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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327829 (2-((R)-4-((S)-(3-bromophenyl)(phenyl)methyl)-2-met...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.934 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327832 (2-((R)-2-methyl-4-((R)-phenyl(3-(trifluoromethyl)p...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327844 (2-((R)-4-(cyclopropyl(3-(trifluoromethyl)phenyl)me...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327827 ((R)-2-(4-benzhydryl-2-methylpiperazin-1-yl)acetic ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.51 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327833 ((S)-2-((R)-4-(bis(4-chlorophenyl)methyl)-3-methylp...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.14 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327842 (2-((R)-2-methyl-4-((R)-phenyl(4-(2-phenylethynyl)p...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327828 (2-((R)-4-((R)-(3-bromophenyl)(phenyl)methyl)-2-met...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.94 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327835 (2-((R)-2-methyl-4-((R)-phenyl(m-tolyl)methyl)piper...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.32 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327836 (2-((R)-2-methyl-4-((R)-phenyl(3-(thiophen-2-yl)phe...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327834 (US9663476, Compound 30 | [(R)-4-((R)-biphenyl-3-yl...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327841 (US9663476, Compound 49 | [(R)-2-methyl-4-[(R)-(4&#...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 17.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327838 (2-((R)-2-methyl-4-((R)-(3-(methylthio)phenyl)(phen...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 37.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327845 ((R)-2-(4-(bis(4-chlorophenyl)methyl)-2-methylpiper...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 41.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327826 ((R)-2-(4-(phenyl(3-(trifluoromethyl)phenyl)methyl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 79.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327826 ((R)-2-(4-(phenyl(3-(trifluoromethyl)phenyl)methyl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327839 (US9663476, Compound 48 | [(R)-2-methyl-4-[(R)-(3&#...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 217 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327840 ((R)-2-((R)-4-(bis(4-chlorophenyl)methyl)-2-methylp...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycine transporter 1 (Homo sapiens (Human)) | BDBM327843 (2-((R)-2-methyl-4-((R)-thiophen-2-yl(3-(trifluorom...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc US Patent | Assay Description This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor... | US Patent US9663476 (2017) BindingDB Entry DOI: 10.7270/Q2KK9DWS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
