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Patent code US9624234

Compile Data Set for Download or QSAR
Found 25 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(HUMAN)
BDBM318438
PNG
((2S,4R)-4-((4,4-dimethylpent-2-yn-1-yl)(methyl)ami...)
Show SMILES CN(CC#CC(C)(C)C)[C@@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H34N2O3/c1-28(2,3)17-11-18-29(4)23-16-19-30(24(20-23)27(32)33)26(31)25(21-12-7-5-8-13-21)22-14-9-6-10-15-22/h5-10,12-15,23-25H,16,18-20H2,1-4H3,(H,32,33)/t23-,24+/m1/s1
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US Patent
n/an/a 33.9n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318435
PNG
(((2S,4R)-1-(2,2-diphenylacetyl)-4-((3-(4-fluorophe...)
Show SMILES CC(C#CCN(C)[C@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1)c1ccc(F)cc1
Show InChI InChI=1S/C32H33FN2O3/c1-23(24-15-17-27(33)18-16-24)10-9-20-34(2)28-19-21-35(29(22-28)32(37)38)31(36)30(25-11-5-3-6-12-25)26-13-7-4-8-14-26/h3-8,11-18,23,28-30H,19-22H2,1-2H3,(H,37,38)/t23?,28-,29-/m0/s1
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n/an/a 55.9n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318414
PNG
( (2S,4R)-4-benzyloxy-1-(2,2-diphenylacetyl)piperid...)
Show SMILES OC(=O)[C@@H]1C[C@@H](CCN1C(=O)C(c1ccccc1)c1ccccc1)OCc1ccccc1
Show InChI InChI=1S/C27H27NO4/c29-26(25(21-12-6-2-7-13-21)22-14-8-3-9-15-22)28-17-16-23(18-24(28)27(30)31)32-19-20-10-4-1-5-11-20/h1-15,23-25H,16-19H2,(H,30,31)/t23-,24+/m1/s1
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n/an/a 76.7n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318430
PNG
((2S,4R)-1-(2,2-diphenylacetyl)-4-((3-phenylpropyl)...)
Show SMILES OC(=O)[C@@H]1C[C@@H](CCN1C(=O)C(c1ccccc1)c1ccccc1)OCCCc1ccccc1
Show InChI InChI=1S/C29H31NO4/c31-28(27(23-14-6-2-7-15-23)24-16-8-3-9-17-24)30-19-18-25(21-26(30)29(32)33)34-20-10-13-22-11-4-1-5-12-22/h1-9,11-12,14-17,25-27H,10,13,18-21H2,(H,32,33)/t25-,26+/m1/s1
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n/an/a 101n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318426
PNG
((2S,4S)-1-(2,2-diphenylacetyl)-4-(methyl(3-pheneth...)
Show SMILES COC(=O)[C@@H]1C[C@@H](CCN1C(=O)C(c1ccccc1)c1ccccc1)N(C)CCCc1ccccc1
Show InChI InChI=1S/C31H36N2O3/c1-32(21-12-15-24-13-6-3-7-14-24)27-20-22-33(28(23-27)31(35)36-2)30(34)29(25-16-8-4-9-17-25)26-18-10-5-11-19-26/h3-11,13-14,16-19,27-29H,12,15,20-23H2,1-2H3/t27-,28+/m1/s1
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NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318423
PNG
((2S,4R)-4-(2,2-diphenylacetyl)-4-(methyl(3-phenylp...)
Show SMILES CN(CC#Cc1ccccc1)[C@@]1(CCN[C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H30N2O3/c1-32(21-11-14-23-12-5-2-6-13-23)30(19-20-31-26(22-30)29(34)35)28(33)27(24-15-7-3-8-16-24)25-17-9-4-10-18-25/h2-10,12-13,15-18,26-27,31H,19-22H2,1H3,(H,34,35)/t26-,30+/m0/s1
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n/an/a 108n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318440
PNG
( (2′S,3R,4′R)-1-(2,2-diphenylacetyl)-3...)
Show SMILES OC(=O)[C@H]1C[C@@H](CCN1C(=O)C(c1ccccc1)c1ccccc1)N1CCC[C@H](C1)c1ccccc1
Show InChI InChI=1S/C31H34N2O3/c34-30(29(24-13-6-2-7-14-24)25-15-8-3-9-16-25)33-20-18-27(21-28(33)31(35)36)32-19-10-17-26(22-32)23-11-4-1-5-12-23/h1-9,11-16,26-29H,10,17-22H2,(H,35,36)/t26-,27-,28-/m1/s1
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n/an/a 111n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318433
PNG
((2S,4R)-1-(2,2-diphenylacetyl)-4-((methyl(4-methyl...)
Show SMILES CC(C)C#CCN(C)[C@@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H32N2O3/c1-20(2)11-10-17-28(3)23-16-18-29(24(19-23)27(31)32)26(30)25(21-12-6-4-7-13-21)22-14-8-5-9-15-22/h4-9,12-15,20,23-25H,16-19H2,1-3H3,(H,31,32)/t23-,24+/m1/s1
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n/an/a 153n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318049
PNG
( (S)-3-(2,2-diphenylacetyl)-1,2,3,4-tetrahydrobenz...)
Show SMILES OC(=O)[C@@H]1Cc2c(CN1C(=O)C(c1ccccc1)c1ccccc1)ccc1Oc3ccccc3Oc21
Show InChI InChI=1S/C30H23NO5/c32-29(27(19-9-3-1-4-10-19)20-11-5-2-6-12-20)31-18-21-15-16-26-28(22(21)17-23(31)30(33)34)36-25-14-8-7-13-24(25)35-26/h1-16,23,27H,17-18H2,(H,33,34)/t23-/m0/s1
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n/an/a 159n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318442
PNG
( (2′S,3S,4′S)-1′-(2,2-diphenylac...)
Show SMILES OC(=O)[C@@H]1C[C@H](CCN1C(=O)C(c1ccccc1)c1ccccc1)N1CCC[C@H](C1)c1ccccc1
Show InChI InChI=1S/C31H34N2O3/c34-30(29(24-13-6-2-7-14-24)25-15-8-3-9-16-25)33-20-18-27(21-28(33)31(35)36)32-19-10-17-26(22-32)23-11-4-1-5-12-23/h1-9,11-16,26-29H,10,17-22H2,(H,35,36)/t26-,27+,28+/m1/s1
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n/an/a 170n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318046
PNG
( (S)-5-benzyl-2-(2,2-diphenylacetyl)-2,3,4,5-tetra...)
Show SMILES OC(=O)[C@@H]1CC2=C3C(Cc4ccccc4)C=CC=C3N=C2CN1C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C33H28N2O3/c36-32(30(23-13-6-2-7-14-23)24-15-8-3-9-16-24)35-21-28-26(20-29(35)33(37)38)31-25(17-10-18-27(31)34-28)19-22-11-4-1-5-12-22/h1-18,25,29-30H,19-21H2,(H,37,38)/t25?,29-/m0/s1
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NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318050
PNG
((2S)-4-(benzyloxy)-1-(2,2-diphenylacetyl)piperidin...)
Show SMILES OC(=O)[C@@H]1CC(CCN1C(=O)C(c1ccccc1)c1ccccc1)OCc1ccccc1
Show InChI InChI=1S/C27H27NO4/c29-26(25(21-12-6-2-7-13-21)22-14-8-3-9-15-22)28-17-16-23(18-24(28)27(30)31)32-19-20-10-4-1-5-11-20/h1-15,23-25H,16-19H2,(H,30,31)/t23?,24-/m0/s1
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NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318437
PNG
((2S,4R)-1-(2,2-diphenylacetyl)-4-((3-(4-fluorophen...)
Show SMILES OC(=O)[C@@H]1C[C@@H](CCN1C(=O)C(c1ccccc1)c1ccccc1)OCC#Cc1ccc(F)cc1
Show InChI InChI=1S/C29H26FNO4/c30-24-15-13-21(14-16-24)8-7-19-35-25-17-18-31(26(20-25)29(33)34)28(32)27(22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-6,9-16,25-27H,17-20H2,(H,33,34)/t25-,26+/m1/s1
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NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318429
PNG
((2S,4R)-1-(2,2-diphenylacetyl)-4-((3-phenylprop-2-...)
Show SMILES OC(=O)[C@@H]1C[C@@H](CCN1C(=O)C(c1ccccc1)c1ccccc1)OCC#Cc1ccccc1
Show InChI InChI=1S/C29H27NO4/c31-28(27(23-14-6-2-7-15-23)24-16-8-3-9-17-24)30-19-18-25(21-26(30)29(32)33)34-20-10-13-22-11-4-1-5-12-22/h1-9,11-12,14-17,25-27H,18-21H2,(H,32,33)/t25-,26+/m1/s1
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NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318439
PNG
((2′S,3R,4′R)-1′-(2,2-diphenylace...)
Show SMILES OC(=O)[C@@H]1C[C@@H](CCN1C(=O)C(c1ccccc1)c1ccccc1)N1CCC[C@@H](C1)c1ccccc1
Show InChI InChI=1S/C31H34N2O3/c34-30(29(24-13-6-2-7-14-24)25-15-8-3-9-16-25)33-20-18-27(21-28(33)31(35)36)32-19-10-17-26(22-32)23-11-4-1-5-12-23/h1-9,11-16,26-29H,10,17-22H2,(H,35,36)/t26-,27+,28-/m0/s1
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NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318434
PNG
((2S,4S)-1-(2,2-diphenylacetyl)-4-((methyl(4-methyl...)
Show SMILES CC(C)C#CCN(C)[C@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H32N2O3/c1-20(2)11-10-17-28(3)23-16-18-29(24(19-23)27(31)32)26(30)25(21-12-6-4-7-13-21)22-14-8-5-9-15-22/h4-9,12-15,20,23-25H,16-19H2,1-3H3,(H,31,32)/t23-,24-/m0/s1
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NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318428
PNG
( (2S,4S)-4-(benzyl(methyl)amino)-1-(2,2-diphenylac...)
Show SMILES CN(Cc1ccccc1)[C@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H30N2O3/c1-29(20-21-11-5-2-6-12-21)24-17-18-30(25(19-24)28(32)33)27(31)26(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,24-26H,17-20H2,1H3,(H,32,33)/t24-,25-/m0/s1
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NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318431
PNG
((2S,4R)-4-((but-2-yn-1-yl)methyl)amino)-1-(2,2-dip...)
Show SMILES CC#CCCN[C@@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H28N2O3/c1-2-3-10-16-26-21-15-17-27(22(18-21)25(29)30)24(28)23(19-11-6-4-7-12-19)20-13-8-5-9-14-20/h4-9,11-14,21-23,26H,10,15-18H2,1H3,(H,29,30)/t21-,22+/m1/s1
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n/an/a 852n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318427
PNG
((2S,4R)-4-(benzyl(methyl)amino)-1-(2,2-diphenylace...)
Show SMILES CN(Cc1ccccc1)[C@@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H30N2O3/c1-29(20-21-11-5-2-6-12-21)24-17-18-30(25(19-24)28(32)33)27(31)26(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,24-26H,17-20H2,1H3,(H,32,33)/t24-,25+/m1/s1
PDB

