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Patent code US9662310

Compile Data Set for Download or QSAR
Found 68 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
tafia


(Homo sapiens (Human))
BDBM326336
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(3,3-dimethylbuty...)
Show SMILES CC(C)(C)CCn1cnc(c1)[C@]1(C[C@@H]1CCCN)C(O)=O
Show InChI InChI=1S/C16H27N3O2/c1-15(2,3)6-8-19-10-13(18-11-19)16(14(20)21)9-12(16)5-4-7-17/h10-12H,4-9,17H2,1-3H3,(H,20,21)/t12-,16+/m0/s1
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n/an/a 4.5n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326397
PNG
((1R,2S)-2-[(2R)-2-(Aminomethyl)butyl]-1-(1-phenyl-...)
Show SMILES CC[C@@H](CNC(=O)OC(C)(C)C)C[C@H]1C[C@]1(C(=O)OC)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C24H33N3O4/c1-6-17(14-25-22(29)31-23(2,3)4)12-18-13-24(18,21(28)30-5)20-15-27(16-26-20)19-10-8-7-9-11-19/h7-11,15-18H,6,12-14H2,1-5H3,(H,25,29)/t17-,18+,24-/m1/s1
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n/an/a 7.90n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326395
PNG
((1R,2S)-2-[(2R)-2-(Aminomethyl)butyl]-1-(1-pyridin...)
Show SMILES CC[C@@H](CN)CC1C[C@]1(C(O)=O)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C17H22N4O2/c1-2-12(9-18)7-13-8-17(13,16(22)23)14-10-21(11-20-14)15-5-3-4-6-19-15/h3-6,10-13H,2,7-9,18H2,1H3,(H,22,23)/t12-,13?,17-/m1/s1
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n/an/a 8.30n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326393
PNG
((1R,2S)-2-[(2R)-3-Amino-2-methylpropyl]-1-[1-(5-me...)
Show SMILES C[C@@H](CN)C[C@H]1C[C@]1(C(O)=O)c1cn(cn1)-c1ccc(C)cn1
Show InChI InChI=1S/C17H22N4O2/c1-11-3-4-15(19-8-11)21-9-14(20-10-21)17(16(22)23)6-13(17)5-12(2)7-18/h3-4,8-10,12-13H,5-7,18H2,1-2H3,(H,22,23)/t12-,13+,17-/m1/s1
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DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326336
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(3,3-dimethylbuty...)
Show SMILES CC(C)(C)CCn1cnc(c1)[C@]1(C[C@@H]1CCCN)C(O)=O
Show InChI InChI=1S/C16H27N3O2/c1-15(2,3)6-8-19-10-13(18-11-19)16(14(20)21)9-12(16)5-4-7-17/h10-12H,4-9,17H2,1-3H3,(H,20,21)/t12-,16+/m0/s1
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n/an/a 8.70n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326389
PNG
((1R,2S)-2-[(2R)-3-Amino-2-methylpropyl]-1-(1-pyrid...)
Show SMILES C[C@@H](CN)CC1C[C@]1(C(O)=O)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C16H20N4O2/c1-11(8-17)6-12-7-16(12,15(21)22)13-9-20(10-19-13)14-4-2-3-5-18-14/h2-5,9-12H,6-8,17H2,1H3,(H,21,22)/t11-,12?,16-/m1/s1
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n/an/a 11n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326383
PNG
((1R,2S)-2-(3-Aminopropyl)-1-(1-pyridin-2-yl-1H-imi...)
Show SMILES NCCC[C@H]1C[C@]1(C(O)=O)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C15H18N4O2/c16-6-3-4-11-8-15(11,14(20)21)12-9-19(10-18-12)13-5-1-2-7-17-13/h1-2,5,7,9-11H,3-4,6,8,16H2,(H,20,21)/t11-,15+/m0/s1
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n/an/a 11n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326398
PNG
((1R,2S)-2-[ | US9662310, Example 63)
Show SMILES CC[C@H](CN)C[C@H]1C[C@]1(C(O)=O)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C18H23N3O2/c1-2-13(10-19)8-14-9-18(14,17(22)23)16-11-21(12-20-16)15-6-4-3-5-7-15/h3-7,11-14H,2,8-10,19H2,1H3,(H,22,23)/t13-,14-,18+/m0/s1
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n/an/a 12n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326403
PNG
(2-[(2R)-4-Aminobutane-2-yl]-1-[1-(pyridin-2-yl)-1H...)
Show SMILES C[C@H](CCN)C1CC1(C(O)=O)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C16H20N4O2/c1-11(5-6-17)12-8-16(12,15(21)22)13-9-20(10-19-13)14-4-2-3-7-18-14/h2-4,7,9-12H,5-6,8,17H2,1H3,(H,21,22)/t11-,12?,16?/m1/s1
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n/an/a 12n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326365
PNG
((1R,2S)-2-(3-Aminopropyl)-1-(1-phenyl-1H-imidazol-...)
Show SMILES NCCC[C@H]1C[C@]1(C(O)=O)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C16H19N3O2/c17-8-4-5-12-9-16(12,15(20)21)14-10-19(11-18-14)13-6-2-1-3-7-13/h1-3,6-7,10-12H,4-5,8-9,17H2,(H,20,21)/t12-,16+/m0/s1
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n/an/a 13n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326388
PNG
((1R,2S)-2-[(2-Aminomethyl)butyl]-1-(1-phenyl-1H-im...)
Show SMILES CCC(CN)CC1C[C@]1(C(O)=O)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C18H23N3O2/c1-2-13(10-19)8-14-9-18(14,17(22)23)16-11-21(12-20-16)15-6-4-3-5-7-15/h3-7,11-14H,2,8-10,19H2,1H3,(H,22,23)/t13?,14?,18-/m1/s1
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n/an/a 13n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326385
PNG
((1R,2S)-2-[(2R)-3-Amino-2-methylpropyl]-1-(1-pheny...)
Show SMILES COC(=O)[C@@]1(C[C@@H]1C[C@@H](C)CNC(=O)OC(C)(C)C)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C23H31N3O4/c1-16(13-24-21(28)30-22(2,3)4)11-17-12-23(17,20(27)29-5)19-14-26(15-25-19)18-9-7-6-8-10-18/h6-10,14-17H,11-13H2,1-5H3,(H,24,28)/t16-,17+,23-/m1/s1
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n/an/a 14n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326340
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(trans-4-methylcy...)
Show SMILES C[C@H]1CC[C@@H](CC1)n1cnc(c1)C1(CC1CCCN)C(O)=O
Show InChI InChI=1S/C17H27N3O2/c1-12-4-6-14(7-5-12)20-10-15(19-11-20)17(16(21)22)9-13(17)3-2-8-18/h10-14H,2-9,18H2,1H3,(H,21,22)/t12-,13?,14-,17?
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n/an/a 14n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326365
PNG
((1R,2S)-2-(3-Aminopropyl)-1-(1-phenyl-1H-imidazol-...)
Show SMILES NCCC[C@H]1C[C@]1(C(O)=O)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C16H19N3O2/c17-8-4-5-12-9-16(12,15(20)21)14-10-19(11-18-14)13-6-2-1-3-7-13/h1-3,6-7,10-12H,4-5,8-9,17H2,(H,20,21)/t12-,16+/m0/s1
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n/an/a 15n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326381
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-(1-isoquinolin-3-yl-...)
Show SMILES CC(C)(C)OC(=O)NCCCC1CC1(C#N)c1cn(cn1)-c1cc2ccccc2cn1
Show InChI InChI=1S/C24H27N5O2/c1-23(2,3)31-22(30)26-10-6-9-19-12-24(19,15-25)20-14-29(16-28-20)21-11-17-7-4-5-8-18(17)13-27-21/h4-5,7-8,11,13-14,16,19H,6,9-10,12H2,1-3H3,(H,26,30)
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n/an/a 16n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326379
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(5-methoxypyridin...)
Show SMILES COc1ccc(nc1)-n1cnc(c1)C1(CC1CCCNC(=O)OC(C)(C)C)C#N
Show InChI InChI=1S/C21H27N5O3/c1-20(2,3)29-19(27)23-9-5-6-15-10-21(15,13-22)17-12-26(14-25-17)18-8-7-16(28-4)11-24-18/h7-8,11-12,14-15H,5-6,9-10H2,1-4H3,(H,23,27)
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n/an/a 16n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326342
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(4-methylphenyl)-...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(C)cc1
Show InChI InChI=1S/C28H39N3O6/c1-19-11-13-21(14-12-19)30-17-22(29-18-30)28(23(32)35-8)16-20(28)10-9-15-31(24(33)36-26(2,3)4)25(34)37-27(5,6)7/h11-14,17-18,20H,9-10,15-16H2,1-8H3
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n/an/a 16n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326384
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(5-methylpyridin-...)
Show SMILES Cc1ccc(nc1)-n1cnc(c1)C1(CC1CCCN)C(O)=O
Show InChI InChI=1S/C16H20N4O2/c1-11-4-5-14(18-8-11)20-9-13(19-10-20)16(15(21)22)7-12(16)3-2-6-17/h4-5,8-10,12H,2-3,6-7,17H2,1H3,(H,21,22)
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n/an/a 18n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326399
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(4-methylpyridin-...)
Show SMILES Cc1ccnc(c1)-n1cnc(c1)C1(CC1CCCN)C(O)=O
Show InChI InChI=1S/C16H20N4O2/c1-11-4-6-18-14(7-11)20-9-13(19-10-20)16(15(21)22)8-12(16)3-2-5-17/h4,6-7,9-10,12H,2-3,5,8,17H2,1H3,(H,21,22)
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n/an/a 19n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326376
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(5-fluoropyridin-...)
Show SMILES CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(F)cn1
Show InChI InChI=1S/C27H37FN4O6/c1-8-36-22(33)27(20-16-31(17-30-20)21-12-11-19(28)15-29-21)14-18(27)10-9-13-32(23(34)37-25(2,3)4)24(35)38-26(5,6)7/h11-12,15-18H,8-10,13-14H2,1-7H3
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n/an/a 19n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326350
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(4-fluorophenyl)-...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(F)cc1
Show InChI InChI=1S/C27H36FN3O6/c1-25(2,3)36-23(33)31(24(34)37-26(4,5)6)14-8-9-18-15-27(18,22(32)35-7)21-16-30(17-29-21)20-12-10-19(28)11-13-20/h10-13,16-18H,8-9,14-15H2,1-7H3
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n/an/a 21n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326353
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(4-chlorophenyl)-...)
Show SMILES CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H38ClN3O6/c1-8-36-23(33)28(22-17-31(18-30-22)21-13-11-20(29)12-14-21)16-19(28)10-9-15-32(24(34)37-26(2,3)4)25(35)38-27(5,6)7/h11-14,17-19H,8-10,15-16H2,1-7H3
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n/an/a 25n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326378
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(1-benzofuran-5-y...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc2occc2c1
Show InChI InChI=1S/C29H37N3O7/c1-27(2,3)38-25(34)32(26(35)39-28(4,5)6)13-8-9-20-16-29(20,24(33)36-7)23-17-31(18-30-23)21-10-11-22-19(15-21)12-14-37-22/h10-12,14-15,17-18,20H,8-9,13,16H2,1-7H3
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n/an/a 26n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326341
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-(1-phenyl-1H-imidazo...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C27H37N3O6/c1-25(2,3)35-23(32)30(24(33)36-26(4,5)6)15-11-12-19-16-27(19,22(31)34-7)21-17-29(18-28-21)20-13-9-8-10-14-20/h8-10,13-14,17-19H,11-12,15-16H2,1-7H3
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n/an/a 27n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326356
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(2-naphthyl)-1H-i...)
Show SMILES CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc2ccccc2c1
Show InChI InChI=1S/C32H41N3O6/c1-8-39-27(36)32(26-20-34(21-33-26)25-16-15-22-12-9-10-13-23(22)18-25)19-24(32)14-11-17-35(28(37)40-30(2,3)4)29(38)41-31(5,6)7/h9-10,12-13,15-16,18,20-21,24H,8,11,14,17,19H2,1-7H3
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n/an/a 27n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326375
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(4-cyanophenyl)-1...)
Show SMILES CC(C)(C)OC(=O)N(CCCC1CC1(C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(cc1)[N+]#[C-])C(=O)OC(C)(C)C
Show InChI InChI=1S/C31H42N4O6/c1-28(2,3)39-25(36)31(24-19-34(20-33-24)23-15-13-22(32-10)14-16-23)18-21(31)12-11-17-35(26(37)40-29(4,5)6)27(38)41-30(7,8)9/h13-16,19-21H,11-12,17-18H2,1-9H3
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n/an/a 29n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326339
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-(1-cyclohexyl-1H-imi...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)C1CCCCC1
Show InChI InChI=1S/C27H43N3O6/c1-25(2,3)35-23(32)30(24(33)36-26(4,5)6)15-11-12-19-16-27(19,22(31)34-7)21-17-29(18-28-21)20-13-9-8-10-14-20/h17-20H,8-16H2,1-7H3
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n/an/a 29n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326360
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-(1-pyridin-2-yl-1H-i...)
Show SMILES CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C27H38N4O6/c1-8-35-22(32)27(20-17-30(18-29-20)21-13-9-10-14-28-21)16-19(27)12-11-15-31(23(33)36-25(2,3)4)24(34)37-26(5,6)7/h9-10,13-14,17-19H,8,11-12,15-16H2,1-7H3
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n/an/a 29n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326374
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-(1-pyrimidin-2-yl-1H...)
Show SMILES CC(C)(C)OC(=O)N(CCCC1CC1(C(=O)OC(C)(C)C)c1cn(cn1)-c1ncccn1)C(=O)OC(C)(C)C
Show InChI InChI=1S/C28H41N5O6/c1-25(2,3)37-21(34)28(20-17-32(18-31-20)22-29-13-11-14-30-22)16-19(28)12-10-15-33(23(35)38-26(4,5)6)24(36)39-27(7,8)9/h11,13-14,17-19H,10,12,15-16H2,1-9H3
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n/an/a 30n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326346
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(4-ethylphenyl)-1...)
Show SMILES CCc1ccc(cc1)-n1cnc(c1)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC
Show InChI InChI=1S/C29H41N3O6/c1-9-20-12-14-22(15-13-20)31-18-23(30-19-31)29(24(33)36-8)17-21(29)11-10-16-32(25(34)37-27(2,3)4)26(35)38-28(5,6)7/h12-15,18-19,21H,9-11,16-17H2,1-8H3
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n/an/a 31n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326391
PNG
((1R,2S)-2-[(2S)-3-Amino-2-methylpropyl]-1-(1-pyrid...)
Show SMILES C[C@H](CN)CC1C[C@]1(C(O)=O)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C16H20N4O2/c1-11(8-17)6-12-7-16(12,15(21)22)13-9-20(10-19-13)14-4-2-3-5-18-14/h2-5,9-12H,6-8,17H2,1H3,(H,21,22)/t11-,12?,16+/m0/s1
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n/an/a 33n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326367
PNG
((1R*,2S*)-2-(3-Amino-2-methylpropyl)-1-(1-phenyl-1...)
Show SMILES COC(=O)C1(CC1CC(C)CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C28H39N3O6/c1-19(16-31(24(33)36-26(2,3)4)25(34)37-27(5,6)7)14-20-15-28(20,23(32)35-8)22-17-30(18-29-22)21-12-10-9-11-13-21/h9-13,17-20H,14-16H2,1-8H3
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n/an/a 35n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326386
PNG
((1R,2S)-2-[(2S)-3-Amino-2-methylpropyl]-1-(1-pheny...)
Show SMILES C[C@H](CN)C[C@H]1C[C@]1(C(O)=O)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C17H21N3O2/c1-12(9-18)7-13-8-17(13,16(21)22)15-10-20(11-19-15)14-5-3-2-4-6-14/h2-6,10-13H,7-9,18H2,1H3,(H,21,22)/t12-,13-,17+/m0/s1
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n/an/a 35n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326371
PNG
((1R*,2R*)-2-(3-Amino-1-methylpropyl)-1-(1-phenyl-1...)
