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Patent code US9624194

Compile Data Set for Download or QSAR
Found 25 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190560
PNG
(US9181185, 15 | US9624194, Compound 15)
Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(c(c2)C#N)C(F)(F)F)cc1
Show InChI InChI=1S/C22H16F3N3O4/c23-22(24,25)16-9-8-15(10-13(16)11-26)32-14-6-4-12(5-7-14)17-2-1-3-18(28-17)19(29)20(30)21(27)31/h1-10,19-20,29-30H,(H2,27,31)/t19-,20+/m1/s1
PDB

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US Patent
340n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM317563
PNG
((2S,3R)-Ethyl 3-(6-(4-(3-cyano-4-(trifluoromethyl)...)
Show SMILES CCOC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(c(c2)C#N)C(F)(F)F)cc1
Show InChI InChI=1S/C24H19F3N2O5/c1-2-33-23(32)22(31)21(30)20-5-3-4-19(29-20)14-6-8-16(9-7-14)34-17-10-11-18(24(25,26)27)15(12-17)13-28/h3-12,21-22,30-31H,2H2,1H3/t21-,22+/m1/s1
PDB

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917n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190561
PNG
(US9181185, 19 | US9624194, Compound 19)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1cccc(n1)-c1ccc(Oc2ccc(c(c2)C#N)C(F)(F)F)cc1
Show InChI InChI=1S/C22H16F3N3O4/c23-22(24,25)16-9-8-15(10-13(16)11-26)32-14-6-4-12(5-7-14)17-2-1-3-18(28-17)19(29)20(30)21(27)31/h1-10,19-20,29-30H,(H2,27,31)/t19-,20+/m0/s1
PDB

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2.26E+3n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190541
PNG
(US9181185, 30b | US9624194, Compound 30b)
Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C21H17F3N2O4/c22-21(23,24)13-6-10-15(11-7-13)30-14-8-4-12(5-9-14)16-2-1-3-17(26-16)18(27)19(28)20(25)29/h1-11,18-19,27-28H,(H2,25,29)/t18-,19+/m1/s1
PDB

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n/an/a 130n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM317560
PNG
((2S,3R)-Ethyl 2,3-dihydroxy-3-(1-(4-((5-(trifluoro...)
Show SMILES CCOC(=O)[C@@H](O)[C@H](O)c1cn(-c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2)c2ccccc12
Show InChI InChI=1S/C25H21F3N2O5/c1-2-34-24(33)23(32)22(31)19-14-30(20-6-4-3-5-18(19)20)16-8-10-17(11-9-16)35-21-12-7-15(13-29-21)25(26,27)28/h3-14,22-23,31-32H,2H2,1H3/t22-,23+/m1/s1
PDB

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US Patent
n/an/a 152n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190558
PNG
(US9181185, 8 | US9624194, Compound 8)
Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cn(-c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2)c2ccccc12
Show InChI InChI=1S/C23H18F3N3O4/c24-23(25,26)13-5-10-19(28-11-13)33-15-8-6-14(7-9-15)29-12-17(20(30)21(31)22(27)32)16-3-1-2-4-18(16)29/h1-12,20-21,30-31H,(H2,27,32)/t20-,21+/m1/s1
PDB

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n/an/a 193n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190561
PNG
(US9181185, 19 | US9624194, Compound 19)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1cccc(n1)-c1ccc(Oc2ccc(c(c2)C#N)C(F)(F)F)cc1
Show InChI InChI=1S/C22H16F3N3O4/c23-22(24,25)16-9-8-15(10-13(16)11-26)32-14-6-4-12(5-7-14)17-2-1-3-18(28-17)19(29)20(30)21(27)31/h1-10,19-20,29-30H,(H2,27,31)/t19-,20+/m0/s1
PDB

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n/an/a 244n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM317563
PNG
((2S,3R)-Ethyl 3-(6-(4-(3-cyano-4-(trifluoromethyl)...)
Show SMILES CCOC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(c(c2)C#N)C(F)(F)F)cc1
Show InChI InChI=1S/C24H19F3N2O5/c1-2-33-23(32)22(31)21(30)20-5-3-4-19(29-20)14-6-8-16(9-7-14)34-17-10-11-18(24(25,26)27)15(12-17)13-28/h3-12,21-22,30-31H,2H2,1H3/t21-,22+/m1/s1
PDB

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n/an/a 246n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190553
PNG
(US9181185, 30g | US9624194, Compound 30g)
Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C21H17N3O4/c22-12-13-4-8-15(9-5-13)28-16-10-6-14(7-11-16)17-2-1-3-18(24-17)19(25)20(26)21(23)27/h1-11,19-20,25-26H,(H2,23,27)/t19-,20+/m1/s1
PDB

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n/an/a 262n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190557
PNG
(US9181185, 7 | US9624194, Compound 7)
Show SMILES CNC(=O)[C@@H](O)[C@H](O)c1cn(-c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2)c2ccccc12
Show InChI InChI=1S/C24H20F3N3O4/c1-28-23(33)22(32)21(31)18-13-30(19-5-3-2-4-17(18)19)15-7-9-16(10-8-15)34-20-11-6-14(12-29-20)24(25,26)27/h2-13,21-22,31-32H,1H3,(H,28,33)/t21-,22+/m1/s1
PDB

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n/an/a 282n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190560
PNG
(US9181185, 15 | US9624194, Compound 15)
Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(c(c2)C#N)C(F)(F)F)cc1
Show InChI InChI=1S/C22H16F3N3O4/c23-22(24,25)16-9-8-15(10-13(16)11-26)32-14-6-4-12(5-7-14)17-2-1-3-18(28-17)19(29)20(30)21(27)31/h1-10,19-20,29-30H,(H2,27,31)/t19-,20+/m1/s1
PDB

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n/an/a 304n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190555
PNG
(US9181185, 5 | US9624194, Compound 5)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1cn(-c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2)c2ccccc12
Show InChI InChI=1S/C23H18F3N3O4/c24-23(25,26)13-5-10-19(28-11-13)33-15-8-6-14(7-9-15)29-12-17(20(30)21(31)22(27)32)16-3-1-2-4-18(16)29/h1-12,20-21,30-31H,(H2,27,32)/t20-,21+/m0/s1
PDB

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n/an/a 314n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190551
PNG
(US9181185, 30f | US9624194, Compound 30f)
Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(Cl)nc2)cc1
Show InChI InChI=1S/C19H16ClN3O4/c20-16-9-8-13(10-22-16)27-12-6-4-11(5-7-12)14-2-1-3-15(23-14)17(24)18(25)19(21)26/h1-10,17-18,24-25H,(H2,21,26)/t17-,18+/m1/s1
PDB

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n/an/a 376n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190542
PNG
(US9181185, 31b | US9624194, Compound 31b)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1cccc(n1)-c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C21H17F3N2O4/c22-21(23,24)13-6-10-15(11-7-13)30-14-8-4-12(5-9-14)16-2-1-3-17(26-16)18(27)19(28)20(25)29/h1-11,18-19,27-28H,(H2,25,29)/t18-,19+/m0/s1
PDB

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n/an/a 383n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190549
PNG
(US9181185, 30e | US9624194, Compound 30e)
Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(C#N)c(c2)C(F)(F)F)cc1
Show InChI InChI=1S/C22H16F3N3O4/c23-22(24,25)16-10-15(9-6-13(16)11-26)32-14-7-4-12(5-8-14)17-2-1-3-18(28-17)19(29)20(30)21(27)31/h1-10,19-20,29-30H,(H2,27,31)/t19-,20+/m1/s1
PDB

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n/an/a 461n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190550
PNG
(US9181185, 31e | US9624194, Compound 31e)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1cccc(n1)-c1ccc(Oc2ccc(C#N)c(c2)C(F)(F)F)cc1
Show InChI InChI=1S/C22H16F3N3O4/c23-22(24,25)16-10-15(9-6-13(16)11-26)32-14-7-4-12(5-8-14)17-2-1-3-18(28-17)19(29)20(30)21(27)31/h1-10,19-20,29-30H,(H2,27,31)/t19-,20+/m0/s1
PDB

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n/an/a 489n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190562
PNG
(US9181185, 26 | US9624194, Compound 26)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1ccnc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C19H16FN3O4/c20-12-3-7-14(8-4-12)27-13-5-1-11(2-6-13)19-22-10-9-15(23-19)16(24)17(25)18(21)26/h1-10,16-17,24-25H,(H2,21,26)/t16-,17+/m0/s1
PDB

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n/an/a 625n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190554
PNG
(US9181185, 31g | US9624194, Compound 31g)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1cccc(n1)-c1ccc(Oc2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C21H17N3O4/c22-12-13-4-8-15(9-5-13)28-16-10-6-14(7-11-16)17-2-1-3-18(24-17)19(25)20(26)21(23)27/h1-11,19-20,25-26H,(H2,23,27)/t19-,20+/m0/s1
PDB

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n/an/a 690n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190545
PNG
(US9181185, 30c | US9624194, Compound 30c)
Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1
Show InChI InChI=1S/C20H16F3N3O4/c21-20(22,23)12-6-9-16(25-10-12)30-13-7-4-11(5-8-13)14-2-1-3-15(26-14)17(27)18(28)19(24)29/h1-10,17-18,27-28H,(H2,24,29)/t17-,18+/m1/s1
PDB

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US Patent
n/an/a 711n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190552
PNG
(US9181185, 31f | US9624194, Compound 31f)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1cccc(n1)-c1ccc(Oc2ccc(Cl)nc2)cc1
Show InChI InChI=1S/C19H16ClN3O4/c20-16-9-8-13(10-22-16)27-12-6-4-11(5-7-12)14-2-1-3-15(23-14)17(24)18(25)19(21)26/h1-10,17-18,24-25H,(H2,21,26)/t17-,18+/m0/s1
PDB

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n/an/a 804n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190547
PNG
(US9181185, 30d | US9624194, Compound 30d)
Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(Cl)cn2)cc1
Show InChI InChI=1S/C19H16ClN3O4/c20-12-6-9-16(22-10-12)27-13-7-4-11(5-8-13)14-2-1-3-15(23-14)17(24)18(25)19(21)26/h1-10,17-18,24-25H,(H2,21,26)/t17-,18+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

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US Patent
n/an/a 1.19E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190543
PNG
(US9181185, 30a | US9624194, Compound 30a)
Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H17FN2O4/c21-13-6-10-15(11-7-13)27-14-8-4-12(5-9-14)16-2-1-3-17(23-16)18(24)19(25)20(22)26/h1-11,18-19,24-25H,(H2,22,26)/t18-,19+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

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US Patent
n/an/a 1.41E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190548
PNG
(US9181185, 31d | US9624194, Compound 31d)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1cccc(n1)-c1ccc(Oc2ccc(Cl)cn2)cc1
Show InChI InChI=1S/C19H16ClN3O4/c20-12-6-9-16(22-10-12)27-13-7-4-11(5-8-13)14-2-1-3-15(23-14)17(24)18(25)19(21)26/h1-10,17-18,24-25H,(H2,21,26)/t17-,18+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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DrugBank
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UniChem

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US Patent
n/an/a 1.44E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190546
PNG
(US9181185, 31c | US9624194, Compound 31c)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1cccc(n1)-c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1
Show InChI InChI=1S/C20H16F3N3O4/c21-20(22,23)12-6-9-16(25-10-12)30-13-7-4-11(5-8-13)14-2-1-3-15(26-14)17(27)18(28)19(24)29/h1-10,17-18,27-28H,(H2,24,29)/t17-,18+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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PC cid
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US Patent
n/an/a 1.69E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM190544
PNG
(US9181185, 31a | US9624194, Compound 31a)
Show SMILES NC(=O)[C@H](O)[C@@H](O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H17FN2O4/c21-13-6-10-15(11-7-13)27-14-8-4-12(5-9-14)16-2-1-3-17(23-16)18(24)19(25)20(22)26/h1-11,18-19,24-25H,(H2,22,26)/t18-,19+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.85E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...


US Patent US9624194 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%