BindingDB logo
myBDB logout

Patent code US9713612

Compile Data Set for Download or QSAR
Found 30 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Wnt-3a


(Homo sapiens)
BDBM263598
PNG
(US9713612, 96)
Show SMILES Cc1cc(ccn1)-c1cc2ccnc(NCc3cnc(c(C)c3)-c3ccnc(C)c3)c2cn1
Show InChI InChI=1S/C27H24N6/c1-17-10-20(14-32-26(17)23-6-8-29-19(3)12-23)15-33-27-24-16-31-25(13-21(24)4-9-30-27)22-5-7-28-18(2)11-22/h4-14,16H,15H2,1-3H3,(H,30,33)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263599
PNG
(US9713612, 97)
Show SMILES Cc1cc(ccn1)-c1cc2ccnc(NCc3cnc(c(F)c3)-c3ccnc(C)c3)c2cn1
Show InChI InChI=1S/C26H21FN6/c1-16-9-20(4-6-28-16)24-12-19-3-8-30-26(22(19)15-31-24)33-14-18-11-23(27)25(32-13-18)21-5-7-29-17(2)10-21/h3-13,15H,14H2,1-2H3,(H,30,33)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263603
PNG
(US9713612, 110)
Show SMILES Cc1cc(ccn1)-c1cc2ccnc(NCc3cnc(c(Cl)c3)-c3ccnc(C)c3)c2cn1
Show InChI InChI=1S/C26H21ClN6/c1-16-9-20(4-6-28-16)24-12-19-3-8-30-26(22(19)15-31-24)33-14-18-11-23(27)25(32-13-18)21-5-7-29-17(2)10-21/h3-13,15H,14H2,1-2H3,(H,30,33)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263586
PNG
(US9713612, 35)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ncc23)-c2cnccn2)cc1
Show InChI InChI=1S/C25H20N6/c1-17-12-20(6-8-27-17)19-4-2-18(3-5-19)14-31-25-22-15-30-23(13-21(22)7-9-29-25)24-16-26-10-11-28-24/h2-13,15-16H,14H2,1H3,(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a<3n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263579
PNG
(US9713612, 14)
Show SMILES Cc1cncc(c1)-c1cc2ccnc(NCc3ccc(cc3)-c3ccnc(C)c3)c2cn1
Show InChI InChI=1S/C27H23N5/c1-18-11-24(16-28-14-18)26-13-23-8-10-30-27(25(23)17-31-26)32-15-20-3-5-21(6-4-20)22-7-9-29-19(2)12-22/h3-14,16-17H,15H2,1-2H3,(H,30,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 3n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263584
PNG
(US9713612, 28)
Show SMILES Cc1cc(ccn1)-c1cc2ccnc(NCc3ccc(c(F)c3)-c3ccnc(F)c3)c2cn1
Show InChI InChI=1S/C26H19F2N5/c1-16-10-20(6-7-29-16)24-12-18-5-9-31-26(22(18)15-32-24)33-14-17-2-3-21(23(27)11-17)19-4-8-30-25(28)13-19/h2-13,15H,14H2,1H3,(H,31,33)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a<3n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263572
PNG
(Synthesis of N-(4-(2-methylpyridin-4-yl)benzyl)-6-...)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ncc23)-c2ccnc(C)c2)cc1
Show InChI InChI=1S/C27H23N5/c1-18-13-22(7-10-28-18)21-5-3-20(4-6-21)16-32-27-25-17-31-26(15-23(25)8-12-30-27)24-9-11-29-19(2)14-24/h3-15,17H,16H2,1-2H3,(H,30,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a<3n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263573
PNG
(Synthesis of N-(3-methyl-4-(2-methylpyridin-4-yl)b...)
Show SMILES Cc1cc(ccn1)-c1cc2ccnc(NCc3ccc(c(C)c3)-c3ccnc(C)c3)c2cn1
Show InChI InChI=1S/C28H25N5/c1-18-12-21(4-5-25(18)22-6-9-29-19(2)13-22)16-33-28-26-17-32-27(15-23(26)7-11-31-28)24-8-10-30-20(3)14-24/h4-15,17H,16H2,1-3H3,(H,31,33)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a<3n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263595
PNG
(US9713612, 70)
Show SMILES Cc1cc(ccn1)-c1ncc(CNc2nccc3cc(ccc23)-c2cnccn2)cc1C
Show InChI InChI=1S/C26H22N6/c1-17-11-19(14-31-25(17)22-6-7-28-18(2)12-22)15-32-26-23-4-3-21(13-20(23)5-8-30-26)24-16-27-9-10-29-24/h3-14,16H,15H2,1-2H3,(H,30,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a<3n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263575
PNG
(Synthesis of N-(4-(2-methylpyridin-4-yl)benzyl)-2-...)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3nc(ccc23)-c2ccnc(C)c2)cc1
