Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 374
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264170((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50:  1.20nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264162((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-met...)
Affinity DataIC50:  1.40nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264168((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tet...)
Affinity DataIC50:  1.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264129((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methox...)
Affinity DataIC50:  1.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264129((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methox...)
Affinity DataIC50:  1.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264160((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-ethoxy...)
Affinity DataIC50:  1.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264162((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-met...)
Affinity DataIC50:  1.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264160((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-ethoxy...)
Affinity DataIC50:  2nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264128((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methoxyq...)
Affinity DataIC50:  2.30nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264169((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50:  2.70nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264175((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50:  2.80nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264175((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50:  2.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264168((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tet...)
Affinity DataIC50:  2.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264170((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50:  2.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264167((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tet...)
Affinity DataIC50:  3.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264163((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-met...)
Affinity DataIC50:  4.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264173((E)-N-(7-(((S)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50:  4.80nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264128((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methoxyq...)
Affinity DataIC50:  5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264173((E)-N-(7-(((S)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50:  5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264163((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-met...)
Affinity DataIC50:  5.80nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264165((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclo...)
Affinity DataIC50:  6.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264161((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-ethoxy...)
Affinity DataIC50:  7.80nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264161((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-ethoxy...)
Affinity DataIC50:  8.10nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264164((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclopr...)
Affinity DataIC50:  9.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264167((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tet...)
Affinity DataIC50:  9.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264174((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50:  10.8nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264174((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50:  11.2nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264171((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50:  11.2nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264164((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclopr...)
Affinity DataIC50:  11.8nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264169((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50:  13.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264159((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methox...)
Affinity DataIC50:  14.2nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264165((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclo...)
Affinity DataIC50:  15.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264176((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50:  15.6nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264172((E)-N-(7-(((S)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50:  17.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264159((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methox...)
Affinity DataIC50:  21.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264166((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclo...)
Affinity DataIC50:  21.7nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264176((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50:  22.2nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264171((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50:  25nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264166((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclo...)
Affinity DataIC50:  32.8nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264172((E)-N-(7-(((S)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50:  39.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent