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Found 17 Enz. Inhib. hit(s) with all data for entry = 33
TargetGag-Pol polyprotein [588-1147,K652R,M771V](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77092(CMX-157 | CMX157 | HDP-tenofovir | Tenofovir Exali...)
Affinity DataIC50:  1.80nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,M628L,D654N,M771V,L797W,T802Y](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77092(CMX-157 | CMX157 | HDP-tenofovir | Tenofovir Exali...)
Affinity DataIC50:  3.10nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,M628L,N654N,K657R,T802F,K807E](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77092(CMX-157 | CMX157 | HDP-tenofovir | Tenofovir Exali...)
Affinity DataIC50:  3.80nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,V662I,F664L,F703Y,Q738M,M771V](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77092(CMX-157 | CMX157 | HDP-tenofovir | Tenofovir Exali...)
Affinity DataIC50:  5nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,M628L,T656S,M771V,L797W,T802Y](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77092(CMX-157 | CMX157 | HDP-tenofovir | Tenofovir Exali...)
Affinity DataIC50:  9nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,M628L,D654N,M771V,L797W,T802Y](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77092(CMX-157 | CMX157 | HDP-tenofovir | Tenofovir Exali...)
Affinity DataIC50:  19nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,K652R,M771V](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50:  1.04E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,M628L,D654N,M771V,L797W,T802Y](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50:  5.39E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,M628L,T656S,M771V,L797W,T802Y](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: >6.47E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,V662I,F664L,F703Y,Q738M,M771V](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: >6.49E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,M628L,N654N,K657R,T802F,K807E](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50:  6.52E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGag-Pol polyprotein [588-1147,M628L,D654N,M771V,L797W,T802Y](Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: >8.51E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataEC50:  3nMAssay Description:The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77141(CMX157 ion)
Affinity DataEC50: <30nMAssay Description:The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77097(CMX157-210)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77105(CMX157-211)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Chimerix

US Patent
LigandPNGBDBM77108(CMX157-220)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...More data for this Ligand-Target Pair
In DepthDetails US Patent