Show InChI InChI=1S/C27H23N5/c1-18-15-22(9-12-28-18)21-5-3-20(4-6-21)17-31-27-24-7-8-25(32-26(24)11-14-30-27)23-10-13-29-19(2)16-23/h3-16H,17H2,1-2H3,(H,30,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263582
PNG
(US9713612, 22)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ncc23)-c2ccnc(F)c2)cc1
Show InChI InChI=1S/C26H20FN5/c1-17-12-20(6-9-28-17)19-4-2-18(3-5-19)15-32-26-23-16-31-24(13-21(23)7-11-30-26)22-8-10-29-25(27)14-22/h2-14,16H,15H2,1H3,(H,30,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263591
PNG
(US9713612, 61)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ccc23)-c2ccnc(C)c2)cc1
Show InChI InChI=1S/C28H24N4/c1-19-15-24(9-12-29-19)22-5-3-21(4-6-22)18-32-28-27-8-7-23(17-26(27)11-14-31-28)25-10-13-30-20(2)16-25/h3-17H,18H2,1-2H3,(H,31,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263592
PNG
(US9713612, 63)
Show SMILES Cc1ccc(cn1)-c1ccc2c(NCc3ccc(cc3)-c3ccnc(C)c3)nccc2c1
Show InChI InChI=1S/C28H24N4/c1-19-3-6-26(18-31-19)23-9-10-27-25(16-23)12-14-30-28(27)32-17-21-4-7-22(8-5-21)24-11-13-29-20(2)15-24/h3-16,18H,17H2,1-2H3,(H,30,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263600
PNG
(US9713612, 104)
Show SMILES Cc1cc(ccn1)-c1cc2ccnc(NCc3ccc(cc3)-c3cc[n+]([O-])c(C)c3)c2cn1
Show InChI InChI=1S/C27H23N5O/c1-18-13-24(8-10-28-18)26-15-23-7-11-29-27(25(23)17-30-26)31-16-20-3-5-21(6-4-20)22-9-12-32(33)19(2)14-22/h3-15,17H,16H2,1-2H3,(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263596
PNG
(US9713612, 75)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3nc(cnc23)-c2cccc(F)c2)cc1
Show InChI InChI=1S/C26H20FN5/c1-17-13-20(9-11-28-17)19-7-5-18(6-8-19)15-31-26-25-23(10-12-29-26)32-24(16-30-25)21-3-2-4-22(27)14-21/h2-14,16H,15H2,1H3,(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263601
PNG
(US9713612, 108)
Show SMILES Cc1cc(ccn1)-c1cc2ccnc(NCc3ccc(-c4ccnc(C)c4)c(c3)C#N)c2cn1
Show InChI InChI=1S/C28H22N6/c1-18-11-21(5-8-30-18)25-4-3-20(13-24(25)15-29)16-34-28-26-17-33-27(14-22(26)6-10-32-28)23-7-9-31-19(2)12-23/h3-14,17H,16H2,1-2H3,(H,32,34)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 8n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263578
PNG
(US9713612, 9)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ncc23)-c2cccc(F)c2)cc1
Show InChI InChI=1S/C27H21FN4/c1-18-13-21(9-11-29-18)20-7-5-19(6-8-20)16-32-27-25-17-31-26(15-22(25)10-12-30-27)23-3-2-4-24(28)14-23/h2-15,17H,16H2,1H3,(H,30,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263574
PNG
(Synthesis of 6-(3-fluorophenyl)-N-((6-(2-methylpyr...)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ccc23)-c2cccc(F)c2)cn1
Show InChI InChI=1S/C27H21FN4/c1-18-13-23(10-11-29-18)26-8-5-19(16-31-26)17-32-27-25-7-6-21(14-22(25)9-12-30-27)20-3-2-4-24(28)15-20/h2-16H,17H2,1H3,(H,30,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263594
PNG
(US9713612, 69)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ccc23)-c2cnccn2)cn1
Show InChI InChI=1S/C25H20N6/c1-17-12-21(7-8-27-17)23-5-2-18(14-30-23)15-31-25-22-4-3-20(13-19(22)6-9-29-25)24-16-26-10-11-28-24/h2-14,16H,15H2,1H3,(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263597
PNG
(US9713612, 84)
Show SMILES CC1CN(CCO1)c1cc2ccnc(NCc3ccc(cc3)-c3ccnc(C)c3)c2cn1
Show InChI InChI=1S/C26H27N5O/c1-18-13-22(7-9-27-18)21-5-3-20(4-6-21)15-30-26-24-16-29-25(14-23(24)8-10-28-26)31-11-12-32-19(2)17-31/h3-10,13-14,16,19H,11-12,15,17H2,1-2H3,(H,28,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263580
PNG
(US9713612, 16)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ncc23)-c2cccc(c2)C#N)cc1
Show InChI InChI=1S/C28H21N5/c1-19-13-23(9-11-30-19)22-7-5-20(6-8-22)17-33-28-26-18-32-27(15-24(26)10-12-31-28)25-4-2-3-21(14-25)16-29/h2-15,18H,17H2,1H3,(H,31,33)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263587
PNG
(US9713612, 37)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ncc23)N2CCOCC2)cc1
Show InChI InChI=1S/C25H25N5O/c1-18-14-21(6-8-26-18)20-4-2-19(3-5-20)16-29-25-23-17-28-24(15-22(23)7-9-27-25)30-10-12-31-13-11-30/h2-9,14-15,17H,10-13,16H2,1H3,(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263583
PNG
(US9713612, 23)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ncc23)-c2ccccc2F)cc1
Show InChI InChI=1S/C27H21FN4/c1-18-14-21(10-12-29-18)20-8-6-19(7-9-20)16-32-27-24-17-31-26(15-22(24)11-13-30-27)23-4-2-3-5-25(23)28/h2-15,17H,16H2,1H3,(H,30,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263593
PNG
(US9713612, 68)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ccc23)-c2ccnnc2)cc1
Show InChI InChI=1S/C26H21N5/c1-18-14-22(8-11-27-18)20-4-2-19(3-5-20)16-29-26-25-7-6-21(15-23(25)9-12-28-26)24-10-13-30-31-17-24/h2-15,17H,16H2,1H3,(H,28,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263590
PNG
(US9713612, 50)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3nc(ccc23)-c2cccc(F)c2)cn1
Show InChI InChI=1S/C26H20FN5/c1-17-13-20(9-11-28-17)23-7-5-18(15-30-23)16-31-26-22-6-8-24(32-25(22)10-12-29-26)19-3-2-4-21(27)14-19/h2-15H,16H2,1H3,(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 35n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263585
PNG
(US9713612, 33)
Show SMILES Cc1cc(ccn1)-c1cc2ccnc(NCc3ccc(nc3)N3CCS(=O)(=O)CC3)c2cn1
Show InChI InChI=1S/C24H24N6O2S/c1-17-12-20(5-6-25-17)22-13-19-4-7-26-24(21(19)16-27-22)29-15-18-2-3-23(28-14-18)30-8-10-33(31,32)11-9-30/h2-7,12-14,16H,8-11,15H2,1H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 50n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263581
PNG
(US9713612, 20)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3ccncc23)cc1
Show InChI InChI=1S/C21H18N4/c1-15-12-19(8-10-23-15)17-4-2-16(3-5-17)13-25-21-20-14-22-9-6-18(20)7-11-24-21/h2-12,14H,13H2,1H3,(H,24,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 50n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263577
PNG
(Synthesis of N-(4-(2-methylpyridin-4-yl)benzyl)-2-...)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3nc(cnc23)-c2ccccc2)cc1
Show InChI InChI=1S/C26H21N5/c1-18-15-22(11-13-27-18)20-9-7-19(8-10-20)16-30-26-25-23(12-14-28-26)31-24(17-29-25)21-5-3-2-4-6-21/h2-15,17H,16H2,1H3,(H,28,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 70n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263588
PNG
(US9713612, 39)
Show SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ncc23)N2CCS(=O)(=O)CC2)cc1
Show InChI InChI=1S/C25H25N5O2S/c1-18-14-21(6-8-26-18)20-4-2-19(3-5-20)16-29-25-23-17-28-24(15-22(23)7-9-27-25)30-10-12-33(31,32)13-11-30/h2-9,14-15,17H,10-13,16H2,1H3,(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 70n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens)
BDBM263589
PNG
(US9713612, 47)
Show SMILES Cc1ccc(CNc2nccc3cc(ncc23)-c2ccnc(C)c2)cc1
Show InChI InChI=1S/C22H20N4/c1-15-3-5-17(6-4-15)13-26-22-20-14-25-21(12-18(20)7-10-24-22)19-8-9-23-16(2)11-19/h3-12,14H,13H2,1-2H3,(H,24,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 1.25E+3n/an/an/an/an/an/a



CUREGENIX, INC.

US Patent


Assay Description
Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...


US Patent US9713612 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%