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Patent code US9663460

Compile Data Set for Download or QSAR

Found 209 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327214
PNG
(4-chloro-N-[5-chloro-2-(methylsulfinyl)phenyl]-3-(...)
Show SMILES CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C14H10Cl2F3NO3S2/c1-24(21)13-5-2-8(15)6-12(13)20-25(22,23)9-3-4-11(16)10(7-9)14(17,18)19/h2-7,20H,1H3
PDB

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UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 14n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327241
PNG
(N-[5-chloro-2-(methylsulfinyl)phenyl]-1-benzofuran...)
Show SMILES CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C15H12ClNO4S2/c1-22(18)14-7-6-11(16)9-12(14)17-23(19,20)15-8-10-4-2-3-5-13(10)21-15/h2-9,17H,1H3
PDB

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UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327250
PNG
(4-chloro-N-[5-chloro-2-(methylsulfinyl)phenyl]-3-m...)
Show SMILES Cc1cc(ccc1Cl)S(=O)(=O)Nc1cc(Cl)ccc1S(C)=O
Show InChI InChI=1S/C14H13Cl2NO3S2/c1-9-7-11(4-5-12(9)16)22(19,20)17-13-8-10(15)3-6-14(13)21(2)18/h3-8,17H,1-2H3
PDB

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US Patent
n/an/a 44n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327265
PNG
(N-[5-chloro-2-(methylthio)phenyl]furan-2-sulfonami...)
Show SMILES CSc1ccc(Cl)cc1NS(=O)(=O)c1ccco1
Show InChI InChI=1S/C11H10ClNO3S2/c1-17-10-5-4-8(12)7-9(10)13-18(14,15)11-3-2-6-16-11/h2-7,13H,1H3
PDB

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US Patent
n/an/a 940n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327266
PNG
(N-[5-chloro-2-(methylsulfinyl)phenyl]furan-2-sulfo...)
Show SMILES CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccco1
Show InChI InChI=1S/C11H10ClNO4S2/c1-18(14)10-5-4-8(12)7-9(10)13-19(15,16)11-3-2-6-17-11/h2-7,13H,1H3
PDB

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US Patent
n/an/a 2.32E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327289
PNG
(3-({2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorop...)
Show SMILES CN(C)C(=O)CCS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C19H19ClN2O6S2/c1-22(2)18(23)9-10-29(24,25)17-8-7-14(20)12-15(17)21-30(26,27)19-11-13-5-3-4-6-16(13)28-19/h3-8,11-12,21H,9-10H2,1-2H3
PDB

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US Patent
n/an/a 76n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327307
PNG
(N-{5-chloro-2-[(1H-pyrazol-3-ylmethyl)sulfinyl]-ph...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)Cc1cc[nH]n1
Show InChI InChI=1S/C18H14ClN3O4S2/c19-13-5-6-17(27(23)11-14-7-8-20-21-14)15(10-13)22-28(24,25)18-9-12-3-1-2-4-16(12)26-18/h1-10,22H,11H2,(H,20,21)
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n/an/a 634n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327314
PNG
(N-[5-chloro-2-(methylthio)phenyl]-4-iodobenzenesul...)
Show SMILES CSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(I)cc1
Show InChI InChI=1S/C13H11ClINO2S2/c1-19-13-7-2-9(14)8-12(13)16-20(17,18)11-5-3-10(15)4-6-11/h2-8,16H,1H3
PDB

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US Patent
n/an/a 2.03E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327315
PNG
(4-bromo-N-[5-chloro-2-(methylsulfinyl)phenyl]benze...)
Show SMILES CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C13H11BrClNO3S2/c1-20(17)13-7-4-10(15)8-12(13)16-21(18,19)11-5-2-9(14)3-6-11/h2-8,16H,1H3
PDB

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n/an/a 116n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327318
PNG
(N-[5-chloro-2-(methylsulfonyl)phenyl]-4-iodobenzen...)
Show SMILES CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(I)cc1
Show InChI InChI=1S/C13H11ClINO4S2/c1-21(17,18)13-7-2-9(14)8-12(13)16-22(19,20)11-5-3-10(15)4-6-11/h2-8,16H,1H3
PDB

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US Patent
n/an/a 1.07E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327319
PNG
(US9663460, Example 122 | tert-butyl {4-[({2-[(1-be...)
Show SMILES CC(C)(C)OC(=O)Nc1nc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)cs1
Show InChI InChI=1S/C23H22ClN3O5S3/c1-23(2,3)32-22(28)26-21-25-16(13-34-21)12-33-19-9-8-15(24)11-17(19)27-35(29,30)20-10-14-6-4-5-7-18(14)31-20/h4-11,13,27H,12H2,1-3H3,(H,25,26,28)
PDB

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US Patent
n/an/a 2.43E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327322
PNG
(N-(2-{[(2-amino-1,3-thiazol-4-yl)methyl]sulfinyl}-...)
Show SMILES Nc1nc(CS(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)cs1
Show InChI InChI=1S/C18H14ClN3O4S3/c19-12-5-6-16(28(23)10-13-9-27-18(20)21-13)14(8-12)22-29(24,25)17-7-11-3-1-2-4-15(11)26-17/h1-9,22H,10H2,(H2,20,21)
PDB

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US Patent
n/an/a 262n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327324
PNG
(N-{5-chloro-2-[(pyridin-2-ylmethyl)thio]phenyl}-1-...)
Show SMILES Clc1ccc(SCc2ccccn2)c(NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C20H15ClN2O3S2/c21-15-8-9-19(27-13-16-6-3-4-10-22-16)17(12-15)23-28(24,25)20-11-14-5-1-2-7-18(14)26-20/h1-12,23H,13H2
PDB

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n/an/a 35n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327329
PNG
(N-(5-chloro-2-{[(1-oxidopyridin-3-yl)methyl]-sulfo...)
Show SMILES [O-][n+]1cccc(CS(=O)(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C20H15ClN2O6S2/c21-16-7-8-19(30(25,26)13-14-4-3-9-23(24)12-14)17(11-16)22-31(27,28)20-10-15-5-1-2-6-18(15)29-20/h1-12,22H,13H2
PDB

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US Patent
n/an/a 1.75E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327332
PNG
(N-(2-{[(5-amino-1H-pyrazol-3-yl)methyl]thio}-5-chl...)
Show SMILES Nc1cc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)n[nH]1
Show InChI InChI=1S/C18H15ClN4O3S2/c19-12-5-6-16(27-10-13-9-17(20)22-21-13)14(8-12)23-28(24,25)18-7-11-3-1-2-4-15(11)26-18/h1-9,23H,10H2,(H3,20,21,22)
PDB

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n/an/a 25n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327343
PNG
(N-(2-{[(2-aminopyridin-4-yl)methyl]thio}-5-chlorop...)
Show SMILES Nc1cc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)ccn1
Show InChI InChI=1S/C20H16ClN3O3S2/c21-15-5-6-18(28-12-13-7-8-23-19(22)9-13)16(11-15)24-29(25,26)20-10-14-3-1-2-4-17(14)27-20/h1-11,24H,12H2,(H2,22,23)
PDB

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n/an/a 80n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327347
PNG
(N-(2-{[(2-aminopyridin-4-yl)methyl]sulfonyl}-5-chl...)
Show SMILES Nc1cc(CS(=O)(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)ccn1
Show InChI InChI=1S/C20H16ClN3O5S2/c21-15-5-6-18(30(25,26)12-13-7-8-23-19(22)9-13)16(11-15)24-31(27,28)20-10-14-3-1-2-4-17(14)29-20/h1-11,24H,12H2,(H2,22,23)
PDB

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US Patent
n/an/a 364n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327353
PNG
(N-{5-chloro-2-[(3-hydroxybenzyl)sulfinyl]phenyl}-1...)
Show SMILES Oc1cccc(CS(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C21H16ClNO5S2/c22-16-8-9-20(29(25)13-14-4-3-6-17(24)10-14)18(12-16)23-30(26,27)21-11-15-5-1-2-7-19(15)28-21/h1-12,23-24H,13H2
PDB

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n/an/a 112n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327380
PNG
(N-[2-(benzylsulfonyl)-5-chlorophenyl]-1-benzofuran...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C21H16ClNO5S2/c22-17-10-11-20(29(24,25)14-15-6-2-1-3-7-15)18(13-17)23-30(26,27)21-12-16-8-4-5-9-19(16)28-21/h1-13,23H,14H2
PDB

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n/an/a 34n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327390
PNG
(N-{2-[(3-aminobenzyl)sulfinyl]phenyl}-1-benzofuran...)
Show SMILES Nc1cccc(CS(=O)c2ccccc2NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C21H18N2O4S2/c22-17-8-5-6-15(12-17)14-28(24)20-11-4-2-9-18(20)23-29(25,26)21-13-16-7-1-3-10-19(16)27-21/h1-13,23H,14,22H2
PDB

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n/an/a 58n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327410
PNG
(N-{5-chloro-2-[(pyrimidin-2-ylmethyl)sulfonyl]-phe...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)(=O)Cc1ncccn1
Show InChI InChI=1S/C19H14ClN3O5S2/c20-14-6-7-17(29(24,25)12-18-21-8-3-9-22-18)15(11-14)23-30(26,27)19-10-13-4-1-2-5-16(13)28-19/h1-11,23H,12H2
PDB

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PC sid
UniChem
US Patent
n/an/a 151n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327412
PNG
(N-{2-[(3-aminobenzyl)thio]-5-chlorophenyl}-4-chlor...)
Show SMILES Nc1cccc(CSc2ccc(Cl)cc2NS(=O)(=O)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C19H16Cl2N2O2S2/c20-14-4-7-17(8-5-14)27(24,25)23-18-11-15(21)6-9-19(18)26-12-13-2-1-3-16(22)10-13/h1-11,23H,12,22H2
PDB

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UniChem
US Patent
n/an/a 3.89E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327413
PNG
(N-{2-[(3-aminobenzyl)thio]-5-chlorophenyl}-3-chlor...)
Show SMILES Nc1cccc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cccc(Cl)c2)c1
Show InChI InChI=1S/C19H16Cl2N2O2S2/c20-14-4-2-6-17(10-14)27(24,25)23-18-11-15(21)7-8-19(18)26-12-13-3-1-5-16(22)9-13/h1-11,23H,12,22H2
PDB

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n/an/a 1.46E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327416
PNG
(N-{2-[(3-aminobenzyl)sulfonyl]-5-chlorophenyl}-4-c...)
Show SMILES Nc1cccc(CS(=O)(=O)c2ccc(Cl)cc2NS(=O)(=O)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C19H16Cl2N2O4S2/c20-14-4-7-17(8-5-14)29(26,27)23-18-11-15(21)6-9-19(18)28(24,25)12-13-2-1-3-16(22)10-13/h1-11,23H,12,22H2
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n/an/a 421n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327227
PNG
(3-{[4-chloro-2-({[4-chloro-3-(trifluoromethyl)phen...)
Show SMILES CC(C)NC(=O)CCSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C19H19Cl2F3N2O3S2/c1-11(2)25-18(27)7-8-30-17-6-3-12(20)9-16(17)26-31(28,29)13-4-5-15(21)14(10-13)19(22,23)24/h3-6,9-11,26H,7-8H2,1-2H3,(H,25,27)
PDB

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n/an/a 1.03E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327234
PNG
(4-chloro-N-{5-chloro-2-[(3-nitrophenyl)sulfinyl]-p...)
Show SMILES [O-][N+](=O)c1cccc(c1)S(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C19H11Cl2F3N2O5S2/c20-11-4-7-18(32(29)13-3-1-2-12(9-13)26(27)28)17(8-11)25-33(30,31)14-5-6-16(21)15(10-14)19(22,23)24/h1-10,25H
PDB

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n/an/a 509n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327235
PNG
(4-chloro-N-{5-chloro-2-[(3-hydroxycyclopentyl)sulf...)
Show SMILES OC1CCC(C1)S(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C18H16Cl2F3NO4S2/c19-10-1-6-17(29(26)12-3-2-11(25)8-12)16(7-10)24-30(27,28)13-4-5-15(20)14(9-13)18(21,22)23/h1,4-7,9,11-12,24-25H,2-3,8H2
PDB

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n/an/a 107n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327236
PNG
(4-chloro-N-{5-chloro-2-[(3-hydroxycyclopentyl)sulf...)
Show SMILES OC1CCC(C1)S(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C18H16Cl2F3NO5S2/c19-10-1-6-17(30(26,27)12-3-2-11(25)8-12)16(7-10)24-31(28,29)13-4-5-15(20)14(9-13)18(21,22)23/h1,4-7,9,11-12,24-25H,2-3,8H2
PDB

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n/an/a 76n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327238
PNG
(4-chloro-N-[5-chloro-2-(ethylsulfinyl)phenyl]-3-(t...)
Show SMILES CCS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C15H12Cl2F3NO3S2/c1-2-25(22)14-6-3-9(16)7-13(14)21-26(23,24)10-4-5-12(17)11(8-10)15(18,19)20/h3-8,21H,2H2,1H3
PDB

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n/an/a 50n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327253
PNG
(2-{[4-chloro-2-({[4-chloro-3-(trifluoromethyl)-phe...)
Show SMILES CN(C)C(=O)CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C17H15Cl2F3N2O5S2/c1-24(2)16(25)9-30(26,27)15-6-3-10(18)7-14(15)23-31(28,29)11-4-5-13(19)12(8-11)17(20,21)22/h3-8,23H,9H2,1-2H3
PDB

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n/an/a 462n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327254
PNG
(2-{[4-chloro-2-({[4-chloro-3-(trifluoromethyl)phen...)
Show SMILES CNC(=O)CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C16H13Cl2F3N2O4S2/c1-22-15(24)8-28(25)14-5-2-9(17)6-13(14)23-29(26,27)10-3-4-12(18)11(7-10)16(19,20)21/h2-7,23H,8H2,1H3,(H,22,24)
PDB

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n/an/a 329n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327261
PNG
(N-[5-chloro-2-(methylsulfinyl)phenyl]-3-nitro-4-(t...)
Show SMILES CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(c(c1)[N+]([O-])=O)C(F)(F)F
Show InChI InChI=1S/C14H10ClF3N2O5S2/c1-26(23)13-5-2-8(15)6-11(13)19-27(24,25)9-3-4-10(14(16,17)18)12(7-9)20(21)22/h2-7,19H,1H3
PDB

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n/an/a 54n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327263
PNG
(N-[5-chloro-2-(methylsulfinyl)phenyl]-5-methylfura...)
Show SMILES Cc1ccc(o1)S(=O)(=O)Nc1cc(Cl)ccc1S(C)=O
Show InChI InChI=1S/C12H12ClNO4S2/c1-8-3-6-12(18-8)20(16,17)14-10-7-9(13)4-5-11(10)19(2)15/h3-7,14H,1-2H3
PDB

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n/an/a 194n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327272
PNG
(4-chloro-N-[5-chloro-2-(methylsulfonyl)phenyl]-2-f...)
Show SMILES CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)cc1F
Show InChI InChI=1S/C13H10Cl2FNO4S2/c1-22(18,19)13-5-3-9(15)7-11(13)17-23(20,21)12-4-2-8(14)6-10(12)16/h2-7,17H,1H3
PDB

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n/an/a 171n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327283
PNG
(N-{5-chloro-2-[(1H-imidazol-2-ylmethyl)sulfonyl]-p...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)(=O)Cc1ncc[nH]1
Show InChI InChI=1S/C18H14ClN3O5S2/c19-13-5-6-16(28(23,24)11-17-20-7-8-21-17)14(10-13)22-29(25,26)18-9-12-3-1-2-4-15(12)27-18/h1-10,22H,11H2,(H,20,21)
PDB

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n/an/a 1.35E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327286
PNG
(N-{5-chloro-2-[(1H-imidazol-4-ylmethyl)-sulfonyl]p...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)(=O)Cc1c[nH]cn1
Show InChI InChI=1S/C18H14ClN3O5S2/c19-13-5-6-17(28(23,24)10-14-9-20-11-21-14)15(8-13)22-29(25,26)18-7-12-3-1-2-4-16(12)27-18/h1-9,11,22H,10H2,(H,20,21)
PDB

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n/an/a 81n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327302
PNG
(N-(5-chloro-2-{[(2,6-dioxo-1,2,3,6-tetrahydro-pyri...)
Show SMILES Clc1ccc(SCc2cc(=O)[nH]c(=O)[nH]2)c(NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C19H14ClN3O5S2/c20-12-5-6-16(29-10-13-9-17(24)22-19(25)21-13)14(8-12)23-30(26,27)18-7-11-3-1-2-4-15(11)28-18/h1-9,23H,10H2,(H2,21,22,24,25)
PDB

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n/an/a 2.37E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327304
PNG
(5-chloro-N-[5-chloro-2-(methylsulfinyl)phenyl]-1-b...)
Show SMILES CS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cc2cc(Cl)ccc2o1
Show InChI InChI=1S/C15H11Cl2NO4S2/c1-23(19)14-5-3-11(17)8-12(14)18-24(20,21)15-7-9-6-10(16)2-4-13(9)22-15/h2-8,18H,1H3
PDB

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n/an/a 655n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327309
PNG
(N-(5-chloro-2-{[(2,4-dioxo-1,2,3,4-tetrahydro-pyri...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)Cc1c[nH]c(=O)[nH]c1=O
Show InChI InChI=1S/C19H14ClN3O6S2/c20-13-5-6-16(30(26)10-12-9-21-19(25)22-18(12)24)14(8-13)23-31(27,28)17-7-11-3-1-2-4-15(11)29-17/h1-9,23H,10H2,(H2,21,22,24,25)
PDB

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n/an/a 3.08E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327323
PNG
(N-(2-{[(2-amino-1,3-thiazol-4-yl)methyl]sulfonyl}-...)
Show SMILES Nc1nc(CS(=O)(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)cs1
Show InChI InChI=1S/C18H14ClN3O5S3/c19-12-5-6-16(29(23,24)10-13-9-28-18(20)21-13)14(8-12)22-30(25,26)17-7-11-3-1-2-4-15(11)27-17/h1-9,22H,10H2,(H2,20,21)
PDB

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n/an/a 83n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327345
PNG
(US9663460, Example 151 | tert-butyl {4-[({2-[(1-be...)
Show SMILES CC(C)(C)OC(=O)Nc1cc(CS(=O)(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)cc[n+]1[O-]
Show InChI InChI=1S/C25H24ClN3O8S2/c1-25(2,3)37-24(30)27-22-12-16(10-11-29(22)31)15-38(32,33)21-9-8-18(26)14-19(21)28-39(34,35)23-13-17-6-4-5-7-20(17)36-23/h4-14,28H,15H2,1-3H3,(H,27,30)
PDB

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n/an/a 2.87E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327351
PNG
(N-{2-[(3-aminobenzyl)sulfonyl]-5-chlorophenyl}-1-b...)
Show SMILES Nc1cccc(CS(=O)(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C21H17ClN2O5S2/c22-16-8-9-20(30(25,26)13-14-4-3-6-17(23)10-14)18(12-16)24-31(27,28)21-11-15-5-1-2-7-19(15)29-21/h1-12,24H,13,23H2
PDB

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n/an/a 23n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327364
PNG
(N-(5-chloro-2-{[2-(1H-pyrazol-4-yl)ethyl]-sulfinyl...)
Show SMILES Clc1ccc(c(NS(=O)(=O)c2cc3ccccc3o2)c1)S(=O)CCc1cn[nH]c1
Show InChI InChI=1S/C19H16ClN3O4S2/c20-15-5-6-18(28(24)8-7-13-11-21-22-12-13)16(10-15)23-29(25,26)19-9-14-3-1-2-4-17(14)27-19/h1-6,9-12,23H,7-8H2,(H,21,22)
PDB

