BindingDB logo
myBDB logout

Patent code US9663460

Compile Data Set for Download or QSAR

Found 209 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327215
PNG
(4-chloro-N-[5-chloro-2-(methylsulfonyl)phenyl]-3-(...)
Show SMILES CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C14H10Cl2F3NO4S2/c1-25(21,22)13-5-2-8(15)6-12(13)20-26(23,24)9-3-4-11(16)10(7-9)14(17,18)19/h2-7,20H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 64n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327227
PNG
(3-{[4-chloro-2-({[4-chloro-3-(trifluoromethyl)phen...)
Show SMILES CC(C)NC(=O)CCSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C19H19Cl2F3N2O3S2/c1-11(2)25-18(27)7-8-30-17-6-3-12(20)9-16(17)26-31(28,29)13-4-5-15(21)14(10-13)19(22,23)24/h3-6,9-11,26H,7-8H2,1-2H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.03E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327228
PNG
(3-{[4-chloro-2-({[4-chloro-3-(trifluoromethyl)phen...)
Show SMILES CN(C)C(=O)CCSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C18H17Cl2F3N2O3S2/c1-25(2)17(26)7-8-29-16-6-3-11(19)9-15(16)24-30(27,28)12-4-5-14(20)13(10-12)18(21,22)23/h3-6,9-10,24H,7-8H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 506n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327230
PNG
(3-{[4-chloro-2-({[4-chloro-3-(trifluoromethyl)-phe...)
Show SMILES CN(C)C(=O)CCS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C18H17Cl2F3N2O4S2/c1-25(2)17(26)7-8-30(27)16-6-3-11(19)9-15(16)24-31(28,29)12-4-5-14(20)13(10-12)18(21,22)23/h3-6,9-10,24H,7-8H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 96n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327237
PNG
(4-chloro-N-[5-chloro-2-(ethylthio)phenyl]-3-(trifl...)
Show SMILES CCSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C15H12Cl2F3NO2S2/c1-2-24-14-6-3-9(16)7-13(14)21-25(22,23)10-4-5-12(17)11(8-10)15(18,19)20/h3-8,21H,2H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 193n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327240
PNG
(N-[5-chloro-2-(methylthio)phenyl]-1-benzofuran-2-s...)
Show SMILES CSc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C15H12ClNO3S2/c1-21-14-7-6-11(16)9-12(14)17-22(18,19)15-8-10-4-2-3-5-13(10)20-15/h2-9,17H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 26n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327249
PNG
(4-chloro-N-[5-chloro-2-(methylsulfonyl)phenyl]benz...)
Show SMILES CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C13H11Cl2NO4S2/c1-21(17,18)13-7-4-10(15)8-12(13)16-22(19,20)11-5-2-9(14)3-6-11/h2-8,16H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 155n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327255
PNG
(2-{[4-chloro-2-({[4-chloro-3-(trifluoromethyl)-phe...)
Show SMILES CNC(=O)CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C16H13Cl2F3N2O5S2/c1-22-15(24)8-29(25,26)14-5-2-9(17)6-13(14)23-30(27,28)10-3-4-12(18)11(7-10)16(19,20)21/h2-7,23H,8H2,1H3,(H,22,24)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 469n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327268
PNG
(4-chloro-N-[5-chloro-2-(methylthio)phenyl]-2-fluor...)
Show SMILES CSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)cc1F
Show InChI InChI=1S/C13H10Cl2FNO2S2/c1-20-12-4-2-9(15)7-11(12)17-21(18,19)13-5-3-8(14)6-10(13)16/h2-7,17H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 25n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327271
PNG
(3-chloro-N-[5-chloro-2-(methylsulfinyl)phenyl]-2-f...)
Show SMILES CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc(Cl)c1F
Show InChI InChI=1S/C13H10Cl2FNO3S2/c1-21(18)11-6-5-8(14)7-10(11)17-22(19,20)12-4-2-3-9(15)13(12)16/h2-7,17H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 61n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327279
PNG
(4-chloro-N-{5-chloro-2-[(1H-imidazol-4-ylmethyl)su...)
