Found 15 Enz. Inhib. hit(s) with all data for entry = 53 
Affinity DataIC50: 0.230nMT: 2°CAssay Description:Enzymatic activity was tested in 96-well or 384-well flat microwell plate by fluorescence detection and taking Ac-Lys-Tyr-Lys(Ac)-AMC as substrate. T...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.470nMT: 2°CAssay Description:Enzymatic activity was tested in 96-well or 384-well flat microwell plate by fluorescence detection and taking Ac-Lys-Tyr-Lys(Ac)-AMC as substrate. T...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Double Rider Medicine
US Patent
Double Rider Medicine
US Patent
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09nMT: 2°CAssay Description:Enzymatic activity was tested in 96-well or 384-well flat microwell plate by fluorescence detection and taking Ac-Lys-Tyr-Lys(Ac)-AMC as substrate. T...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Double Rider Medicine
US Patent
Double Rider Medicine
US Patent
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Double Rider Medicine
US Patent
Double Rider Medicine
US Patent
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Double Rider Medicine
US Patent
Double Rider Medicine
US Patent
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Double Rider Medicine
US Patent
Double Rider Medicine
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Double Rider Medicine
US Patent
Double Rider Medicine
US Patent
Affinity DataIC50: 6.40nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
Affinity DataIC50: 8.65nMT: 2°CAssay Description:Enzymatic activity was tested in 96-well or 384-well flat microwell plate by fluorescence detection and taking Ac-Lys-Tyr-Lys(Ac)-AMC as substrate. T...More data for this Ligand-Target Pair
Affinity DataIC50: 13.8nMT: 2°CAssay Description:Enzymatic activity was tested in 96-well or 384-well flat microwell plate by fluorescence detection and taking Ac-Lys-Tyr-Lys(Ac)-AMC as substrate. T...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Double Rider Medicine
US Patent
Double Rider Medicine
US Patent
Affinity DataIC50: 99.9nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Double Rider Medicine
US Patent
Double Rider Medicine
US Patent
Affinity DataIC50: 146nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Double Rider Medicine
US Patent
Double Rider Medicine
US Patent
Affinity DataIC50: 572nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Double Rider Medicine
US Patent
Double Rider Medicine
US Patent
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