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n/an/a 854n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318422
PNG
( (2S,4R)-1-(2,2-diphenylacetyl)-4-(methyl(phenylpr...)
Show SMILES CN(CCCc1ccccc1)[C@@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H34N2O3/c1-31(20-11-14-23-12-5-2-6-13-23)26-19-21-32(27(22-26)30(34)35)29(33)28(24-15-7-3-8-16-24)25-17-9-4-10-18-25/h2-10,12-13,15-18,26-28H,11,14,19-22H2,1H3,(H,34,35)/t26-,27+/m1/s1
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n/an/a 918n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318436
PNG
((2S,4S)-1-(2,2-diphenylacetyl)-4-((3-(4-fluorophen...)
Show SMILES CN(CC#Cc1ccc(F)cc1)[C@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H29FN2O3/c1-32(19-8-9-22-14-16-25(31)17-15-22)26-18-20-33(27(21-26)30(35)36)29(34)28(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-7,10-17,26-28H,18-21H2,1H3,(H,35,36)/t26-,27-/m0/s1
PDB

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PC sid
UniChem
US Patent
n/an/a 1.04E+3n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318441
PNG
((2′S,3S,4′R)-1′-(2,2-diphenylace...)
Show SMILES OC(=O)[C@@H]1C[C@@H](CCN1C(=O)C(c1ccccc1)c1ccccc1)N1CCC[C@H](C1)c1ccccc1
Show InChI InChI=1S/C31H34N2O3/c34-30(29(24-13-6-2-7-14-24)25-15-8-3-9-16-25)33-20-18-27(21-28(33)31(35)36)32-19-10-17-26(22-32)23-11-4-1-5-12-23/h1-9,11-16,26-29H,10,17-22H2,(H,35,36)/t26-,27-,28+/m1/s1
PDB

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UniChem
US Patent
n/an/a 1.44E+3n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318432
PNG
((2S,4S)-4-((but-2-yn-1-yl)methyl)amino)-1-(2,2-dip...)
Show SMILES CC#CCCN[C@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H28N2O3/c1-2-3-10-16-26-21-15-17-27(22(18-21)25(29)30)24(28)23(19-11-6-4-7-12-19)20-13-8-5-9-14-20/h4-9,11-14,21-23,26H,10,15-18H2,1H3,(H,29,30)/t21-,22-/m0/s1
PDB

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UniChem
US Patent
n/an/a 2.05E+3n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318424
PNG
((2S,4S)-1-(2,2-diphenylacetyl)-4-(methyl(3-phenylp...)
Show SMILES CN(CC#Cc1ccccc1)[C@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H30N2O3/c1-31(20-11-14-23-12-5-2-6-13-23)26-19-21-32(27(22-26)30(34)35)29(33)28(24-15-7-3-8-16-24)25-17-9-4-10-18-25/h2-10,12-13,15-18,26-28H,19-22H2,1H3,(H,34,35)/t26-,27-/m0/s1
PDB

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UniChem
US Patent
n/an/a 2.71E+3n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
Angiotensin II receptor


(HUMAN)
BDBM318422
PNG
( (2S,4R)-1-(2,2-diphenylacetyl)-4-(methyl(phenylpr...)
Show SMILES CN(CCCc1ccccc1)[C@@H]1CCN([C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H34N2O3/c1-31(20-11-14-23-12-5-2-6-13-23)26-19-21-32(27(22-26)30(34)35)29(33)28(24-15-7-3-8-16-24)25-17-9-4-10-18-25/h2-10,12-13,15-18,26-28H,11,14,19-22H2,1H3,(H,34,35)/t26-,27+/m1/s1
PDB

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UniChem
US Patent
n/an/a 5.09E+3n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...


US Patent US9624234 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%