Show SMILES FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)Nc1cc(Cl)ccc1S(=O)Cc1c[nH]cn1
Show InChI InChI=1S/C17H12Cl2F3N3O3S2/c18-10-1-4-16(29(26)8-11-7-23-9-24-11)15(5-10)25-30(27,28)12-2-3-14(19)13(6-12)17(20,21)22/h1-7,9,25H,8H2,(H,23,24)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 158n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327282
PNG
(N-{5-chloro-2-[(1H-imidazol-2-ylmethyl)sulfinyl]-p...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)Cc1ncc[nH]1
Show InChI InChI=1S/C18H14ClN3O4S2/c19-13-5-6-16(27(23)11-17-20-7-8-21-17)14(10-13)22-28(24,25)18-9-12-3-1-2-4-15(12)26-18/h1-10,22H,11H2,(H,20,21)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.90E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327314
PNG
(N-[5-chloro-2-(methylthio)phenyl]-4-iodobenzenesul...)
Show SMILES CSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(I)cc1
Show InChI InChI=1S/C13H11ClINO2S2/c1-19-13-7-2-9(14)8-12(13)16-20(17,18)11-5-3-10(15)4-6-11/h2-8,16H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.03E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327324
PNG
(N-{5-chloro-2-[(pyridin-2-ylmethyl)thio]phenyl}-1-...)
Show SMILES Clc1ccc(SCc2ccccn2)c(NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C20H15ClN2O3S2/c21-15-8-9-19(27-13-16-6-3-4-10-22-16)17(12-15)23-28(24,25)20-11-14-5-1-2-7-18(14)26-20/h1-12,23H,13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 35n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327326
PNG
(N-{5-chloro-2-[(pyridin-3-ylmethyl)sulfinyl]phenyl...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)Cc1cccnc1
Show InChI InChI=1S/C20H15ClN2O4S2/c21-16-7-8-19(28(24)13-14-4-3-9-22-12-14)17(11-16)23-29(25,26)20-10-15-5-1-2-6-18(15)27-20/h1-12,23H,13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 76n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327333
PNG
(N-(2-{[(5-amino-1H-pyrazol-3-yl)methyl]sulfinyl}-5...)
Show SMILES Nc1cc(CS(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)n[nH]1
Show InChI InChI=1S/C18H15ClN4O4S2/c19-12-5-6-16(28(24)10-13-9-17(20)22-21-13)14(8-12)23-29(25,26)18-7-11-3-1-2-4-15(11)27-18/h1-9,23H,10H2,(H3,20,21,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.38E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327342
PNG
(US9663460, Example 148 | tert-butyl {4-[({2-[(1-be...)
Show SMILES CC(C)(C)OC(=O)Nc1cc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)ccn1
Show InChI InChI=1S/C25H24ClN3O5S2/c1-25(2,3)34-24(30)28-22-12-16(10-11-27-22)15-35-21-9-8-18(26)14-19(21)29-36(31,32)23-13-17-6-4-5-7-20(17)33-23/h4-14,29H,15H2,1-3H3,(H,27,28,30)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327348
PNG
(N-(2-{[(2-amino-1-oxidopyridin-4-yl)methyl]-sulfon...)
Show SMILES Nc1cc(CS(=O)(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)cc[n+]1[O-]
Show InChI InChI=1S/C20H16ClN3O6S2/c21-15-5-6-18(31(26,27)12-13-7-8-24(25)19(22)9-13)16(11-15)23-32(28,29)20-10-14-3-1-2-4-17(14)30-20/h1-11,23H,12,22H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.96E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327357
PNG
(N-(2-{[(5-amino-4H-1,2,4-triazol-3-yl)methyl]thio}...)
Show SMILES Nc1nnc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)[nH]1
Show InChI InChI=1S/C17H14ClN5O3S2/c18-11-5-6-14(27-9-15-20-17(19)22-21-15)12(8-11)23-28(24,25)16-7-10-3-1-2-4-13(10)26-16/h1-8,23H,9H2,(H3,19,20,21,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 32n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327389
PNG
(N-{2-[(3-nitrobenzyl)sulfinyl]phenyl}-1-benzofuran...)
Show SMILES [O-][N+](=O)c1cccc(CS(=O)c2ccccc2NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C21H16N2O6S2/c24-23(25)17-8-5-6-15(12-17)14-30(26)20-11-4-2-9-18(20)22-31(27,28)21-13-16-7-1-3-10-19(16)29-21/h1-13,22H,14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 653n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327395
PNG
(N-{5-chloro-2-[(4-nitrobenzyl)thio]phenyl}-1-benzo...)
Show SMILES [O-][N+](=O)c1ccc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C21H15ClN2O5S2/c22-16-7-10-20(30-13-14-5-8-17(9-6-14)24(25)26)18(12-16)23-31(27,28)21-11-15-3-1-2-4-19(15)29-21/h1-12,23H,13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 147n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327413
PNG
(N-{2-[(3-aminobenzyl)thio]-5-chlorophenyl}-3-chlor...)
Show SMILES Nc1cccc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cccc(Cl)c2)c1
Show InChI InChI=1S/C19H16Cl2N2O2S2/c20-14-4-2-6-17(10-14)27(24,25)23-18-11-15(21)7-8-19(18)26-12-13-3-1-5-16(22)9-13/h1-11,23H,12,22H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.46E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327222
PNG
(4-chloro-N-{5-chloro-2-[(pyridin-2-ylmethyl)thio]-...)
Show SMILES FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)Nc1cc(Cl)ccc1SCc1ccccn1
Show InChI InChI=1S/C19H13Cl2F3N2O2S2/c20-12-4-7-18(29-11-13-3-1-2-8-25-13)17(9-12)26-30(27,28)14-5-6-16(21)15(10-14)19(22,23)24/h1-10,26H,11H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 199n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327234
PNG
(4-chloro-N-{5-chloro-2-[(3-nitrophenyl)sulfinyl]-p...)
Show SMILES [O-][N+](=O)c1cccc(c1)S(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C19H11Cl2F3N2O5S2/c20-11-4-7-18(32(29)13-3-1-2-12(9-13)26(27)28)17(8-11)25-33(30,31)14-5-6-16(21)15(10-14)19(22,23)24/h1-10,25H
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 509n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327235
PNG
(4-chloro-N-{5-chloro-2-[(3-hydroxycyclopentyl)sulf...)
Show SMILES OC1CCC(C1)S(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C18H16Cl2F3NO4S2/c19-10-1-6-17(29(26)12-3-2-11(25)8-12)16(7-10)24-30(27,28)13-4-5-15(20)14(9-13)18(21,22)23/h1,4-7,9,11-12,24-25H,2-3,8H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 107n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327242
PNG
(N-[5-chloro-2-(methylsulfonyl)phenyl]-1-benzofuran...)
Show SMILES CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C15H12ClNO5S2/c1-23(18,19)14-7-6-11(16)9-12(14)17-24(20,21)15-8-10-4-2-3-5-13(10)22-15/h2-9,17H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 42n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327248
PNG
(4-chloro-N-[5-chloro-2-(methylsulfinyl)phenyl]benz...)
Show SMILES CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C13H11Cl2NO3S2/c1-20(17)13-7-4-10(15)8-12(13)16-21(18,19)11-5-2-9(14)3-6-11/h2-8,16H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 62n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327253
PNG
(2-{[4-chloro-2-({[4-chloro-3-(trifluoromethyl)-phe...)
Show SMILES CN(C)C(=O)CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C17H15Cl2F3N2O5S2/c1-24(2)16(25)9-30(26,27)15-6-3-10(18)7-14(15)23-31(28,29)11-4-5-13(19)12(8-11)17(20,21)22/h3-8,23H,9H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 462n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327256
PNG
(N-{2-[(2-aminoethyl)thio]-5-chlorophenyl}-4-chloro...)
Show SMILES NCCSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C15H13Cl2F3N2O2S2/c16-9-1-4-14(25-6-5-21)13(7-9)22-26(23,24)10-2-3-12(17)11(8-10)15(18,19)20/h1-4,7-8,22H,5-6,21H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.07E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327261
PNG
(N-[5-chloro-2-(methylsulfinyl)phenyl]-3-nitro-4-(t...)
Show SMILES CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(c(c1)[N+]([O-])=O)C(F)(F)F
Show InChI InChI=1S/C14H10ClF3N2O5S2/c1-26(23)13-5-2-8(15)6-11(13)19-27(24,25)9-3-4-10(14(16,17)18)12(7-9)20(21)22/h2-7,19H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 54n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327269
PNG
(3-chloro-N-[5-chloro-2-(methylthio)phenyl]-2-fluor...)
