BindingDB logo
myBDB logout

Patent code US9682967

Compile Data Set for Download or QSAR
Found 50 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neurotensin receptor 3


(Homo sapiens)
BDBM50445041
PNG
(CHEMBL3098768 | US9682967, 46)
Show SMILES OC(=O)c1cc(ccc1C(=O)Nc1ccc2CCCCc2n1)C(F)(F)F
Show InChI InChI=1S/C18H15F3N2O3/c19-18(20,21)11-6-7-12(13(9-11)17(25)26)16(24)23-15-8-5-10-3-1-2-4-14(10)22-15/h5-9H,1-4H2,(H,25,26)(H,22,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
84n/a 88n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445042
PNG
(CHEMBL3098767 | US9682967, 7)
Show SMILES Cc1ccc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)nc1C
Show InChI InChI=1S/C16H13F3N2O3/c1-8-3-6-13(20-9(8)2)21-14(22)11-5-4-10(16(17,18)19)7-12(11)15(23)24/h3-7H,1-2H3,(H,23,24)(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
162n/a 170n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159232
PNG
(US9682967, 45)
Show SMILES Cc1cnc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)nc1C
Show InChI InChI=1S/C15H12F3N3O3/c1-7-6-19-14(20-8(7)2)21-12(22)10-4-3-9(15(16,17)18)5-11(10)13(23)24/h3-6H,1-2H3,(H,23,24)(H,19,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
190n/a 200n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Sortilin


(Mouse)
BDBM50445054
PNG
(CHEMBL3098745 | US9682967, 1)
Show SMILES Cc1cccc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)n1
Show InChI InChI=1S/C15H11F3N2O3/c1-8-3-2-4-12(19-8)20-13(21)10-6-5-9(15(16,17)18)7-11(10)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
US Patent
210n/a 220n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159140
PNG
(US9682967, 18)
Show SMILES Cc1ncc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)nc1C
Show InChI InChI=1S/C15H12F3N3O3/c1-7-8(2)20-12(6-19-7)21-13(22)10-4-3-9(15(16,17)18)5-11(10)14(23)24/h3-6H,1-2H3,(H,23,24)(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
229n/a 240n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159226
PNG
(US9682967, 44)
Show SMILES Cc1nccc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)n1
Show InChI InChI=1S/C14H10F3N3O3/c1-7-18-5-4-11(19-7)20-12(21)9-3-2-8(14(15,16)17)6-10(9)13(22)23/h2-6H,1H3,(H,22,23)(H,18,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
286n/a 300n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159139
PNG
(US9682967, 17)
Show SMILES Cc1ccnc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)n1
Show InChI InChI=1S/C14H10F3N3O3/c1-7-4-5-18-13(19-7)20-11(21)9-3-2-8(14(15,16)17)6-10(9)12(22)23/h2-6H,1H3,(H,22,23)(H,18,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
343n/a 360n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159138
PNG
(US9682967, 16)
Show SMILES OC(=O)c1cc(ccc1C(=O)Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H7ClF6N2O3/c16-10-4-7(15(20,21)22)5-23-11(10)24-12(25)8-2-1-6(14(17,18)19)3-9(8)13(26)27/h1-5H,(H,26,27)(H,23,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
343n/a 360n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445054
PNG
(CHEMBL3098745 | US9682967, 1)
Show SMILES Cc1cccc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)n1
Show InChI InChI=1S/C15H11F3N2O3/c1-8-3-2-4-12(19-8)20-13(21)10-6-5-9(15(16,17)18)7-11(10)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
US Patent
429n/a 450n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neurotensin receptor 3


(Homo sapiens)
BDBM159123
PNG
(US9682967, 11)
Show SMILES Cc1ccc(NC(=O)c2cc(Cl)c(Cl)cc2C(O)=O)nc1C
Show InChI InChI=1S/C15H12Cl2N2O3/c1-7-3-4-13(18-8(7)2)19-14(20)9-5-11(16)12(17)6-10(9)15(21)22/h3-6H,1-2H3,(H,21,22)(H,18,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
457n/a 480n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159129
PNG
(US9682967, 13)
Show SMILES Cc1nccc(NC(=O)c2cc(Cl)c(Cl)cc2C(O)=O)n1
Show InChI InChI=1S/C13H9Cl2N3O3/c1-6-16-3-2-11(17-6)18-12(19)7-4-9(14)10(15)5-8(7)13(20)21/h2-5H,1H3,(H,20,21)(H,16,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
457n/a 480n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445044
PNG
(CHEMBL3098765 | US9682967, 34)
Show SMILES Cc1nccc(NC(=O)c2ccc(Br)cc2C(O)=O)n1
Show InChI InChI=1S/C13H10BrN3O3/c1-7-15-5-4-11(16-7)17-12(18)9-3-2-8(14)6-10(9)13(19)20/h2-6H,1H3,(H,19,20)(H,15,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
US Patent
467n/a 490n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159154
PNG
(US9682967, 23)
Show SMILES Cc1ccc(NC(=O)c2ccc(Br)cc2C(O)=O)nc1C
Show InChI InChI=1S/C15H13BrN2O3/c1-8-3-6-13(17-9(8)2)18-14(19)11-5-4-10(16)7-12(11)15(20)21/h3-7H,1-2H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
543n/a 570n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159285
PNG
(US9682967, 50)
Show SMILES Cc1nccc(NC(=O)c2cc(c(cc2C(O)=O)C(F)(F)F)C(F)(F)F)n1
Show InChI InChI=1S/C15H9F6N3O3/c1-6-22-3-2-11(23-6)24-12(25)7-4-9(14(16,17)18)10(15(19,20)21)5-8(7)13(26)27/h2-5H,1H3,(H,26,27)(H,22,23,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
599n/a 620n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159286
PNG
(US9682967, 51)
Show SMILES Cc1cc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)cc(C)n1
Show InChI InChI=1S/C16H13F3N2O3/c1-8-5-11(6-9(2)20-8)21-14(22)12-4-3-10(16(17,18)19)7-13(12)15(23)24/h3-7H,1-2H3,(H,23,24)(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
614n/a 640n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159121
PNG
(US9682967, 9)
Show SMILES Cc1cc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)ccn1
Show InChI InChI=1S/C15H11F3N2O3/c1-8-6-10(4-5-19-8)20-13(21)11-3-2-9(15(16,17)18)7-12(11)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
667n/a 700n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159189
PNG
(US9682967, 36)
Show SMILES COc1cc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)ccn1
Show InChI InChI=1S/C15H11F3N2O4/c1-24-12-7-9(4-5-19-12)20-13(21)10-3-2-8(15(16,17)18)6-11(10)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
714n/a 750n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159272
PNG
(US9682967, 48)
Show SMILES OC(=O)c1cc(c(cc1C(=O)Nc1ccc2CCCCc2n1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H14F6N2O3/c20-18(21,22)12-7-10(11(17(29)30)8-13(12)19(23,24)25)16(28)27-15-6-5-9-3-1-2-4-14(9)26-15/h5-8H,1-4H2,(H,29,30)(H,26,27,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
721n/a 760n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159273
PNG
(US9682967, 49)
Show SMILES Cc1ccc(NC(=O)c2cc(c(cc2C(O)=O)C(F)(F)F)C(F)(F)F)nc1C
Show InChI InChI=1S/C17H12F6N2O3/c1-7-3-4-13(24-8(7)2)25-14(26)9-5-11(16(18,19)20)12(17(21,22)23)6-10(9)15(27)28/h3-6H,1-2H3,(H,27,28)(H,24,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
734n/a 750n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445051
PNG
(CHEMBL3098752 | US9682967, 5)
Show SMILES Cc1cccc(NC(=O)c2cc(Cl)c(Cl)cc2C(O)=O)n1
Show InChI InChI=1S/C14H10Cl2N2O3/c1-7-3-2-4-12(17-7)18-13(19)8-5-10(15)11(16)6-9(8)14(20)21/h2-6H,1H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
790n/a 830n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159181
PNG
(US9682967, 33)
Show SMILES Cc1cc(C)nc(NC(=O)c2ccc(Br)cc2C(O)=O)c1
Show InChI InChI=1S/C15H13BrN2O3/c1-8-5-9(2)17-13(6-8)18-14(19)11-4-3-10(16)7-12(11)15(20)21/h3-7H,1-2H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
924n/a 970n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159146
PNG
(US9682967, 20)
Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1ccc(Cl)cn1
Show InChI InChI=1S/C13H8BrClN2O3/c14-7-1-3-9(10(5-7)13(19)20)12(18)17-11-4-2-8(15)6-16-11/h1-6H,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
943n/a 990n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159117
PNG
(US9682967, 8)
Show SMILES Cc1ccnc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)c1
Show InChI InChI=1S/C15H11F3N2O3/c1-8-4-5-19-12(6-8)20-13(21)10-3-2-9(15(16,17)18)7-11(10)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
952n/a 1.00E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445055
PNG
(CHEMBL3098744 | US9682967, 43)
Show SMILES CC(C)c1ccc(C(=O)Nc2cccc(C)n2)c(c1)C(O)=O
Show InChI InChI=1S/C17H18N2O3/c1-10(2)12-7-8-13(14(9-12)17(21)22)16(20)19-15-6-4-5-11(3)18-15/h4-10H,1-3H3,(H,21,22)(H,18,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
1.05E+3n/a 1.10E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445058
PNG
(CHEMBL3098741 | US9682967, 2)
Show SMILES Cc1cccc(NC(=O)c2ccc(Br)cc2C(O)=O)n1
Show InChI InChI=1S/C14H11BrN2O3/c1-8-3-2-4-12(16-8)17-13(18)10-6-5-9(15)7-11(10)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
1.14E+3n/a 1.20E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159271
PNG
(US9682967, 47)
Show SMILES Cc1cccc(NC(=O)c2cc(c(cc2C(O)=O)C(F)(F)F)C(F)(F)F)n1
Show InChI InChI=1S/C16H10F6N2O3/c1-7-3-2-4-12(23-7)24-13(25)8-5-10(15(17,18)19)11(16(20,21)22)6-9(8)14(26)27/h2-6H,1H3,(H,26,27)(H,23,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
1.14E+3n/a 1.20E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159169
PNG
(US9682967, 29)
Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1ccc2ccccc2n1
Show InChI InChI=1S/C17H11BrN2O3/c18-11-6-7-12(13(9-11)17(22)23)16(21)20-15-8-5-10-3-1-2-4-14(10)19-15/h1-9H,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
1.24E+3n/a 1.30E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445043
PNG
(CHEMBL3098766 | US9682967, 37)
Show SMILES COc1cccc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)n1
Show InChI InChI=1S/C15H11F3N2O4/c1-24-12-4-2-3-11(19-12)20-13(21)9-6-5-8(15(16,17)18)7-10(9)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
US Patent
1.24E+3n/a 1.30E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445057
PNG
(CHEMBL3098742 | US9682967, 4)
Show SMILES Cc1cccc(NC(=O)c2ccc(Cl)cc2C(O)=O)n1
Show InChI InChI=1S/C14H11ClN2O3/c1-8-3-2-4-12(16-8)17-13(18)10-6-5-9(15)7-11(10)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
1.33E+3n/a 1.40E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159199
PNG