Show SMILES CC(CCN)C1CC1(C(O)=O)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C17H21N3O2/c1-12(7-8-18)14-9-17(14,16(21)22)15-10-20(11-19-15)13-5-3-2-4-6-13/h2-6,10-12,14H,7-9,18H2,1H3,(H,21,22)
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n/an/a 36n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326347
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(4-methoxyphenyl)...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(OC)cc1
Show InChI InChI=1S/C28H39N3O7/c1-26(2,3)37-24(33)31(25(34)38-27(4,5)6)15-9-10-19-16-28(19,23(32)36-8)22-17-30(18-29-22)20-11-13-21(35-7)14-12-20/h11-14,17-19H,9-10,15-16H2,1-8H3
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n/an/a 36n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326343
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(3-methylphenyl)-...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1cccc(C)c1
Show InChI InChI=1S/C28H39N3O6/c1-19-11-9-13-21(15-19)30-17-22(29-18-30)28(23(32)35-8)16-20(28)12-10-14-31(24(33)36-26(2,3)4)25(34)37-27(5,6)7/h9,11,13,15,17-18,20H,10,12,14,16H2,1-8H3
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n/an/a 37n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326368
PNG
((1R*,2S*)-2-(3-Amino-2-methylpropyl)-1-[1-(4-methy...)
Show SMILES COC(=O)C1(CC1CC(C)CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(C)cc1
Show InChI InChI=1S/C29H41N3O6/c1-19-10-12-22(13-11-19)31-17-23(30-18-31)29(24(33)36-9)15-21(29)14-20(2)16-32(25(34)37-27(3,4)5)26(35)38-28(6,7)8/h10-13,17-18,20-21H,14-16H2,1-9H3
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n/an/a 39n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326357
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(3-fluorophenyl)-...)
Show SMILES CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1cccc(F)c1
Show InChI InChI=1S/C28H38FN3O6/c1-8-36-23(33)28(22-17-31(18-30-22)21-13-9-12-20(29)15-21)16-19(28)11-10-14-32(24(34)37-26(2,3)4)25(35)38-27(5,6)7/h9,12-13,15,17-19H,8,10-11,14,16H2,1-7H3
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n/an/a 40n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326401
PNG
((1R,2S)-2-[(2R)-2-(Aminomethyl)pentyl]-1-(1-pyridi...)
Show SMILES CCC[C@@H](CN)C[C@H]1C[C@]1(C(O)=O)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C18H24N4O2/c1-2-5-13(10-19)8-14-9-18(14,17(23)24)15-11-22(12-21-15)16-6-3-4-7-20-16/h3-4,6-7,11-14H,2,5,8-10,19H2,1H3,(H,23,24)/t13-,14+,18-/m1/s1
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n/an/a 41n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326345
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(3,4-dimethylphen...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(C)c(C)c1
Show InChI InChI=1S/C29H41N3O6/c1-19-12-13-22(15-20(19)2)31-17-23(30-18-31)29(24(33)36-9)16-21(29)11-10-14-32(25(34)37-27(3,4)5)26(35)38-28(6,7)8/h12-13,15,17-18,21H,10-11,14,16H2,1-9H3
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n/an/a 42n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326351
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(4-phenoxyphenyl)...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C33H41N3O7/c1-31(2,3)42-29(38)36(30(39)43-32(4,5)6)19-11-12-23-20-33(23,28(37)40-7)27-21-35(22-34-27)24-15-17-26(18-16-24)41-25-13-9-8-10-14-25/h8-10,13-18,21-23H,11-12,19-20H2,1-7H3
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n/an/a 52n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326382
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(1-naphthyl)-1H-i...)
Show SMILES NCCCC1CC1(C(O)=O)c1cn(cn1)-c1cccc2ccccc12
Show InChI InChI=1S/C20H21N3O2/c21-10-4-7-15-11-20(15,19(24)25)18-12-23(13-22-18)17-9-3-6-14-5-1-2-8-16(14)17/h1-3,5-6,8-9,12-13,15H,4,7,10-11,21H2,(H,24,25)
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n/an/a 54n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326377
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-(1-quinolin-2-yl-1H-...)
Show SMILES CC(C)(C)OC(=O)N(CCCC1CC1(C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc2ccccc2n1)C(=O)OC(C)(C)C
Show InChI InChI=1S/C33H44N4O6/c1-30(2,3)41-27(38)33(25-20-36(21-34-25)26-17-16-22-13-10-11-15-24(22)35-26)19-23(33)14-12-18-37(28(39)42-31(4,5)6)29(40)43-32(7,8)9/h10-11,13,15-17,20-21,23H,12,14,18-19H2,1-9H3
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n/an/a 58n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326373
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(1,3-thiazol-2-yl...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1nccs1
Show InChI InChI=1S/C24H34N4O6S/c1-22(2,3)33-20(30)28(21(31)34-23(4,5)6)11-8-9-16-13-24(16,18(29)32-7)17-14-27(15-26-17)19-25-10-12-35-19/h10,12,14-16H,8-9,11,13H2,1-7H3
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n/an/a 58n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326352
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(3,4-difluorophen...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(F)c(F)c1
Show InChI InChI=1S/C27H35F2N3O6/c1-25(2,3)37-23(34)32(24(35)38-26(4,5)6)12-8-9-17-14-27(17,22(33)36-7)21-15-31(16-30-21)18-10-11-19(28)20(29)13-18/h10-11,13,15-17H,8-9,12,14H2,1-7H3
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n/an/a 61n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326380
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(5-chloropyridin-...)
Show SMILES CC(C)(C)OC(=O)NCCCC1CC1(C#N)c1cn(cn1)-c1ccc(Cl)cn1
Show InChI InChI=1S/C20H24ClN5O2/c1-19(2,3)28-18(27)23-8-4-5-14-9-20(14,12-22)16-11-26(13-25-16)17-7-6-15(21)10-24-17/h6-7,10-11,13-14H,4-5,8-9H2,1-3H3,(H,23,27)
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n/an/a 63n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326354
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(3-chlorophenyl)-...)
Show SMILES CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1cccc(Cl)c1
Show InChI InChI=1S/C28H38ClN3O6/c1-8-36-23(33)28(22-17-31(18-30-22)21-13-9-12-20(29)15-21)16-19(28)11-10-14-32(24(34)37-26(2,3)4)25(35)38-27(5,6)7/h9,12-13,15,17-19H,8,10-11,14,16H2,1-7H3
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n/an/a 70n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326400
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(6-methylpyridin-...)
Show SMILES Cc1cccc(n1)-n1cnc(c1)C1(CC1CCCN)C(O)=O
Show InChI InChI=1S/C16H20N4O2/c1-11-4-2-6-14(19-11)20-9-13(18-10-20)16(15(21)22)8-12(16)5-3-7-17/h2,4,6,9-10,12H,3,5,7-8,17H2,1H3,(H,21,22)
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n/an/a 73n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326338
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-(1-propyl-1H-imidazo...)
Show SMILES CCCn1cnc(c1)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC
Show InChI InChI=1S/C24H39N3O6/c1-9-12-26-15-18(25-16-26)24(19(28)31-8)14-17(24)11-10-13-27(20(29)32-22(2,3)4)21(30)33-23(5,6)7/h15-17H,9-14H2,1-8H3
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n/an/a 97n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326359
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-(1-pyridin-3-yl-1H-i...)
Show SMILES CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1cccnc1
Show InChI InChI=1S/C27H38N4O6/c1-8-35-22(32)27(21-17-30(18-29-21)20-12-9-13-28-16-20)15-19(27)11-10-14-31(23(33)36-25(2,3)4)24(34)37-26(5,6)7/h9,12-13,16-19H,8,10-11,14-15H2,1-7H3
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n/an/a 98n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326349
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-{1-[(E)-2-phenylviny...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(\C=C\c2ccccc2)cn1
Show InChI InChI=1S/C29H39N3O6/c1-27(2,3)37-25(34)32(26(35)38-28(4,5)6)16-11-14-22-18-29(22,24(33)36-7)23-19-31(20-30-23)17-15-21-12-9-8-10-13-21/h8-10,12-13,15,17,19-20,22H,11,14,16,18H2,1-7H3/b17-15+
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n/an/a 99n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326402
PNG
((1S,2R)-2-[(2R)-2-(Aminomethyl)pentyl]-1-(1-pyridi...)