Show SMILES CSc1ccc(Cl)cc1NS(=O)(=O)c1cccc(Cl)c1F
Show InChI InChI=1S/C13H10Cl2FNO2S2/c1-20-11-6-5-8(14)7-10(11)17-21(18,19)12-4-2-3-9(15)13(12)16/h2-7,17H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.92E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327275
PNG
(4-chloro-N-{5-chloro-2-[(1H-imidazol-2-ylmethyl)th...)
Show SMILES FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)Nc1cc(Cl)ccc1SCc1ncc[nH]1
Show InChI InChI=1S/C17H12Cl2F3N3O2S2/c18-10-1-4-15(28-9-16-23-5-6-24-16)14(7-10)25-29(26,27)11-2-3-13(19)12(8-11)17(20,21)22/h1-8,25H,9H2,(H,23,24)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 190n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327284
PNG
(N-{5-chloro-2-[(1H-imidazol-4-ylmethyl)thio]-pheny...)
Show SMILES Clc1ccc(SCc2c[nH]cn2)c(NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C18H14ClN3O3S2/c19-13-5-6-17(26-10-14-9-20-11-21-14)15(8-13)22-27(23,24)18-7-12-3-1-2-4-16(12)25-18/h1-9,11,22H,10H2,(H,20,21)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327285
PNG
(N-{5-chloro-2-[(1H-imidazol-4-ylmethyl)-sulfinyl]p...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)Cc1c[nH]cn1
Show InChI InChI=1S/C18H14ClN3O4S2/c19-13-5-6-17(27(23)10-14-9-20-11-21-14)15(8-13)22-28(24,25)18-7-12-3-1-2-4-16(12)26-18/h1-9,11,22H,10H2,(H,20,21)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 296n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327292
PNG
(N-[2-({2-[(aminocarbonyl)amino]ethyl}sulfonyl)-5-c...)
Show SMILES NC(=O)NCCS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C17H16ClN3O6S2/c18-12-5-6-15(28(23,24)8-7-20-17(19)22)13(10-12)21-29(25,26)16-9-11-3-1-2-4-14(11)27-16/h1-6,9-10,21H,7-8H2,(H3,19,20,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327305
PNG
(5-chloro-N-[5-chloro-2-(methylsulfonyl)phenyl]-1-b...)
Show SMILES CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cc2cc(Cl)ccc2o1
Show InChI InChI=1S/C15H11Cl2NO5S2/c1-24(19,20)14-5-3-11(17)8-12(14)18-25(21,22)15-7-9-6-10(16)2-4-13(9)23-15/h2-8,18H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.05E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327315
PNG
(4-bromo-N-[5-chloro-2-(methylsulfinyl)phenyl]benze...)
Show SMILES CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C13H11BrClNO3S2/c1-20(17)13-7-4-10(15)8-12(13)16-21(18,19)11-5-2-9(14)3-6-11/h2-8,16H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 116n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327317
PNG
(4-bromo-N-[5-chloro-2-(methylsulfonyl)phenyl]benze...)
Show SMILES CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C13H11BrClNO4S2/c1-21(17,18)13-7-4-10(15)8-12(13)16-22(19,20)11-5-2-9(14)3-6-11/h2-8,16H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 403n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327323
PNG
(N-(2-{[(2-amino-1,3-thiazol-4-yl)methyl]sulfonyl}-...)
Show SMILES Nc1nc(CS(=O)(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)cs1
Show InChI InChI=1S/C18H14ClN3O5S3/c19-12-5-6-16(29(23,24)10-13-9-28-18(20)21-13)14(8-12)22-30(25,26)17-7-11-3-1-2-4-15(11)27-17/h1-9,22H,10H2,(H2,20,21)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 83n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327327
PNG
(N-(5-chloro-2-{[(1-oxidopyridin-3-yl)methyl]-sulfi...)
Show SMILES [O-][n+]1cccc(CS(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C20H15ClN2O5S2/c21-16-7-8-19(29(25)13-14-4-3-9-23(24)12-14)17(11-16)22-30(26,27)20-10-15-5-1-2-6-18(15)28-20/h1-12,22H,13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 646n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327350
PNG
(N-{2-[(3-aminobenzyl)sulfinyl]-5-chlorophenyl}-1-b...)
Show SMILES Nc1cccc(CS(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C21H17ClN2O4S2/c22-16-8-9-20(29(25)13-14-4-3-6-17(23)10-14)18(12-16)24-30(26,27)21-11-15-5-1-2-7-19(15)28-21/h1-12,24H,13,23H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 39n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327361
PNG
(3-[(4-chloro-2-{[(4-chloro-2-fluorophenyl)sulfonyl...)
Show SMILES CN(C)C(=O)CCS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)cc1F
Show InChI InChI=1S/C17H17Cl2FN2O4S2/c1-22(2)17(23)7-8-27(24)15-5-3-12(19)10-14(15)21-28(25,26)16-6-4-11(18)9-13(16)20/h3-6,9-10,21H,7-8H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 221n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327362
PNG
(3-[(4-chloro-2-{[(4-chloro-2-fluorophenyl)sulfonyl...)
Show SMILES CN(C)C(=O)CCS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)cc1F
Show InChI InChI=1S/C17H17Cl2FN2O5S2/c1-22(2)17(23)7-8-28(24,25)16-6-4-12(19)10-14(16)21-29(26,27)15-5-3-11(18)9-13(15)20/h3-6,9-10,21H,7-8H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 211n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327369
PNG
(N-(5-chloro-2-{[2-(3,5-dimethyl-1H-pyrazol-4-yl)et...)
Show SMILES Cc1n[nH]c(C)c1CCSc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C21H20ClN3O3S2/c1-13-17(14(2)24-23-13)9-10-29-20-8-7-16(22)12-18(20)25-30(26,27)21-11-15-5-3-4-6-19(15)28-21/h3-8,11-12,25H,9-10H2,1-2H3,(H,23,24)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 279n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327378
PNG
(N-[2-(benzylthio)-5-chlorophenyl]-1-benzofuran-2-s...)
Show SMILES Clc1ccc(SCc2ccccc2)c(NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C21H16ClNO3S2/c22-17-10-11-20(27-14-15-6-2-1-3-7-15)18(13-17)23-28(24,25)21-12-16-8-4-5-9-19(16)26-21/h1-13,23H,14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 129n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327379
PNG
(N-[2-(benzylsulfinyl)-5-chlorophenyl]-1-benzofuran...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)Cc1ccccc1
Show InChI InChI=1S/C21H16ClNO4S2/c22-17-10-11-20(28(24)14-15-6-2-1-3-7-15)18(13-17)23-29(25,26)21-12-16-8-4-5-9-19(16)27-21/h1-13,23H,14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 27n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327397
PNG
(N-{5-chloro-2-[(4-nitrobenzyl)sulfonyl]phenyl}-1-b...)
Show SMILES [O-][N+](=O)c1ccc(CS(=O)(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C21H15ClN2O7S2/c22-16-7-10-20(32(27,28)13-14-5-8-17(9-6-14)24(25)26)18(12-16)23-33(29,30)21-11-15-3-1-2-4-19(15)31-21/h1-12,23H,13H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.16E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327408
PNG
(N-{5-chloro-2-[(pyrimidin-2-ylmethyl)thio]-phenyl}...)
Show SMILES Clc1ccc(SCc2ncccn2)c(NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C19H14ClN3O3S2/c20-14-6-7-17(27-12-18-21-8-3-9-22-18)15(11-14)23-28(24,25)19-10-13-4-1-2-5-16(13)26-19/h1-11,23H,12H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 549n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327420
PNG
(N-[2-(benzylthio)-5-cyanophenyl]-1-benzofuran-2-su...)
Show SMILES O=S(=O)(Nc1cc(ccc1SCc1ccccc1)C#N)c1cc2ccccc2o1
Show InChI InChI=1S/C22H16N2O3S2/c23-14-17-10-11-21(28-15-16-6-2-1-3-7-16)19(12-17)24-29(25,26)22-13-18-8-4-5-9-20(18)27-22/h1-13,24H,15H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.84E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327238
PNG
(4-chloro-N-[5-chloro-2-(ethylsulfinyl)phenyl]-3-(t...)
Show SMILES CCS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C15H12Cl2F3NO3S2/c1-2-25(22)14-6-3-9(16)7-13(14)21-26(23,24)10-4-5-12(17)11(8-10)15(18,19)20/h3-8,21H,2H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 50n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 209 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%