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Found 30 Enz. Inhib. hit(s) with all data for entry = 1657
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335426(4-[(3R)-3-(Methylamino)pyrrolidin-1-yl]-N-[(1R,2R,...)
Affinity DataKi:  0.5nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061098(CHEMBL3393534 | US9732087, 1)
Affinity DataKi:  1nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335425(4-[(3R)-3-(Methylamino)pyrrolidin-1-yl]-N-[(1S,2S,...)
Affinity DataKi:  1nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061008(CHEMBL3393556 | US9732087, 96)
Affinity DataKi:  1nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061143(CHEMBL3393526 | US9732087, 22)
Affinity DataKi:  1.70nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061056(CHEMBL3393542 | US9732087, 73)
Affinity DataKi:  2nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061060(CHEMBL3393539 | US9732087, 32)
Affinity DataKi:  3.08nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335429(4-[(3R)-3-Aminopyrrolidin-1-yl]-N-(2-methylpropyl)...)
Affinity DataKi:  3.5nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335450(N-Cyclohexyl-5-[(3R)-3-(methylamino)pyrrolidin-1-y...)
Affinity DataKi:  4.80nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335449(5-[(3R)-3-(Methylamino)pyrrolidin-1-yl]-N-[(1S,2S,...)
Affinity DataKi:  5.90nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335442(Cyclopropylmethyl-(4-piperazin-1-yl-pyrimidin-2-yl...)
Affinity DataKi:  12.2nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061014(CHEMBL3393550 | US9732087, 95)
Affinity DataKi:  15nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335451(N-(Cyclopropylmethyl)-5-[(3R)-3-(methylamino)pyrro...)
Affinity DataKi:  23.9nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061070(CHEMBL3393536 | US9732087, 53)
Affinity DataKi:  24.3nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335435(N-(Cyclopropylmethyl)-4-piperazin-1-ylpyridin-2-am...)
Affinity DataKi:  25.6nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335445(4-(3-Aminoazetidin-1-yl)-N-(2-methylpropyl)pyrimid...)
Affinity DataKi:  26.2nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335452(N-Butyl-5-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyr...)
Affinity DataKi:  31nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061018(CHEMBL3393546 | US9732087, 44)
Affinity DataKi:  31.5nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335440((2,2-Dimethyl-propyl)-(4-piperazin-1-yl-pyrimidin-...)
Affinity DataKi:  39nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335432(4-[(3R)-3-Aminopyrrolidin-1-yl]-N-(tetrahydro-2H-p...)
Affinity DataKi:  42.4nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335428(N-(2-Methylpropyl)-4-piperazin-1-ylpyridin-2-amine...)
Affinity DataKi:  45.3nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335441(Isobutyl-(4-piperazin-1-yl-pyrimidin-2-yl)-amine |...)
Affinity DataKi:  46.3nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061144(CHEMBL3393525 | US9732087, 21)
Affinity DataKi:  51.4nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061142(CHEMBL3393527 | US9732087, 15)
Affinity DataKi:  54.3nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335446(4-(3-Aminoazetidin-1-yl)-N-(1-methylethyl)pyrimidi...)
Affinity DataKi:  68.9nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061065(CHEMBL3393538 | US9732087, 31)
Affinity DataKi:  69nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335436(N-Butyl-4-piperazin-1-ylpyridin-2-amine | US973208...)
Affinity DataKi:  91.3nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335439(4-[(3R)-3-Aminopyrrolidin-1-yl]-N-cyclopropylpyrim...)
Affinity DataKi:  138nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335443(Bicyclo[2.2.1]hept-2-yl-(4-piperazin-1-yl-pyrimidi...)
Affinity DataKi:  240nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50061015(CHEMBL3393549 | US9732087, 101)
Affinity DataKi:  1.00E+4nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent