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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329341 ((2R)—N-[4-(2-{[4-(azetidin-1-ylcarbonyl)-2-me...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329342 ((2R)-2-(4-fluorophenyl)-N-[4-(2-{[2-methoxy-4-(2-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329358 ((2R)-2-amino-2-(4-fluorophenyl)-N-[4-(2-{[4-(pyrro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329357 ((2R)-2-amino-N-{4-[2-({4-[(3-fluoroazetidin-1-yl)c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329344 ((2R)-2-amino-2-(4-fluorophenyl)-N-[4-(2-{[2-methox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329346 ((2R)-2-(4-fluorophenyl)-N-[4-(2-{[2-methoxy-4-(pyr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329348 ((2R)-2-(4-fluorophenyl)-N-{4-[2-({4-[(3-hydroxyaze...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329345 (4-{[6-(4-{[(2R)-2-(4-fluorophenyl)propanoyl]amino}...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329347 ((2R)—N-{4-[2-({4-[(3-fluoroazetidin-1-yl)carb...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329350 ((2S)-2-(4-fluorophenyl)-3-hydroxy-N-[4-(2-{[2-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329334 ((2R)-2-(4-fluorophenyl)-N-[4-(2-{[2-methoxy-4-(met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329352 ((2R)-2-amino-2-(4-fluorophenyl)-N-[4-(2-{[4-(methy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329343 ((−)-2-(4-fluorophenyl)-3-hydroxy-N-[4-(2-{[4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329353 ((2R)-2-amino-2-(4-fluorophenyl)-N-[4-(2-{[2-methox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329354 ((2R)-2-amino-N-{4-[2-({4-[(3-fluoroazetidin-1-yl)c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329356 ((2R)-2-amino-2-(4-fluorophenyl)-N-[4-(2-{[2-methox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329339 (4-{[6-(4-{[(2R)-2-(4-fluorophenyl)propanoyl]amino}...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329340 ((2R)—N-{4-[2-({4-[(3-fluoroazetidin-1-yl)carb...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329349 ((2R)-2-(4-fluorophenyl)-N-[4-(2-{[4-(pyrrolidin-1-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329335 ((2R)—N-[4-(2-{[2-ethoxy-4-(methylsulfonyl)phe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329336 ((2R)-2-(4-fluorophenyl)-N-[4-(2-{[4-(methylsulfony...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329351 ((2S)—N-{4-[2-({4-[(3-fluoroazetidin-1-yl)carb...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329337 (4-{[6-(4-{[(2R)-2-(4-fluorophenyl)propanoyl]amino}...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329338 (4-{[6-(4-{[2R)-2-(4-fluorophenyl)propanoyl]amino}p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329355 ((2R)-2-amino-N-[4-(2-{[4-(azetidin-1-ylcarbonyl)-2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329359 (US9663510, Example comparitive example 2) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329360 (US9663510, Example comparitive example disclosed i...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM329361 (US9663510, Example comparitive example 4) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9663510 (2017) BindingDB Entry DOI: 10.7270/Q2DV1N06 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