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n/an/a 1.06E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327367
PNG
(N-(5-chloro-2-{[2-(1H-pyrazol-4-yl)ethyl]thio}-phe...)
Show SMILES Clc1ccc(SCCc2cn[nH]c2)c(NS(=O)(=O)c2cc3ccccc3o2)c1
Show InChI InChI=1S/C19H16ClN3O3S2/c20-15-5-6-18(27-8-7-13-11-21-22-12-13)16(10-15)23-28(24,25)19-9-14-3-1-2-4-17(14)26-19/h1-6,9-12,23H,7-8H2,(H,21,22)
PDB

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n/an/a 412n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327370
PNG
(N-(5-chloro-2-{[2-(3,5-dimethyl-1H-pyrazol-4-yl)et...)
Show SMILES Cc1n[nH]c(C)c1CCS(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C21H20ClN3O4S2/c1-13-17(14(2)24-23-13)9-10-30(26)20-8-7-16(22)12-18(20)25-31(27,28)21-11-15-5-3-4-6-19(15)29-21/h3-8,11-12,25H,9-10H2,1-2H3,(H,23,24)
PDB

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UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 3.05E+3n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327372
PNG
(N-(5-chloro-2-{[(2-fluoropyridin-3-yl)methyl]-thio...)
Show SMILES Fc1ncccc1CSc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C20H14ClFN2O3S2/c21-15-7-8-18(28-12-14-5-3-9-23-20(14)22)16(11-15)24-29(25,26)19-10-13-4-1-2-6-17(13)27-19/h1-11,24H,12H2
PDB

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UniProtKB/SwissProt

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PC cid
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UniChem
US Patent
n/an/a 94n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327396
PNG
(N-{2-[(2-aminobenzyl)thio]-5-chlorophenyl}-1-benzo...)
Show SMILES Nc1ccccc1CSc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C21H17ClN2O3S2/c22-16-9-10-20(28-13-15-6-1-3-7-17(15)23)18(12-16)24-29(25,26)21-11-14-5-2-4-8-19(14)27-21/h1-12,24H,13,23H2
PDB

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UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 100n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327401
PNG
(N-{2-[(2-aminobenzyl)sulfonyl]-5-chlorophenyl}-1-b...)
Show SMILES Nc1ccccc1CS(=O)(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C21H17ClN2O5S2/c22-16-9-10-20(30(25,26)13-15-6-1-3-7-17(15)23)18(12-16)24-31(27,28)21-11-14-5-2-4-8-19(14)29-21/h1-12,24H,13,23H2
PDB

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UniChem
US Patent
n/an/a 129n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327404
PNG
(N-{2-[(3-aminobenzyl)sulfonyl]-5-chlorophenyl}-2,4...)
Show SMILES Nc1cccc(CS(=O)(=O)c2ccc(Cl)cc2NS(=O)(=O)c2ccc(F)cc2F)c1
Show InChI InChI=1S/C19H15ClF2N2O4S2/c20-13-4-6-19(29(25,26)11-12-2-1-3-15(23)8-12)17(9-13)24-30(27,28)18-7-5-14(21)10-16(18)22/h1-10,24H,11,23H2
PDB

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UniChem
US Patent
n/an/a 718n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM327405
PNG
(N-{2-[(3-aminobenzyl)sulfinyl]-5-chlorophenyl}-2,4...)
Show SMILES Nc1cccc(CS(=O)c2ccc(Cl)cc2NS(=O)(=O)c2ccc(F)cc2F)c1
Show InChI InChI=1S/C19H15ClF2N2O3S2/c20-13-4-6-18(28(25)11-12-2-1-3-15(23)8-12)17(9-13)24-29(26,27)19-7-5-14(21)10-16(19)22/h1-10,24H,11,23H2
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 443n/an/an/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...


US Patent US9663460 (2017)

More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%