Show SMILES CCC[C@@H](CN)C[C@@H]1C[C@@]1(C(O)=O)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C18H24N4O2/c1-2-5-13(10-19)8-14-9-18(14,17(23)24)15-11-22(12-21-15)16-6-3-4-7-20-16/h3-4,6-7,11-14H,2,5,8-10,19H2,1H3,(H,23,24)/t13-,14-,18+/m1/s1
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n/an/a>100n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326372
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(2-thienyl)-1H-im...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1cccs1
Show InChI InChI=1S/C25H35N3O6S/c1-23(2,3)33-21(30)28(22(31)34-24(4,5)6)12-8-10-17-14-25(17,20(29)32-7)18-15-27(16-26-18)19-11-9-13-35-19/h9,11,13,15-17H,8,10,12,14H2,1-7H3
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n/an/a 100n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326362
PNG
((1S,2R)-2-(3-Aminopropyl)-1-[1-(3,3-dimethylbutyl)...)
Show SMILES COC(=O)[C@@]1(C[C@@H]1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(CCC(C)(C)C)cn1
Show InChI InChI=1S/C27H45N3O6/c1-24(2,3)13-15-29-17-20(28-18-29)27(21(31)34-10)16-19(27)12-11-14-30(22(32)35-25(4,5)6)23(33)36-26(7,8)9/h17-19H,11-16H2,1-10H3/t19-,27+/m0/s1
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DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326348
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-{1-[4-(trifluorometh...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C28H36F3N3O6/c1-25(2,3)39-23(36)34(24(37)40-26(4,5)6)14-8-9-19-15-27(19,22(35)38-7)21-16-33(17-32-21)20-12-10-18(11-13-20)28(29,30)31/h10-13,16-17,19H,8-9,14-15H2,1-7H3
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n/an/a 140n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326355
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(2-chlorophenyl)-...)
Show SMILES CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccccc1Cl
Show InChI InChI=1S/C28H38ClN3O6/c1-8-36-23(33)28(22-17-31(18-30-22)21-14-10-9-13-20(21)29)16-19(28)12-11-15-32(24(34)37-26(2,3)4)25(35)38-27(5,6)7/h9-10,13-14,17-19H,8,11-12,15-16H2,1-7H3
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n/an/a 140n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326358
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-(1-pyridin-4-yl-1H-i...)
Show SMILES CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccncc1
Show InChI InChI=1S/C27H38N4O6/c1-8-35-22(32)27(21-17-30(18-29-21)20-11-13-28-14-12-20)16-19(27)10-9-15-31(23(33)36-25(2,3)4)24(34)37-26(5,6)7/h11-14,17-19H,8-10,15-16H2,1-7H3
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n/an/a 170n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326387
PNG
((1R*,2R*)-2-(3-Amino-2,2-dimethylpropyl)-1-(1-phen...)
Show SMILES CC(C)(CN)CC1CC1(C(O)=O)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C18H23N3O2/c1-17(2,11-19)8-13-9-18(13,16(22)23)15-10-21(12-20-15)14-6-4-3-5-7-14/h3-7,10,12-13H,8-9,11,19H2,1-2H3,(H,22,23)
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n/an/a>300n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326344
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(2-methylphenyl)-...)
Show SMILES COC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccccc1C
Show InChI InChI=1S/C28H39N3O6/c1-19-12-9-10-14-21(19)30-17-22(29-18-30)28(23(32)35-8)16-20(28)13-11-15-31(24(33)36-26(2,3)4)25(34)37-27(5,6)7/h9-10,12,14,17-18,20H,11,13,15-16H2,1-8H3
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n/an/a>300n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326370
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(6-hydroxypyridin...)
Show SMILES CCOC(=O)C1(CC1CCCNC(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(Br)cn1
Show InChI InChI=1S/C22H29BrN4O4/c1-5-30-19(28)22(11-15(22)7-6-10-24-20(29)31-21(2,3)4)17-13-27(14-26-17)18-9-8-16(23)12-25-18/h8-9,12-15H,5-7,10-11H2,1-4H3,(H,24,29)
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n/an/a 340n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326396
PNG
((1S,2R)-2-[(2R)-2-(Aminomethyl)butyl]-1-(1-pyridin...)
Show SMILES CC[C@@H](CN)C[C@@H]1C[C@@]1(C(O)=O)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C17H22N4O2/c1-2-12(9-18)7-13-8-17(13,16(22)23)14-10-21(11-20-14)15-5-3-4-6-19-15/h3-6,10-13H,2,7-9,18H2,1H3,(H,22,23)/t12-,13-,17+/m1/s1
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n/an/a 360n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326337
PNG
((1R*,2R*)-2-(3-Aminopropyl)-1-[1-(3,3-dimethylbuty...)
Show SMILES CC(C)(C)CCn1cnc(c1)[C@]1(C[C@H]1CCCN)C(O)=O
Show InChI InChI=1S/C16H27N3O2/c1-15(2,3)6-8-19-10-13(18-11-19)16(14(20)21)9-12(16)5-4-7-17/h10-12H,4-9,17H2,1-3H3,(H,20,21)/t12-,16-/m1/s1
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n/an/a 420n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326392
PNG
((1S,2R)-2-[(2S)-3-Amino-2-methylpropyl]-1-(1-pyrid...)
Show SMILES C[C@H](CN)C[C@@H]1C[C@@]1(C(O)=O)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C16H20N4O2/c1-11(8-17)6-12-7-16(12,15(21)22)13-9-20(10-19-13)14-4-2-3-5-18-14/h2-5,9-12H,6-8,17H2,1H3,(H,21,22)/t11-,12+,16-/m0/s1
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n/an/a 490n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326394
PNG
((1S,2R)-2-[(2R)-3-Amino-2-methylpropyl]-1-[1-(5-me...)
Show SMILES C[C@@H](CN)C[C@@H]1C[C@@]1(C(O)=O)c1cn(cn1)-c1ccc(C)cn1
Show InChI InChI=1S/C17H22N4O2/c1-11-3-4-15(19-8-11)21-9-14(20-10-21)17(16(22)23)6-13(17)5-12(2)7-18/h3-4,8-10,12-13H,5-7,18H2,1-2H3,(H,22,23)/t12-,13-,17+/m1/s1
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n/an/a 500n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326369
PNG
((1R*,2S*)-2-(3-Amino-2-methylpropyl)-1-{1-[4-(meth...)
Show SMILES COC(=O)C1(CC1CC(C)CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C29H41N3O8S/c1-19(16-32(25(34)39-27(2,3)4)26(35)40-28(5,6)7)14-20-15-29(20,24(33)38-8)23-17-31(18-30-23)21-10-12-22(13-11-21)41(9,36)37/h10-13,17-20H,14-16H2,1-9H3
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n/an/a 930n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326390
PNG
((1S,2R)-2-[(2R)-3-Amino-2-methylpropyl]-1-(1-pyrid...)
Show SMILES C[C@@H](CN)C[C@@H]1C[C@@]1(C(O)=O)c1cn(cn1)-c1ccccn1
Show InChI InChI=1S/C16H20N4O2/c1-11(8-17)6-12-7-16(12,15(21)22)13-9-20(10-19-13)14-4-2-3-5-18-14/h2-5,9-12H,6-8,17H2,1H3,(H,21,22)/t11-,12-,16+/m1/s1
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n/an/a>3.00E+3n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326364
PNG
((1S,2R)-2-(3-Aminopropyl)-1-(1-phenyl-1H-imidazol-...)
Show SMILES COC(=O)[C@@]1(C[C@@H]1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C27H37N3O6/c1-25(2,3)35-23(32)30(24(33)36-26(4,5)6)15-11-12-19-16-27(19,22(31)34-7)21-17-29(18-28-21)20-13-9-8-10-14-20/h8-10,13-14,17-19H,11-12,15-16H2,1-7H3/t19-,27+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326361
PNG
(Ethyl (1R*,2S*)-2-(3-aminopropyl)-1-[1-(4-methylph...)
Show SMILES CCOC(=O)C1(CC1CCCN)c1cn(cn1)-c1ccc(C)cc1
Show InChI InChI=1S/C19H25N3O2/c1-3-24-18(23)19(11-15(19)5-4-10-20)17-12-22(13-21-17)16-8-6-14(2)7-9-16/h6-9,12-13,15H,3-5,10-11,20H2,1-2H3
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n/an/a 1.00E+4n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%