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Found 15 Enz. Inhib. hit(s) with all data for entry = 1473
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155300(US9006246, 31(24) | US9636330, 31(24))
Affinity DataIC50:  5nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155280(US9006246, 12(97) | US9636330, 12(97))
Affinity DataIC50:  6.70nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155341(US9006246, 51(48) | US9636330, 51(48))
Affinity DataIC50:  7.80nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155279(US9006246, 12(42) | US9636330, 12(42))
Affinity DataIC50:  9.60nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155306(US9006246, 31(140) | US9636330, 31(140))
Affinity DataIC50:  11nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155303(US9006246, 31(127) | US9636330, 31(127))
Affinity DataIC50:  11nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155310(US9006246, 31(169) | US9636330, 31(169))
Affinity DataIC50:  13nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155271(US9006246, 9 | US9636330, 9(2))
Affinity DataIC50:  16nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM325570(US9636330, 48(9) | trans-4-{2-[9-(4-chlorobenzyl)-...)
Affinity DataIC50:  25nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM325569( trans-4-{2-[9-(4-fluorobenzyl)-5,6,8,9-tetrahydro...)
Affinity DataIC50:  26nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155263(US9006246, 3 | US9636330, 3)
Affinity DataIC50:  34nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155321(US9006246, 35(122) | US9636330, 35(122))
Affinity DataIC50:  35nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM325562(3-({2-[9-(3-fluorobenzyl)-5,6,8,9-tetrahydro-7H-py...)
Affinity DataIC50:  83nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM325558(6-[9-(3-fluorobenzyl)-5,6,8,9-tetrahydro-7H-pyrido...)
Affinity DataIC50:  91nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155320(US9006246, 35(2) | US9636330, 35(2))
Affinity DataIC50:  110nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent