Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330062![]() (2-(2-Chlorophenyl)-N-(5H-chromeno[3,4-c]pyridin-8-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.97 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330071![]() (2-(2-chloro-4- fluorophenyl)-N- (5H-chromeno[3,4- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.27 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330067![]() ((R)-2-amino-N- (5H-chromeno [3,4-c]pyridin-8- yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.43 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330156![]() (2-Phenyl-N-(9H-pyrido[3,4-b]indol-7-yl)acetamide |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330085![]() (N-(5H-chromeno[3,4- c]pyridin- 8-yl)-2-(4-fluoro-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 11.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330076![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- o-tolylacet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 16.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330070![]() ((R)-2-amino-N-(5H- chromeno[3,4- c]pyridin-8-yl)-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330155![]() (2-(3-Fluorophenyl)-N-(9H-pyrido[3,4-b]indol-7-yl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM263022![]() ((S)-2-amino-N-(5H-chromeno[3,4-c]pyridin-8-yl)-2-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 21.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330072![]() (2-(3-chlorophenyl)- N-(5H-chromeno [3,4-c]pyridin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 24.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330066![]() (2-(2-chlorophenyl)- N-(5H-chromeno [3,4-c]pyridin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 33.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330078![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (3,5-difluo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 37.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330087![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (4-fluoroph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 38.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330121![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-3- phenylpropa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 40.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330123![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- phenylaceta...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 43.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330154![]() (2-(3-Chlorophenyl)-N-(9H-pyrido[3,4-b]indol-7-yl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 46.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330153![]() (3-(3-Methoxyphenyl)-N-(9H-pyrido[3,4-b]indol-7-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 50.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330107![]() (N-(5H-chromeno[3,4- c]pyridin- 8-yl)-2-hydroxy-2- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 51.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330075![]() (N-(5H-chromeno [3,4-c]pyridin- 8-yl)-2-(2,4- dichl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 54.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330069![]() ((S)-2-amino-N-(5H- chromeno[3,4- c]pyridin-8-yl)-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330108![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (furan-2-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 56.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330133![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2,3- dihydro-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 58.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330088![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-3- ((4-(4-cyan...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 60.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330073![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2-m- tolylacet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 74.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330063![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-3- phenoxyprop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 82.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330077![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (3,5-dimeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330119![]() (N-(5H-chromeno[3,4- c]pyridin- 8-yl)-3-(4- hydroxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 111 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330065![]() ((R)-2-amino-N-(5H- chromeno[3,4- c]pyridin-8-yl)-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330150![]() (US9663529, Example III-4 | benzyl 5H- chromeno[3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 133 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330074![]() (2-(4-chlorophenyl)- N-(5H-chromeno [3,4-c]pyridin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330083![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2-(3- (trifluo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 159 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330082![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (2,6-dichlo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 161 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330137![]() (1-(5H-chromeno[3,4- c]pyridin- 8-yl)-3- phenethylu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 189 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330097![]() (N-(5H-chromeno [3,4-c]pyridin- 8-yl)-2-methyl-2- p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 204 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330095![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (pyridin-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 207 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330141![]() (1-(5H-chromeno[3,4- c]pyridin- 8-yl)-3-(2- fluorop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 233 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330144![]() (1-(3-chlorophenethyl)- 3-(5H- chromeno[3,4- c]pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 248 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330064![]() ((S)-2-amino-N-(5H- chromeno[3,4- c]pyridin-8-yl)-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 284 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330103![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (pyridin-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 287 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330086![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2-(4- (methylt...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 295 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330132![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (pyridin-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330098![]() (3-(4-chlorophenyl)- N-(5H-chromeno [3,4-c]pyridin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 323 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330129![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (3,4-dichlo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 362 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330094![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (pyridin-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 367 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330084![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (3-fluoro-5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 368 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330157![]() (2-(3-Cyanophenyl)-N-(9H-pyrido[3,4-b]indol-7-yl)ac...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 383 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330135![]() (N-(5H-Chromeno[3,4-c]pyridin-8-yl)indoline-1-carbo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 387 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330079![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (3,5-dimeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 393 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330096![]() (3-acetamido-N-(5H- chromeno[3,4-c] pyridin-8-yl) b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 434 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330128![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-3,3- diphenylp...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 471 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330092![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2-(4- methoxyp...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 497 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330101![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-4- sulfamoylbe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330136![]() (1-(2-chlorophenyl)- 3-(5H- chromeno[3,4- c]pyridin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 557 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330134![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-1H- benzo[d]im...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 619 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330117![]() (US9663529, Example I-56 | methyl 4-(5H- chromeno[3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 626 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330100![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (pyridin-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 644 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330093![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-4- phenylbutan...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 682 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330146![]() (1-(2-(benzo[d][1,3] dioxol-5-yl) ethyl)-3-(5H- chr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 685 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330099![]() (US9663529, Example I-38 | methyl 3-(5H- chromeno[3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 847 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330142![]() (1-(5H-chromeno[3,4- c]pyridin- 8-yl)-3-(2,2- diphe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330143![]() (1-(4-chlorophenethyl)- 3-(5H- chromeno[3,4- c]pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 971 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330109![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-3- (1H-imidazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 992 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330130![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (4-(trifluo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330148![]() (2-chlorophenyl 5H- chromeno[3,4-c] pyridin-8-ylcar...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330131![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2-(4- (4-oxoqu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330147![]() (Phenyl 5H-chromeno[3,4-c]pyridin-8-ylcarbamate | U...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330118![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-3- (4-methoxyp...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330112![]() (2-chloro-N-(5H- chromeno[3,4- c]pyridin-8- yl)benz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330126![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl) biphenyl-2- ca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330110![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (pyrazin-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330139![]() (1-(5H-chromeno[3,4- c]pyridin- 8-yl)-3- (pyridin-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330105![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl) thiazole- 4-ca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330140![]() (1-(5H-chromeno[3,4- c]pyridin- 8-yl)-3-(4- methoxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330081![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2-(4- (methyls...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330106![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl) pyrimidine-5- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330090![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-4- (methylsulf...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330104![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-3- (methylsulf...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330145![]() (1-(5H-chromeno[3,4- c]pyridin- 8-yl)-3-(5- methyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330124![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-4- (dimethylam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330138![]() (1-(3-chlorophenyl)-3- (5H- chromeno[3,4- c]pyridin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330080![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (3,4-dimeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330115![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-4- cyanobenzam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330127![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-3- methoxybenz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330102![]() (N-(5H-chromeno[3,4- c]pyridin- 8-yl)-1,2,3- thiadi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330149![]() (4-chlorophenyl 5H- chromeno[3,4-c] pyridin-8-ylcar...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330091![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl) pyrazine- 2-ca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330125![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-1- methyl-1H-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330116![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-4- methoxybenz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330089![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-4- fluorobenza...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330113![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-3- fluorobenza...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330151![]() (US9663529, Example III-5 | naphthalen-2-yl 5H- chr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330120![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- (1H-tetrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330152![]() (US9663529, Example III-6 | naphthalen-1-yl 5H- chr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330114![]() (3-chloro-N-(5H- chromeno[3,4- c]pyridin-8- yl)benz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330122![]() (N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- naphthamide...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM330111![]() (N-(5H-chromeno[3,4- c]pyridin- 8-yl)benzamide | US...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20... | US Patent US9663529 (2017) BindingDB Entry DOI: 10.7270/Q20P124H | |||||||||||
More data for this Ligand-Target Pair |