Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 254
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255777(3-(3-(4-n-Octylphenyl)ureido)propanoic acid | US97...)
Affinity DataEC50:  460nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255789(2-Amino-2-(5-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiaz...)
Affinity DataEC50:  380nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255776(2-(4-(4-n-Octylphenyl)piperazin-1-yl)acetic acid |...)
Affinity DataEC50:  1.63E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255778(3-(3-(4-Octylphenyl)-2-oxoimidazolidin-1-yl)propan...)
Affinity DataEC50:  3.21E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255779(US9707205, 17)
Affinity DataEC50:  1.76E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255780(4-(4-(3-(3-(2,2,2-trifluoroacetyl)-1H-indol-1-yl)p...)
Affinity DataEC50:  5.99E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255781(1-((4′-(((4-Fluorophenyl)(isopropyl)amino)me...)
Affinity DataEC50:  600nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255782(1-((4′-(3-(3-(Trifluoromethyl)phenyl)but-2-e...)
Affinity DataEC50:  200nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255783(1-(4-(3-(1-Admantnyl)-4-methoxybenzyloxy)benzyl)az...)
Affinity DataEC50:  60nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255784(1-(4-(2-(6,6-Dimethylbicyclo[3.1.1]heptan-2-yl)eth...)
Affinity DataEC50:  140nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255785(2-Amino-2-(5-(5-(3-chloro-4-propoxyphenyl)-1,2,4-o...)
Affinity DataEC50:  47nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255786( (E)-2-Amino-2-(5-(5-(4-methylstyryl)-1,2,4-oxadia...)
Affinity DataEC50:  1.82E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255787( 2-Amino-2-(5-(5-(4-bromo-3-chlorophenyl)-1,2,4-ox...)
Affinity DataEC50:  260nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255788(2-Amino-2-(5-(5-(3-chloro-4-(thiophen-3-yl)phenyl)...)
Affinity DataEC50:  3.46E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255789(2-Amino-2-(5-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiaz...)
Affinity DataEC50:  57nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Akaal Pharma

US Patent
LigandPNGBDBM255775(N-(1H-Tetrazol-5-yl)methyl-4-octylbenzylamine | US...)
Affinity DataEC50:  290nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent