(29,30)23-17-22(25)24(32-23)31-21-9-5-8-20(16-21)28-14-12-26-13-15-28/h2-9,16-18,26-27H,10-15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 430n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316397
PNG
(US9617239, BRITE-355468)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCCc1ccc(Cl)cc1
Show InChI InChI=1S/C22H23Cl2N3O3S2/c23-17-6-4-16(5-7-17)8-9-26-32(28,29)21-15-20(24)22(31-21)30-19-3-1-2-18(14-19)27-12-10-25-11-13-27/h1-7,14-15,25-26H,8-13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 500n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316399
PNG
(US9617239, BRITE-355003)
Show SMILES COc1ccc(CCNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)cc1
Show InChI InChI=1S/C23H27N3O4S2/c1-29-20-7-5-18(6-8-20)11-12-25-32(27,28)23-10-9-22(31-23)30-21-4-2-3-19(17-21)26-15-13-24-14-16-26/h2-10,17,24-25H,11-16H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 510n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316398
PNG
(US9617239, BRITE-355202)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NC1CCCC1
Show InChI InChI=1S/C19H24ClN3O3S2/c20-17-13-18(28(24,25)22-14-4-1-2-5-14)27-19(17)26-16-7-3-6-15(12-16)23-10-8-21-9-11-23/h3,6-7,12-14,21-22H,1-2,4-5,8-11H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 510n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316400
PNG
(US9617239, BRITE-354946)
Show SMILES O=S(=O)(NC1CCCCCC1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C21H29N3O3S2/c25-29(26,23-17-6-3-1-2-4-7-17)21-11-10-20(28-21)27-19-9-5-8-18(16-19)24-14-12-22-13-15-24/h5,8-11,16-17,22-23H,1-4,6-7,12-15H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 560n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316401
PNG
(US9617239, BRITE-354983)
Show SMILES COc1cccc(CNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)c1
Show InChI InChI=1S/C22H25N3O4S2/c1-28-19-6-2-4-17(14-19)16-24-31(26,27)22-9-8-21(30-22)29-20-7-3-5-18(15-20)25-12-10-23-11-13-25/h2-9,14-15,23-24H,10-13,16H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 570n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316402
PNG
(US9617239, BRITE-355014)
Show SMILES O=S(=O)(NCc1cccs1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C19H21N3O3S3/c23-28(24,21-14-17-5-2-12-26-17)19-7-6-18(27-19)25-16-4-1-3-15(13-16)22-10-8-20-9-11-22/h1-7,12-13,20-21H,8-11,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 600n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316403
PNG
(US9617239, BRITE-355015)
Show SMILES O=S(=O)(NCCc1cccs1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C20H23N3O3S3/c24-29(25,22-9-8-18-5-2-14-27-18)20-7-6-19(28-20)26-17-4-1-3-16(15-17)23-12-10-21-11-13-23/h1-7,14-15,21-22H,8-13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 630n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316404
PNG
(US9617239, BRITE-354627)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCC1CCCO1
Show InChI InChI=1S/C19H24ClN3O4S2/c20-17-12-18(29(24,25)22-13-16-5-2-10-26-16)28-19(17)27-15-4-1-3-14(11-15)23-8-6-21-7-9-23/h1,3-4,11-12,16,21-22H,2,5-10,13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 710n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316406
PNG
(US9617239, BRITE-354764)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCCCN1CCCC1=O
Show InChI InChI=1S/C21H27ClN4O4S2/c22-18-15-20(32(28,29)24-7-3-11-26-10-2-6-19(26)27)31-21(18)30-17-5-1-4-16(14-17)25-12-8-23-9-13-25/h1,4-5,14-15,23-24H,2-3,6-13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 730n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316407
PNG
(US9617239, BRITE-354993)
Show SMILES CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C22H30N4O5S2/c1-2-30-22(27)26-12-8-17(9-13-26)24-33(28,29)21-7-6-20(32-21)31-19-5-3-4-18(16-19)25-14-10-23-11-15-25/h3-7,16-17,23-24H,2,8-15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 730n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316409
PNG
(US9617239, BRITE-354984)
Show SMILES CC(CCc1ccccc1)NS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C24H29N3O3S2/c1-19(10-11-20-6-3-2-4-7-20)26-32(28,29)24-13-12-23(31-24)30-22-9-5-8-21(18-22)27-16-14-25-15-17-27/h2-9,12-13,18-19,25-26H,10-11,14-17H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 750n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316408
PNG
(US9617239, BRITE-354956)
Show SMILES O=S(=O)(NC1CCCCC1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C20H27N3O3S2/c24-28(25,22-16-5-2-1-3-6-16)20-10-9-19(27-20)26-18-8-4-7-17(15-18)23-13-11-21-12-14-23/h4,7-10,15-16,21-22H,1-3,5-6,11-14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 750n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316410
PNG
(US9617239, BRITE-354974)
Show SMILES CC(NS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1)C1CCCCC1
Show InChI InChI=1S/C22H31N3O3S2/c1-17(18-6-3-2-4-7-18)24-30(26,27)22-11-10-21(29-22)28-20-9-5-8-19(16-20)25-14-12-23-13-15-25/h5,8-11,16-18,23-24H,2-4,6-7,12-15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 760n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316411
PNG
(US9617239, BRITE-354947)
Show SMILES O=S(=O)(NC1CCCC1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C19H25N3O3S2/c23-27(24,21-15-4-1-2-5-15)19-9-8-18(26-19)25-17-7-3-6-16(14-17)22-12-10-20-11-13-22/h3,6-9,14-15,20-21H,1-2,4-5,10-13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 770n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316412
PNG
(US9617239, BRITE-354392)
Show SMILES CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1cc(Cl)c(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C22H29ClN4O5S2/c1-2-31-22(28)27-10-6-16(7-11-27)25-34(29,30)20-15-19(23)21(33-20)32-18-5-3-4-17(14-18)26-12-8-24-9-13-26/h3-5,14-16,24-25H,2,6-13H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 790n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316413
PNG
(US9617239, BRITE-355045)
Show SMILES FC(F)(F)c1ccccc1CNS(=O)(=O)c1cc(Cl)c(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C22H21ClF3N3O3S2/c23-19-13-20(34(30,31)28-14-15-4-1-2-7-18(15)22(24,25)26)33-21(19)32-17-6-3-5-16(12-17)29-10-8-27-9-11-29/h1-7,12-13,27-28H,8-11,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 880n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316414
PNG
(US9617239, BRITE-354994)
Show SMILES CC1(C)CC(CC(C)(C)N1)NS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C23H34N4O3S2/c1-22(2)15-17(16-23(3,4)26-22)25-32(28,29)21-9-8-20(31-21)30-19-7-5-6-18(14-19)27-12-10-24-11-13-27/h5-9,14,17,24-26H,10-13,15-16H2,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 900n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316415
PNG
(US9617239, BRITE-354957)
Show SMILES O=S(=O)(NC1CC1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C17H21N3O3S2/c21-25(22,19-13-4-5-13)17-7-6-16(24-17)23-15-3-1-2-14(12-15)20-10-8-18-9-11-20/h1-3,6-7,12-13,18-19H,4-5,8-11H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 920n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316416
PNG
(US9617239, BRITE-355074)
Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NC1CC1
Show InChI InChI=1S/C17H20ClN3O3S2/c18-15-11-16(26(22,23)20-12-4-5-12)25-17(15)24-14-3-1-2-13(10-14)21-8-6-19-7-9-21/h1-3,10-12,19-20H,4-9H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 970n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316417
PNG
(US9617239, BRITE-354565)
Show SMILES COCCNS(=O)(=O)c1cc(Cl)c(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C17H22ClN3O4S2/c1-24-10-7-20-27(22,23)16-12-15(18)17(26-16)25-14-4-2-3-13(11-14)21-8-5-19-6-9-21/h2-4,11-12,19-20H,5-10H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+3n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316418
PNG
(US9617239, BRITE-354998)
Show SMILES CC(C)C(C)NS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C19H27N3O3S2/c1-14(2)15(3)21-27(23,24)19-8-7-18(26-19)25-17-6-4-5-16(13-17)22-11-9-20-10-12-22/h4-8,13-15,20-21H,9-12H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+3n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316419
PNG
(US9617239, BRITE-354955 | US9617239, BRITE-355296)
Show SMILES O=S(=O)(NCC1CCCO1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C19H25N3O4S2/c23-28(24,21-14-17-5-2-12-25-17)19-7-6-18(27-19)26-16-4-1-3-15(13-16)22-10-8-20-9-11-22/h1,3-4,6-7,13,17,20-21H,2,5,8-12,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.31E+3n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316419
PNG
(US9617239, BRITE-354955 | US9617239, BRITE-355296)
Show SMILES O=S(=O)(NCC1CCCO1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C19H25N3O4S2/c23-28(24,21-14-17-5-2-12-25-17)19-7-6-18(27-19)26-16-4-1-3-15(13-16)22-10-8-20-9-11-22/h1,3-4,6-7,13,17,20-21H,2,5,8-12,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.37E+3n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316423
PNG
(US9617239, BRITE-355008)
Show SMILES CCOCCNS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1
Show InChI InChI=1S/C18H25N3O4S2/c1-2-24-13-10-20-27(22,23)18-7-6-17(26-18)25-16-5-3-4-15(14-16)21-11-8-19-9-12-21/h3-7,14,19-20H,2,8-13H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.39E+3n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316424
PNG
(US9617239, BRITE-355005)
Show SMILES Clc1ccc(CNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)cc1Cl
Show InChI InChI=1S/C21H21Cl2N3O3S2/c22-18-5-4-15(12-19(18)23)14-25-31(27,28)21-7-6-20(30-21)29-17-3-1-2-16(13-17)26-10-8-24-9-11-26/h1-7,12-13,24-25H,8-11,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.70E+3n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316452
PNG
(US9617239, BRITE-492794)
Show SMILES CN1CCN(CC1)c1cccc(Oc2sc(cc2Cl)S(=O)(=O)NCc2cccc3ccccc23)c1
Show InChI InChI=1S/C26H26ClN3O3S2/c1-29-12-14-30(15-13-29)21-9-5-10-22(16-21)33-26-24(27)17-25(34-26)35(31,32)28-18-20-8-4-7-19-6-2-3-11-23(19)20/h2-11,16-17,28H,12-15,18H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.02E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316425
PNG
(US9617239, BRITE-355192)
Show SMILES Clc1cc(sc1Sc1ccccn1)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C20H15ClN2O2S3/c21-17-12-19(27-20(17)26-18-10-3-4-11-22-18)28(24,25)23-13-15-8-5-7-14-6-1-2-9-16(14)15/h1-12,23H,13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.61E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316426
PNG
(US9617239, BRITE-354839)
Show SMILES O=S(=O)(NCc1cccc2ccccc12)c1ccc(Sc2ccccn2)s1
Show InChI InChI=1S/C20H16N2O2S3/c23-27(24,20-12-11-19(26-20)25-18-10-3-4-13-21-18)22-14-16-8-5-7-15-6-1-2-9-17(15)16/h1-13,22H,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316427
PNG
(US9617239, BRITE-354428)
Show SMILES CCCCN(CCCC)c1cccc(Oc2ccc(s2)S(=O)(=O)NCc2cccc3ccccc23)c1
Show InChI InChI=1S/C29H34N2O3S2/c1-3-5-19-31(20-6-4-2)25-14-10-15-26(21-25)34-28-17-18-29(35-28)36(32,33)30-22-24-13-9-12-23-11-7-8-16-27(23)24/h7-18,21,30H,3-6,19-20,22H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.06E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316428
PNG
(US9617239, BRITE-355224)
Show SMILES Clc1cc(sc1Sc1nc2ccccc2o1)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C22H15ClN2O3S3/c23-17-12-20(29-21(17)30-22-25-18-10-3-4-11-19(18)28-22)31(26,27)24-13-15-8-5-7-14-6-1-2-9-16(14)15/h1-12,24H,13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.29E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316429
PNG
(US9617239, BRITE-355018)
Show SMILES CSc1ccc(Oc2ccc(s2)S(=O)(=O)NCc2cccc3ccccc23)cc1C
Show InChI InChI=1S/C23H21NO3S3/c1-16-14-19(10-11-21(16)28-2)27-22-12-13-23(29-22)30(25,26)24-15-18-8-5-7-17-6-3-4-9-20(17)18/h3-14,24H,15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.33E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316430
PNG
(US9617239, BRITE-355240)
Show SMILES Clc1cc(sc1Sc1ccncc1)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C20H15ClN2O2S3/c21-18-12-19(27-20(18)26-16-8-10-22-11-9-16)28(24,25)23-13-15-6-3-5-14-4-1-2-7-17(14)15/h1-12,23H,13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.86E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316431
PNG
(US9617239, BRITE-355329)
Show SMILES Cn1ccnc1Sc1sc(cc1Cl)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C19H16ClN3O2S3/c1-23-10-9-21-19(23)27-18-16(20)11-17(26-18)28(24,25)22-12-14-7-4-6-13-5-2-3-8-15(13)14/h2-11,22H,12H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.15E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316432
PNG
(US9617239, BRITE-355250)
Show SMILES CCN(CC)c1cccc(Oc2sc(cc2Cl)S(=O)(=O)NCc2cccc3ccccc23)c1
Show InChI InChI=1S/C25H25ClN2O3S2/c1-3-28(4-2)20-12-8-13-21(15-20)31-25-23(26)16-24(32-25)33(29,30)27-17-19-11-7-10-18-9-5-6-14-22(18)19/h5-16,27H,3-4,17H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.01E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316433
PNG
(US9617239, BRITE-355339)
Show SMILES CCc1ccc(Oc2sc(cc2Cl)S(=O)(=O)NCc2cccc3ccccc23)cc1
Show InChI InChI=1S/C23H20ClNO3S2/c1-2-16-10-12-19(13-11-16)28-23-21(24)14-22(29-23)30(26,27)25-15-18-8-5-7-17-6-3-4-9-20(17)18/h3-14,25H,2,15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.66E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316434
PNG
(US9617239, BRITE-355319)
Show SMILES Cc1nc2cc(Oc3sc(cc3Cl)S(=O)(=O)NCc3cccc4ccccc34)ccc2s1
Show InChI InChI=1S/C23H17ClN2O3S3/c1-14-26-20-11-17(9-10-21(20)30-14)29-23-19(24)12-22(31-23)32(27,28)25-13-16-7-4-6-15-5-2-3-8-18(15)16/h2-12,25H,13H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.46E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316435
PNG
(US9617239, BRITE-355243)
Show SMILES OCCCc1ccc(Oc2sc(cc2Cl)S(=O)(=O)NCc2cccc3ccccc23)cc1
Show InChI InChI=1S/C24H22ClNO4S2/c25-22-15-23(31-24(22)30-20-12-10-17(11-13-20)5-4-14-27)32(28,29)26-16-19-8-3-7-18-6-1-2-9-21(18)19/h1-3,6-13,15,26-27H,4-5,14,16H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.28E+4n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316436
PNG
(US9617239, BRITE-355180)
Show SMILES Clc1cc(sc1Oc1cccc(c1)-c1ccccc1)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C27H20ClNO3S2/c28-25-17-26(34(30,31)29-18-22-13-6-11-20-10-4-5-15-24(20)22)33-27(25)32-23-14-7-12-21(16-23)19-8-2-1-3-9-19/h1-17,29H,18H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.02E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316437
PNG
(US9617239, BRITE-355244)
Show SMILES Clc1cc(sc1Oc1ccc2CCCCc2c1)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C25H22ClNO3S2/c26-23-15-24(31-25(23)30-21-13-12-17-6-1-2-8-19(17)14-21)32(28,29)27-16-20-10-5-9-18-7-3-4-11-22(18)20/h3-5,7,9-15,27H,1-2,6,8,16H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.23E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316438
PNG
(US9617239, BRITE-355214)
Show SMILES CC(C)c1cc(C)cc(Oc2sc(cc2Cl)S(=O)(=O)NCc2cccc3ccccc23)c1
Show InChI InChI=1S/C25H24ClNO3S2/c1-16(2)20-11-17(3)12-21(13-20)30-25-23(26)14-24(31-25)32(28,29)27-15-19-9-6-8-18-7-4-5-10-22(18)19/h4-14,16,27H,15H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.35E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316441
PNG
(US9617239, BRITE-355030)
Show SMILES O=S(=O)(NCc1cccc2ccccc12)c1ccc(Oc2ccc3CCCCc3c2)s1
Show InChI InChI=1S/C25H23NO3S2/c27-31(28,26-17-21-10-5-9-19-7-3-4-11-23(19)21)25-15-14-24(30-25)29-22-13-12-18-6-1-2-8-20(18)16-22/h3-5,7,9-16,26H,1-2,6,8,17H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.49E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316442
PNG
(US9617239, BRITE-355234)
Show SMILES Cc1cc(C)cc(Oc2sc(cc2Cl)S(=O)(=O)NCc2cccc3ccccc23)c1
Show InChI InChI=1S/C23H20ClNO3S2/c1-15-10-16(2)12-19(11-15)28-23-21(24)13-22(29-23)30(26,27)25-14-18-8-5-7-17-6-3-4-9-20(17)18/h3-13,25H,14H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.52E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316444
PNG
(US9617239, BRITE-355169)
Show SMILES O=S(=O)(NCc1cccc2ccccc12)c1ccc(Oc2ccc(OCc3ccccc3)cc2)s1
Show InChI InChI=1S/C28H23NO4S2/c30-35(31,29-19-23-11-6-10-22-9-4-5-12-26(22)23)28-18-17-27(34-28)33-25-15-13-24(14-16-25)32-20-21-7-2-1-3-8-21/h1-18,29H,19-20H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.53E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316445
PNG
(US9617239, BRITE-354458)
Show SMILES COc1ccc2ccc(Oc3ccc(s3)S(=O)(=O)NCc3cccc4ccccc34)cc2c1
Show InChI InChI=1S/C26H21NO4S2/c1-30-22-11-9-18-10-12-23(16-21(18)15-22)31-25-13-14-26(32-25)33(28,29)27-17-20-7-4-6-19-5-2-3-8-24(19)20/h2-16,27H,17H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.75E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316446
PNG
(US9617239, BRITE-355211)
Show SMILES Clc1cc(sc1Oc1cccnc1)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C20H15ClN2O3S2/c21-18-11-19(27-20(18)26-16-8-4-10-22-13-16)28(24,25)23-12-15-7-3-6-14-5-1-2-9-17(14)15/h1-11,13,23H,12H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.92E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316447
PNG
(US9617239, BRITE-355201)
Show SMILES COc1cccc(OC)c1Oc1sc(cc1Cl)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C23H20ClNO5S2/c1-28-19-11-6-12-20(29-2)22(19)30-23-18(24)13-21(31-23)32(26,27)25-14-16-9-5-8-15-7-3-4-10-17(15)16/h3-13,25H,14H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.02E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316448
PNG
(US9617239, BRITE-355233)
Show SMILES Clc1cc(sc1Oc1ccc2OCOc2c1)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C22H16ClNO5S2/c23-18-11-21(30-22(18)29-16-8-9-19-20(10-16)28-13-27-19)31(25,26)24-12-15-6-3-5-14-4-1-2-7-17(14)15/h1-11,24H,12-13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.76E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316449
PNG
(US9617239, BRITE-355221)
Show SMILES CCCOc1ccc(Oc2sc(cc2Cl)S(=O)(=O)NCc2cccc3ccccc23)cc1
Show InChI InChI=1S/C24H22ClNO4S2/c1-2-14-29-19-10-12-20(13-11-19)30-24-22(25)15-23(31-24)32(27,28)26-16-18-8-5-7-17-6-3-4-9-21(17)18/h3-13,15,26H,2,14,16H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.02E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316450
PNG
(US9617239, BRITE-355253)
Show SMILES Clc1cc(sc1Oc1ccccc1)S(=O)(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C21H16ClNO3S2/c22-19-13-20(27-21(19)26-17-10-2-1-3-11-17)28(24,25)23-14-16-9-6-8-15-7-4-5-12-18(15)16/h1-13,23H,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.44E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM316451
PNG
(US9617239, BRITE-354502)
Show SMILES CC1(C)Cc2cccc(Oc3ccc(s3)S(=O)(=O)NCc3cccc4ccccc34)c2O1
Show InChI InChI=1S/C25H23NO4S2/c1-25(2)15-18-9-6-12-21(24(18)30-25)29-22-13-14-23(31-22)32(27,28)26-16-19-10-5-8-17-7-3-4-11-20(17)19/h3-14,26H,15-16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.65E+5n/an/an/an/an/an/a



North Carolina Central University; The University of North Carolina at Chapel Hill

US Patent


Assay Description
The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...


US Patent US9617239 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%