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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335414 (4-(2-{(3S)-8-chloro-7-[5-chloro-2-(1H-tetrazol-1-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335416 (5-(2-{(3S)-7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335412 (4-(2-{(3S)-7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335399 ((3S)-3-[5-(6-amino-3-pyridinyl)-4-chloro-1H-imidaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335418 (4-(2-{(3S)-7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335413 (5-(2-{(3S)-8-chloro-7-[5-chloro-2-(1H-tetrazol-1-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335419 (4-(5-{7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]-5-ox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335415 (4-(2-{(6S)-2-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335393 (US9732085, 57 | methyl{4-[5-chloro-2-({4-[5-chloro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335393 (US9732085, 57 | methyl{4-[5-chloro-2-({4-[5-chloro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335408 (US9732085, 290 | methyl[4-(2-{(3S)-7-[5-chloro-2-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335400 ((3S)-3-[5-(6-amino-2-chloro-3-pyridinyl)-1H-imidaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335420 (US9732085, Comp Ex 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335401 ((3S)-3-[5-(6-amino-2-fluoro-3-pyridinyl)-1H-imidaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335396 (6-(2-{7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]-5-ox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335411 (5-(2-{(3S)-7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335397 (US9732085, 129(2) | isopropyl[4-(2-{7-[5-chloro-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335403 (US9732085, 241 | methyl[4-(4-chloro-5-{7-[5-chloro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335410 (US9732085, 310 | methyl[4-(2-{(3S)-7-[5-chloro-2-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335407 (US9732085, 278 | methyl(4-{2-[1-{4-[5-chloro-2-(1H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335405 (US9732085, 264 | methyl{4-[4-chloro-2-(1-{4-[5-chl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335391 (US9732085, 41 | methyl[4-(2-{2-[5-chloro-2-(1H-tet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335391 (US9732085, 41 | methyl[4-(2-{2-[5-chloro-2-(1H-tet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335394 (US9732085, 60 | methyl{4-[5-chloro-2-(1-{4-[5-chlo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335409 (US9732085, 309 | methyl[4-(2-{(3S)-7-[5-methyl-2-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335402 (US9732085, 230 | methyl[6-(4-chloro-2-{(3S)-7-[5-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335406 (US9732085, 270 | methyl[4-(2-{(3R)-7-[5-chloro-2-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335417 (4-[2-({4-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]-6-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335395 (US9732085, 61 | methyl{4-[2-(1-{4-[5-chloro-2-(1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335392 (US9732085, 45) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335392 (US9732085, 45) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335404 (US9732085, 245 | methyl[4-(5-{7-[5-chloro-2-(1H-te...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335421 (US9732085, Comp Ex 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335398 (US9732085, 181 | methyl[5-(2-{7-[5-chloro-2-(1H-te...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335422 (US9732085, Comp Ex 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor XI (Homo sapiens (Human)) | BDBM335423 (US9732085, Comp. Ex 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6... | US Patent US9732085 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