(US9682967, 38)
Show SMILES OC(=O)c1cc(ccc1C(=O)NCc1ccccn1)C(F)(F)F
Show InChI InChI=1S/C15H11F3N2O3/c16-15(17,18)9-4-5-11(12(7-9)14(22)23)13(21)20-8-10-3-1-2-6-19-10/h1-7H,8H2,(H,20,21)(H,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
1.52E+3n/a 1.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445047
PNG
(CHEMBL3098760 | US9682967, 22)
Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1cccc(Cl)n1
Show InChI InChI=1S/C13H8BrClN2O3/c14-7-4-5-8(9(6-7)13(19)20)12(18)17-11-3-1-2-10(15)16-11/h1-6H,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
1.52E+3n/a 1.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159143
PNG
(US9682967, 19)
Show SMILES Cc1ccc(NC(=O)c2ccc(Br)cc2C(O)=O)nc1
Show InChI InChI=1S/C14H11BrN2O3/c1-8-2-5-12(16-7-8)17-13(18)10-4-3-9(15)6-11(10)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
1.62E+3n/a 1.70E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159126
PNG
(US9682967, 12)
Show SMILES Cc1cc(NC(=O)c2cc(Cl)c(Cl)cc2C(O)=O)ccn1
Show InChI InChI=1S/C14H10Cl2N2O3/c1-7-4-8(2-3-17-7)18-13(19)9-5-11(15)12(16)6-10(9)14(20)21/h2-6H,1H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
1.71E+3n/a 1.80E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445045
PNG
(CHEMBL3098764 | US9682967, 25)
Show SMILES Cc1cc(NC(=O)c2ccc(Br)cc2C(O)=O)ccn1
Show InChI InChI=1S/C14H11BrN2O3/c1-8-6-10(4-5-16-8)17-13(18)11-3-2-9(15)7-12(11)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
US Patent
1.71E+3n/a 1.80E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159188
PNG
(US9682967, 35)
Show SMILES Cc1cc(NC(=O)c2ccc(Br)cc2C(O)=O)ncn1
Show InChI InChI=1S/C13H10BrN3O3/c1-7-4-11(16-6-15-7)17-12(18)9-3-2-8(14)5-10(9)13(19)20/h2-6H,1H3,(H,19,20)(H,15,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
1.91E+3n/a 2.00E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159172
PNG
(US9682967, 30)
Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1ccc(Cl)c(Cl)n1
Show InChI InChI=1S/C13H7BrCl2N2O3/c14-6-1-2-7(8(5-6)13(20)21)12(19)18-10-4-3-9(15)11(16)17-10/h1-5H,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
2.00E+3n/a 2.10E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159122
PNG
(US9682967, 10)
Show SMILES Cc1ccnc(NC(=O)c2cc(Cl)c(Cl)cc2C(O)=O)c1
Show InChI InChI=1S/C14H10Cl2N2O3/c1-7-2-3-17-12(4-7)18-13(19)8-5-10(15)11(16)6-9(8)14(20)21/h2-6H,1H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
2.10E+3n/a 2.20E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445046
PNG
(CHEMBL3098761 | US9682967, 24)
Show SMILES Cc1ccnc(NC(=O)c2ccc(Br)cc2C(O)=O)c1
Show InChI InChI=1S/C14H11BrN2O3/c1-8-4-5-16-12(6-8)17-13(18)10-3-2-9(15)7-11(10)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
2.29E+3n/a 2.40E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159178
PNG
(US9682967, 32)
Show SMILES Cc1ccc(NC(=O)c2ccc(Br)cc2C(O)=O)nn1
Show InChI InChI=1S/C13H10BrN3O3/c1-7-2-5-11(17-16-7)15-12(18)9-4-3-8(14)6-10(9)13(19)20/h2-6H,1H3,(H,19,20)(H,15,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
3.05E+3n/a 3.20E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445050
PNG
(CHEMBL3098753 | US9682967, 15)
Show SMILES Cc1cccc(NC(=O)c2cc(C)c(C)cc2C(O)=O)n1
Show InChI InChI=1S/C16H16N2O3/c1-9-7-12(13(16(20)21)8-10(9)2)15(19)18-14-6-4-5-11(3)17-14/h4-8H,1-3H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
3.24E+3n/a 3.40E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159210
PNG
(US9682967, 41)
Show SMILES CCCc1ccc(C(=O)Nc2cccc(C)n2)c(c1)C(O)=O
Show InChI InChI=1S/C17H18N2O3/c1-3-5-12-8-9-13(14(10-12)17(21)22)16(20)19-15-7-4-6-11(2)18-15/h4,6-10H,3,5H2,1-2H3,(H,21,22)(H,18,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
3.43E+3n/a 3.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159166
PNG
(US9682967, 28)
Show SMILES Cc1csc(NC(=O)c2ccc(Br)cc2C(O)=O)n1
Show InChI InChI=1S/C12H9BrN2O3S/c1-6-5-19-12(14-6)15-10(16)8-3-2-7(13)4-9(8)11(17)18/h2-5H,1H3,(H,17,18)(H,14,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
3.43E+3n/a 3.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445048
PNG
(CHEMBL3098759 | US9682967, 21)
Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1ccccn1
Show InChI InChI=1S/C13H9BrN2O3/c14-8-4-5-9(10(7-8)13(18)19)12(17)16-11-3-1-2-6-15-11/h1-7H,(H,18,19)(H,15,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
3.43E+3n/a 3.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159134
PNG
(US9682967, 14)
Show SMILES Cc1cccc(NC(=O)c2ccc(Cl)c(F)c2C(O)=O)n1
Show InChI InChI=1S/C14H10ClFN2O3/c1-7-3-2-4-10(17-7)18-13(19)8-5-6-9(15)12(16)11(8)14(20)21/h2-6H,1H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
4.00E+3n/a 4.20E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159206
PNG
(US9682967, 40)
Show SMILES OC(=O)c1cc(ccc1C(=O)NCc1cccnc1)C(F)(F)F
Show InChI InChI=1S/C15H11F3N2O3/c16-15(17,18)10-3-4-11(12(6-10)14(22)23)13(21)20-8-9-2-1-5-19-7-9/h1-7H,8H2,(H,20,21)(H,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
4.57E+3n/a 4.80E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159213
PNG
(US9682967, 42)
Show SMILES CC(=C)c1ccc(C(=O)Nc2cccc(C)n2)c(c1)C(O)=O
Show InChI InChI=1S/C17H16N2O3/c1-10(2)12-7-8-13(14(9-12)17(21)22)16(20)19-15-6-4-5-11(3)18-15/h4-9H,1H2,2-3H3,(H,21,22)(H,18,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
4.95E+3n/a 5.20E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159162
PNG
(US9682967, 26)
Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1cccnc1
Show InChI InChI=1S/C13H9BrN2O3/c14-8-3-4-10(11(6-8)13(18)19)12(17)16-9-2-1-5-15-7-9/h1-7H,(H,16,17)(H,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
5.24E+3n/a 5.50E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445056
PNG
(CHEMBL3098743 | US9682967, 3)
Show SMILES Cc1ccc(C(=O)Nc2cccc(C)n2)c(c1)C(O)=O
Show InChI InChI=1S/C15H14N2O3/c1-9-6-7-11(12(8-9)15(19)20)14(18)17-13-5-3-4-10(2)16-13/h3-8H,1-2H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
US Patent
6.10E+3n/a 6.40E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159202
PNG
(US9682967, 39)
Show SMILES OC(=O)c1cc(ccc1C(=O)NCc1ccncc1)C(F)(F)F
Show InChI InChI=1S/C15H11F3N2O3/c16-15(17,18)10-1-2-11(12(7-10)14(22)23)13(21)20-8-9-3-5-19-6-4-9/h1-7H,8H2,(H,20,21)(H,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
7.14E+3n/a 7.50E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM159110
PNG
(US9682967, 6)
Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1sc2CCCCc2c1C#N
Show InChI InChI=1S/C17H13BrN2O3S/c18-9-5-6-11(12(7-9)17(22)23)15(21)20-16-13(8-19)10-3-1-2-4-14(10)24-16/h5-7H,1-4H2,(H,20,21)(H,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 4.00E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%