Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 1538
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM330295(Methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)me...)
Affinity DataIC50:  2.84nMAssay Description:The activity of purified kinase was detected with Kinase-GloŽ Plus kinase luminescent assay by measuring the amount of the remaining Kinase in the so...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM330296((S)-methyl (5-(4-(3-methylmorpholino)-6-((4-(methy...)
Affinity DataIC50:  5.67nMAssay Description:The activity of purified kinase was detected with Kinase-GloŽ Plus kinase luminescent assay by measuring the amount of the remaining Kinase in the so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM330294(Ethyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)met...)
Affinity DataIC50:  7.15nMAssay Description:The activity of purified kinase was detected with Kinase-GloŽ Plus kinase luminescent assay by measuring the amount of the remaining Kinase in the so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM330293(1-ethyl-3-(5-(6-((4-(methylsulfonyl)piperazin-1-yl...)
Affinity DataIC50:  8.19nMAssay Description:The activity of purified kinase was detected with Kinase-GloŽ Plus kinase luminescent assay by measuring the amount of the remaining Kinase in the so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM330259(5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-...)
Affinity DataIC50:  8.37nMAssay Description:The activity of purified kinase was detected with Kinase-GloŽ Plus kinase luminescent assay by measuring the amount of the remaining Kinase in the so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM330292(1-(4-fluorophenyl)-3-(5-(6-((4-(methylsulfonyl)pip...)
Affinity DataIC50:  9.30nMAssay Description:The activity of purified kinase was detected with Kinase-GloŽ Plus kinase luminescent assay by measuring the amount of the remaining Kinase in the so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM330258(1-(4-(4-methylpiperazine-carbonyl)phenyl)-3-(4-(6-...)
Affinity DataIC50:  9.59nMAssay Description:The activity of purified kinase was detected with Kinase-GloŽ Plus kinase luminescent assay by measuring the amount of the remaining Kinase in the so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent