BindingDB logo
myBDB logout

Patent code US9676782

Compile Data Set for Download or QSAR

Found 342 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM193371
PNG
(2-(((4-(difluoromethoxy)phenyl)amino)methyl)-5-(4-...)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H17F3N4O2/c21-13-1-5-16(6-2-13)26-9-10-27-18(19(26)28)11-15(25-27)12-24-14-3-7-17(8-4-14)29-20(22)23/h1-8,11,20,24H,9-10,12H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 334n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM196331
PNG
(2-(((3,4-difluorophenyl)amino)methyl)-5-(4-fluorop...)
Show SMILES Fc1ccc(cc1)N1CCn2nc(CNc3ccc(F)c(F)c3)cc2C1=O
Show InChI InChI=1S/C19H15F3N4O/c20-12-1-4-15(5-2-12)25-7-8-26-18(19(25)27)10-14(24-26)11-23-13-3-6-16(21)17(22)9-13/h1-6,9-10,23H,7-8,11H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 462n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197278
PNG
(5-(4-fluorophenyl)-2-(((4-fluorophenyl)(methyl)ami...)
Show SMILES CN(Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C20H18F2N4O/c1-24(17-6-2-14(21)3-7-17)13-16-12-19-20(27)25(10-11-26(19)23-16)18-8-4-15(22)5-9-18/h2-9,12H,10-11,13H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 467n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM196596
PNG
(2-(((4-(difluoromethoxy)-3-fluorophenyl)amino)meth...)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccc(F)cc2)cc1F
Show InChI InChI=1S/C20H16F4N4O2/c21-12-1-4-15(5-2-12)27-7-8-28-17(19(27)29)10-14(26-28)11-25-13-3-6-18(16(22)9-13)30-20(23)24/h1-6,9-10,20,25H,7-8,11H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 489n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM191594
PNG
(2-(((3-(difluoromethoxy)phenyl)amino)methyl)-5-(4-...)
Show SMILES FC(F)Oc1cccc(NCc2cc3C(=O)N(CCn3n2)c2ccc(F)cc2)c1
Show InChI InChI=1S/C20H17F3N4O2/c21-13-4-6-16(7-5-13)26-8-9-27-18(19(26)28)11-15(25-27)12-24-14-2-1-3-17(10-14)29-20(22)23/h1-7,10-11,20,24H,8-9,12H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 505n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM196291
PNG
(2-(((2,5-difluorophenyl)amino)methyl)-5-(4-fluorop...)
Show SMILES Fc1ccc(cc1)N1CCn2nc(CNc3cc(F)ccc3F)cc2C1=O
Show InChI InChI=1S/C19H15F3N4O/c20-12-1-4-15(5-2-12)25-7-8-26-18(19(25)27)10-14(24-26)11-23-17-9-13(21)3-6-16(17)22/h1-6,9-10,23H,7-8,11H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 508n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197965
PNG
(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccc(F)cn2)c(F)c1
Show InChI InChI=1S/C19H15F4N5O2/c20-11-1-4-17(25-9-11)27-5-6-28-16(18(27)29)7-12(26-28)10-24-15-3-2-13(8-14(15)21)30-19(22)23/h1-4,7-9,19,24H,5-6,10H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 578n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197329
PNG
(5-(4-chlorophenyl)-2-(((4-methoxyphenyl)(methyl)am...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H21ClN4O2/c1-24(17-7-9-19(28-2)10-8-17)14-16-13-20-21(27)25(11-12-26(20)23-16)18-5-3-15(22)4-6-18/h3-10,13H,11-12,14H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 585n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM193379
PNG
(2-(((2,3-difluorophenyl)amino)methyl)-5-(4-fluorop...)
Show SMILES Fc1ccc(cc1)N1CCn2nc(CNc3cccc(F)c3F)cc2C1=O
Show InChI InChI=1S/C19H15F3N4O/c20-12-4-6-14(7-5-12)25-8-9-26-17(19(25)27)10-13(24-26)11-23-16-3-1-2-15(21)18(16)22/h1-7,10,23H,8-9,11H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 586n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197328
PNG
(US9676782, 95)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2cccc(F)c2)c(F)c1
Show InChI InChI=1S/C20H16F4N4O2/c21-12-2-1-3-14(8-12)27-6-7-28-18(19(27)29)9-13(26-28)11-25-17-5-4-15(10-16(17)22)30-20(23)24/h1-5,8-10,20,25H,6-7,11H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 588n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197324
PNG
(2-(((4-bromophenyl)(methyl)amino)methyl)-5-(4-fluo...)
Show SMILES CN(Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1)c1ccc(Br)cc1
Show InChI InChI=1S/C20H18BrFN4O/c1-24(17-6-2-14(21)3-7-17)13-16-12-19-20(27)25(10-11-26(19)23-16)18-8-4-15(22)5-9-18/h2-9,12H,10-11,13H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 592n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197196
PNG
(5-(4-fluorophenyl)-2-(((3-fluorophenyl)(methyl)ami...)
Show SMILES CN(Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1)c1cccc(F)c1
Show InChI InChI=1S/C20H18F2N4O/c1-24(18-4-2-3-15(22)11-18)13-16-12-19-20(27)25(9-10-26(19)23-16)17-7-5-14(21)6-8-17/h2-8,11-12H,9-10,13H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 594n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM198682
PNG
(2-(((5-chloropyridin-2-yl)amino)methyl)-5-(4-fluor...)
Show SMILES Fc1ccc(cc1)N1CCn2nc(CNc3ccc(Cl)cn3)cc2C1=O
Show InChI InChI=1S/C18H15ClFN5O/c19-12-1-6-17(21-10-12)22-11-14-9-16-18(26)24(7-8-25(16)23-14)15-4-2-13(20)3-5-15/h1-6,9-10H,7-8,11H2,(H,21,22)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 602n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197950
PNG
(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Show SMILES Cc1nc(cs1)N1CCn2nc(CNc3ccc(OC(F)F)cc3F)cc2C1=O
Show InChI InChI=1S/C18H16F3N5O2S/c1-10-23-16(9-29-10)25-4-5-26-15(17(25)27)6-11(24-26)8-22-14-3-2-12(7-13(14)19)28-18(20)21/h2-3,6-7,9,18,22H,4-5,8H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 624n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197327
PNG
(2-(((3,5-difluorophenyl)(methyl)amino)methyl)-5-(4...)
Show SMILES CN(Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1)c1cc(F)cc(F)c1
Show InChI InChI=1S/C20H17F3N4O/c1-25(18-9-14(22)8-15(23)10-18)12-16-11-19-20(28)26(6-7-27(19)24-16)17-4-2-13(21)3-5-17/h2-5,8-11H,6-7,12H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 660n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197331
PNG
(5-(3-chlorophenyl)-2-(((4-methoxyphenyl)(methyl)am...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1cccc(Cl)c1
Show InChI InChI=1S/C21H21ClN4O2/c1-24(17-6-8-19(28-2)9-7-17)14-16-13-20-21(27)25(10-11-26(20)23-16)18-5-3-4-15(22)12-18/h3-9,12-13H,10-11,14H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 668n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197332
PNG
(2-(((4-methoxyphenyl)(methyl)amino)methyl)-5-(p-to...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1ccc(C)cc1
Show InChI InChI=1S/C22H24N4O2/c1-16-4-6-19(7-5-16)25-12-13-26-21(22(25)27)14-17(23-26)15-24(2)18-8-10-20(28-3)11-9-18/h4-11,14H,12-13,15H2,1-3H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 675n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197956
PNG
(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccc(F)cc2F)c(F)c1
Show InChI InChI=1S/C20H15F5N4O2/c21-11-1-4-17(15(23)7-11)28-5-6-29-18(19(28)30)8-12(27-29)10-26-16-3-2-13(9-14(16)22)31-20(24)25/h1-4,7-9,20,26H,5-6,10H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 706n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM193371
PNG
(2-(((4-(difluoromethoxy)phenyl)amino)methyl)-5-(4-...)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H17F3N4O2/c21-13-1-5-16(6-2-13)26-9-10-27-18(19(26)28)11-15(25-27)12-24-14-3-7-17(8-4-14)29-20(22)23/h1-8,11,20,24H,9-10,12H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 709n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM196309
PNG
(2-(((3,5-difluorophenyl)amino)methyl)-5-(4-fluorop...)
Show SMILES Fc1ccc(cc1)N1CCn2nc(CNc3cc(F)cc(F)c3)cc2C1=O
Show InChI InChI=1S/C19H15F3N4O/c20-12-1-3-17(4-2-12)25-5-6-26-18(19(25)27)10-16(24-26)11-23-15-8-13(21)7-14(22)9-15/h1-4,7-10,23H,5-6,11H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 738n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM196750
PNG
((r)-2-(((2,4-difluorophenyl)amino)methyl)-5-(4-flu...)
Show SMILES C[C@@H]1CN(C(=O)c2cc(CNc3ccc(F)cc3F)nn12)c1ccc(F)cc1
Show InChI InChI=1S/C20H17F3N4O/c1-12-11-26(16-5-2-13(21)3-6-16)20(28)19-9-15(25-27(12)19)10-24-18-7-4-14(22)8-17(18)23/h2-9,12,24H,10-11H2,1H3/t12-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 771n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM198263
PNG
(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccccc2F)c(F)c1
Show InChI InChI=1S/C20H16F4N4O2/c21-14-3-1-2-4-17(14)27-7-8-28-18(19(27)29)9-12(26-28)11-25-16-6-5-13(10-15(16)22)30-20(23)24/h1-6,9-10,20,25H,7-8,11H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 772n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197333
PNG
(5-(2-chlorophenyl)-2-(((4-methoxyphenyl)(methyl)am...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1ccccc1Cl
Show InChI InChI=1S/C21H21ClN4O2/c1-24(16-7-9-17(28-2)10-8-16)14-15-13-20-21(27)25(11-12-26(20)23-15)19-6-4-3-5-18(19)22/h3-10,13H,11-12,14H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 777n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197334
PNG
(5-(3-fluorophenyl)-2-(((4-methoxyphenyl)(methyl)am...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1cccc(F)c1
Show InChI InChI=1S/C21H21FN4O2/c1-24(17-6-8-19(28-2)9-7-17)14-16-13-20-21(27)25(10-11-26(20)23-16)18-5-3-4-15(22)12-18/h3-9,12-13H,10-11,14H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 783n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM196567
PNG
(2-(((2-fluoro-4-methylphenyl)amino)methyl)-5-(4-fl...)
Show SMILES Cc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccc(F)cc2)c(F)c1
Show InChI InChI=1S/C20H18F2N4O/c1-13-2-7-18(17(22)10-13)23-12-15-11-19-20(27)25(8-9-26(19)24-15)16-5-3-14(21)4-6-16/h2-7,10-11,23H,8-9,12H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 799n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197963
PNG
(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccc(F)c(F)c2)c(F)c1
Show InChI InChI=1S/C20H15F5N4O2/c21-14-3-1-12(8-15(14)22)28-5-6-29-18(19(28)30)7-11(27-29)10-26-17-4-2-13(9-16(17)23)31-20(24)25/h1-4,7-9,20,26H,5-6,10H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 800n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197335
PNG
(2-(((4-methoxyphenyl)(methyl)amino)methyl)-5-(2,4,...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1c(F)cc(F)cc1F
Show InChI InChI=1S/C21H19F3N4O2/c1-26(15-3-5-16(30-2)6-4-15)12-14-11-19-21(29)27(7-8-28(19)25-14)20-17(23)9-13(22)10-18(20)24/h3-6,9-11H,7-8,12H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 801n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197231
PNG
(2-(((3-chlorophenyl)(methyl)amino)methyl)-5-(4-flu...)
Show SMILES CN(Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1)c1cccc(Cl)c1
Show InChI InChI=1S/C20H18ClFN4O/c1-24(18-4-2-3-14(21)11-18)13-16-12-19-20(27)25(9-10-26(19)23-16)17-7-5-15(22)6-8-17/h2-8,11-12H,9-10,13H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 805n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197338
PNG
(2-(((4-methoxyphenyl)(methyl)amino)methyl)-5-(m-to...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1cccc(C)c1
Show InChI InChI=1S/C22H24N4O2/c1-16-5-4-6-19(13-16)25-11-12-26-21(22(25)27)14-17(23-26)15-24(2)18-7-9-20(28-3)10-8-18/h4-10,13-14H,11-12,15H2,1-3H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 805n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197945
PNG
(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Show SMILES CN(Cc1cc2C(=O)N(CCn2n1)c1cc(Cl)ccn1)c1ccc(OC(F)F)cc1
Show InChI InChI=1S/C20H18ClF2N5O2/c1-26(15-2-4-16(5-3-15)30-20(22)23)12-14-11-17-19(29)27(8-9-28(17)25-14)18-10-13(21)6-7-24-18/h2-7,10-11,20H,8-9,12H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 821n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM196552
PNG
(2-(((4-chloro-2-fluorophenyl)amino)methyl)-5-(4-fl...)
Show SMILES Fc1ccc(cc1)N1CCn2nc(CNc3ccc(Cl)cc3F)cc2C1=O
Show InChI InChI=1S/C19H15ClF2N4O/c20-12-1-6-17(16(22)9-12)23-11-14-10-18-19(27)25(7-8-26(18)24-14)15-4-2-13(21)3-5-15/h1-6,9-10,23H,7-8,11H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 856n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197339
PNG
(5-(3,5-difluorophenyl)-2-(((4-methoxyphenyl)(methy...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1cc(F)cc(F)c1
Show InChI InChI=1S/C21H20F2N4O2/c1-25(17-3-5-19(29-2)6-4-17)13-16-12-20-21(28)26(7-8-27(20)24-16)18-10-14(22)9-15(23)11-18/h3-6,9-12H,7-8,13H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 856n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197957
PNG
(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Show SMILES COc1cccc(c1)N1CCn2nc(CNc3ccc(OC(F)F)cc3F)cc2C1=O
Show InChI InChI=1S/C21H19F3N4O3/c1-30-15-4-2-3-14(10-15)27-7-8-28-19(20(27)29)9-13(26-28)12-25-18-6-5-16(11-17(18)22)31-21(23)24/h2-6,9-11,21,25H,7-8,12H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 863n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM196608
PNG
((r)-5-(4-fluorophenyl)-2-(((2-fluorophenyl)amino)m...)
Show SMILES C[C@@H]1CN(C(=O)c2cc(CNc3ccccc3F)nn12)c1ccc(F)cc1
Show InChI InChI=1S/C20H18F2N4O/c1-13-12-25(16-8-6-14(21)7-9-16)20(27)19-10-15(24-26(13)19)11-23-18-5-3-2-4-17(18)22/h2-10,13,23H,11-12H2,1H3/t13-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 871n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197346
PNG
(5-(2-fluorophenyl)-2-(((4-methoxyphenyl)(methyl)am...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1ccccc1F
Show InChI InChI=1S/C21H21FN4O2/c1-24(16-7-9-17(28-2)10-8-16)14-15-13-20-21(27)25(11-12-26(20)23-15)19-6-4-3-5-18(19)22/h3-10,13H,11-12,14H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 871n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM196832
PNG
(5-(4-fluorophenyl)-2-(((2-fluorophenyl)(methyl)ami...)
Show SMILES CN(Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1)c1ccccc1F
Show InChI InChI=1S/C20H18F2N4O/c1-24(18-5-3-2-4-17(18)22)13-15-12-19-20(27)25(10-11-26(19)23-15)16-8-6-14(21)7-9-16/h2-9,12H,10-11,13H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 876n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197323
PNG
(2-(((4-chlorophenyl)(methyl)amino)methyl)-5-(4-flu...)
Show SMILES CN(Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H18ClFN4O/c1-24(17-6-2-14(21)3-7-17)13-16-12-19-20(27)25(10-11-26(19)23-16)18-8-4-15(22)5-9-18/h2-9,12H,10-11,13H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 885n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM193377
PNG
(2-(4-(((5-(4-fluorophenyl)-4-oxo-4,5,6,7-tetrahydr...)
Show SMILES Fc1ccc(cc1)N1CCn2nc(CNc3ccc(cc3)C#C)cc2C1=O
Show InChI InChI=1S/C21H17FN4O/c1-2-15-3-7-17(8-4-15)23-14-18-13-20-21(27)25(11-12-26(20)24-18)19-9-5-16(22)6-10-19/h1,3-10,13,23H,11-12,14H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 890n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197636
PNG
(5-(5-chloropyridin-2-yl)-2-(((4-methoxyphenyl)(met...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1ccc(Cl)cn1
Show InChI InChI=1S/C20H20ClN5O2/c1-24(16-4-6-17(28-2)7-5-16)13-15-11-18-20(27)25(9-10-26(18)23-15)19-8-3-14(21)12-22-19/h3-8,11-12H,9-10,13H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 917n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197969
PNG
(5-(5-chloropyridin-2-yl)-2-(((4-(difluoromethoxy)-...)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccc(Cl)cn2)c(F)c1
Show InChI InChI=1S/C19H15ClF3N5O2/c20-11-1-4-17(25-9-11)27-5-6-28-16(18(27)29)7-12(26-28)10-24-15-3-2-13(8-14(15)21)30-19(22)23/h1-4,7-9,19,24H,5-6,10H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 930n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197972
PNG
(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccccn2)c(F)c1
Show InChI InChI=1S/C19H16F3N5O2/c20-14-10-13(29-19(21)22)4-5-15(14)24-11-12-9-16-18(28)26(7-8-27(16)25-12)17-3-1-2-6-23-17/h1-6,9-10,19,24H,7-8,11H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 943n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM191566
PNG
(5-(4-fluorophenyl)-2-(((2-fluorophenyl)amino)methy...)
Show SMILES Fc1ccc(cc1)N1CCn2nc(CNc3ccccc3F)cc2C1=O
Show InChI InChI=1S/C19H16F2N4O/c20-13-5-7-15(8-6-13)24-9-10-25-18(19(24)26)11-14(23-25)12-22-17-4-2-1-3-16(17)21/h1-8,11,22H,9-10,12H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 944n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197958
PNG
(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Show SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ncccc2F)c(F)c1
Show InChI InChI=1S/C19H15F4N5O2/c20-13-2-1-5-24-17(13)27-6-7-28-16(18(27)29)8-11(26-28)10-25-15-4-3-12(9-14(15)21)30-19(22)23/h1-5,8-9,19,25H,6-7,10H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 950n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197325
PNG
(5-(4-fluorophenyl)-2-(((4-methoxyphenyl)(methyl)am...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1
Show InChI InChI=1S/C21H21FN4O2/c1-24(17-7-9-19(28-2)10-8-17)14-16-13-20-21(27)25(11-12-26(20)23-16)18-5-3-15(22)4-6-18/h3-10,13H,11-12,14H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 986n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197347
PNG
(5-(2,5-difluorophenyl)-2-(((4-methoxyphenyl)(methy...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1c(F)cccc1F
Show InChI InChI=1S/C21H20F2N4O2/c1-25(15-6-8-16(29-2)9-7-15)13-14-12-19-21(28)26(10-11-27(19)24-14)20-17(22)4-3-5-18(20)23/h3-9,12H,10-11,13H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.02E+3n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197243
PNG
(5-(4-fluorophenyl)-2-(((3-methoxyphenyl)(methyl)am...)
Show SMILES COc1cccc(c1)N(C)Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1
Show InChI InChI=1S/C21H21FN4O2/c1-24(18-4-3-5-19(13-18)28-2)14-16-12-20-21(27)25(10-11-26(20)23-16)17-8-6-15(22)7-9-17/h3-9,12-13H,10-11,14H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.02E+3n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197369
PNG
(5-(2,3-difluorophenyl)-2-(((4-methoxyphenyl)(methy...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1cccc(F)c1F
Show InChI InChI=1S/C21H20F2N4O2/c1-25(15-6-8-16(29-2)9-7-15)13-14-12-19-21(28)26(10-11-27(19)24-14)18-5-3-4-17(22)20(18)23/h3-9,12H,10-11,13H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.03E+3n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM197635
PNG
(5-(4-(difluoromethoxy)phenyl)-2-(((4-methoxyphenyl...)
Show SMILES COc1ccc(cc1)N(C)Cc1cc2C(=O)N(CCn2n1)c1ccc(OC(F)F)cc1
Show InChI InChI=1S/C22H22F2N4O3/c1-26(16-3-7-18(30-2)8-4-16)14-15-13-20-21(29)27(11-12-28(20)25-15)17-5-9-19(10-6-17)31-22(23)24/h3-10,13,22H,11-12,14H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.03E+3n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM191575
PNG
(5-(4-fluorophenyl)-2-(((3-fluorophenyl)amino)methy...)
Show SMILES Fc1ccc(cc1)N1CCn2nc(CNc3cccc(F)c3)cc2C1=O
Show InChI InChI=1S/C19H16F2N4O/c20-13-4-6-17(7-5-13)24-8-9-25-18(19(24)26)11-16(23-25)12-22-15-3-1-2-14(21)10-15/h1-7,10-11,22H,8-9,12H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.04E+3n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3 (mGlu3)


(Rattus norvegicus (Rat))
BDBM196363
PNG
(2-(((2,6-difluorophenyl)amino)methyl)-5-(4-fluorop...)
Show SMILES Fc1ccc(cc1)N1CCn2nc(CNc3c(F)cccc3F)cc2C1=O
Show InChI InChI=1S/C19H15F3N4O/c20-12-4-6-14(7-5-12)25-8-9-26-17(19(25)27)10-13(24-26)11-23-18-15(21)2-1-3-16(18)22/h1-7,10,23H,8-9,11H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.05E+3n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...


Citation and Details
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 342 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%