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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333639 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333645 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333649 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333651 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333653 (1-(3-tert- butylisoxazol- 5-yl)-3-(3- (6-methoxy- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333508 (1-(5-tert- Butylisoxazol- 3-yl)-3-[3- (7-ethoxy-6-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333510 (1-(5-tert- butylisoxazol- 3-yl)-3-{3- [6-methoxy- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333513 (1-(5-tert- Butylisoxazol- 3-yl)-3-{3- [7-methoxy- ...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333518 (1-(5-tert- Butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333519 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoixy-...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333502 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333525 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-(2-(4- (h...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333654 (1-(3-(6- Methoxy-7- (2- methoxyethoxy) quinazolin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333713 (1-(3-(7- hydroxy-6- methoxy- quinazolin- 4- yloxy)...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333714 (1-(3-(6- hydroxy-7- methoxy- quinazolin- 4- yloxy)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333715 (1-(3-(6,7- dimethoxy- quinazolin- 4- yloxy)-2- flu...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333717 (1-(3-(6,7- dimethoxy- quinazolin- 4- yloxy)phenyl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333724 (1-(3-tert- butyl-1-p- tolyl-1H- pyrazol-5-yl)- 3-(...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333726 (1-(3-tert- butyl-1-p- tolyl-1H- pyrazol-5-yl)- 3-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333726 (1-(3-tert- butyl-1-p- tolyl-1H- pyrazol-5-yl)- 3-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333728 (1-(3-(2-cyano- propan- 2- yl)phenyl)-3- (3-(6,7- d...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333526 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333528 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333529 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333533 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-(3-(4- (h...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333534 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-(3-(4-(2-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333536 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333537 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333539 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333540 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333541 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-(2-(4-(2-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333658 (1-{3-[6- methoxy-7- (2- methoxyethoxy) quinazolin-...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333658 (1-{3-[6- methoxy-7- (2- methoxyethoxy) quinazolin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333661 (1-(3-(1,1- difluoroethyl) isoxazol- 5- yl)-3-(3-(6...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333664 (1-(3- cyclopropyl- isoxazol- 5- yl)-3-(3-(6- metho...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333665 (1-(3- isopropylisoxazol- 5-yl)- 3-(3-(6-methoxy- 7...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333667 (1-(5-(1- methoxy-2- methylpropan-2- yl)isoxazol- 3...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333669 (1-(5- cyclopentyl- isoxazol- 3-yl)- 3-(3-(6- metho...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333671 (1-{3-[6- methoxy-7- (2- methoxyethoxy) quinazolin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333672 (1-(3-fluoro-4- (trifluoromethyl) phenyl)- 3-(3-(6-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333673 (1-(3- methoxy-4- (trifluoromethyl) phenyl)- 3-(3-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333543 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-(2- metho...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333546 (1-(5-tert- Butyl- isoxazol-3- yl)-3-(3-{6- [3-(1,1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333555 ((R)-1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-(2- h...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333556 (1-(3-tert- Butylisoxazol- 5-yl)-3-(3- (6-methoxy- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333557 (1-(3-tert- butylisoxazol- 5-yl)-3-(3- (6-methoxy- ...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333559 ((S)-1-(5-tert- Butylisoxazol- 3-yl)-3-(3- {6-metho...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| B-RAF V600E (Homo sapiens (Human)) | BDBM333679 (1-(3-(6- methoxy-7- (2- methoxyethoxy) quinazolin-...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333683 (1-(3- methoxy-4- (trifluoromethyl) phenyl)-3- (3-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333685 (1-(5- cyclopentyl- isoxazol- 3- yl)-3-(3-(6- metho...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Corporation US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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