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Patent code US9732092

Compile Data Set for Download or QSAR
Found 23 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335495
PNG
((2R,5S,13aR)—N-(2-chloro-4-fluorobenzyl)-8-hy...)
Show SMILES Oc1c2C(=O)N3[C@H]4CC[C@H](C4)O[C@@H]3Cn2cc(C(=O)NCc2ccc(F)cc2Cl)c1=O
Show InChI InChI=1S/C21H19ClFN3O5/c22-15-5-11(23)2-1-10(15)7-24-20(29)14-8-25-9-16-26(12-3-4-13(6-12)31-16)21(30)17(25)19(28)18(14)27/h1-2,5,8,12-13,16,28H,3-4,6-7,9H2,(H,24,29)/t12-,13+,16+/m0/s1
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n/an/a 42n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330054
PNG
((2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,5-trifluor...)
Show SMILES Oc1c2C(=O)N3[C@H]4CC[C@H](C4)O[C@@H]3Cn2cc(C(=O)NCc2cc(F)c(F)cc2F)c1=O
Show InChI InChI=1S/C21H18F3N3O5/c22-13-5-15(24)14(23)3-9(13)6-25-20(30)12-7-26-8-16-27(10-1-2-11(4-10)32-16)21(31)17(26)19(29)18(12)28/h3,5,7,10-11,16,29H,1-2,4,6,8H2,(H,25,30)/t10-,11+,16+/m0/s1
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n/an/a 94n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335491
PNG
((13aS)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzy...)
Show SMILES COc1c2C(=O)N3[C@@H]4CC[C@@H](C4)O[C@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O
Show InChI InChI=1S/C22H20F3N3O5/c1-32-20-18-22(31)28-11-2-3-12(6-11)33-17(28)9-27(18)8-14(19(20)29)21(30)26-7-13-15(24)4-10(23)5-16(13)25/h4-5,8,11-12,17H,2-3,6-7,9H2,1H3,(H,26,30)/t11-,12+,17+/m1/s1
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n/an/a 137n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335488
PNG
(US9732092, Compound 40)
Show SMILES CC1C[C@H]2C[C@@H]1O[C@@H]1Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N21
Show InChI InChI=1S/C22H21F2N3O5/c1-10-4-13-6-16(10)32-17-9-26-8-14(19(28)20(29)18(26)22(31)27(13)17)21(30)25-7-11-2-3-12(23)5-15(11)24/h2-3,5,8,10,13,16-17,29H,4,6-7,9H2,1H3,(H,25,30)/t10?,13-,16-,17+/m0/s1
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n/an/a 204n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330039
PNG
((2R,5S,13aR)-N-(2,4-difluorobenzyl)-8-hydroxy-7,9-...)
Show SMILES Oc1c2C(=O)N3[C@H]4CC[C@H](C4)O[C@@H]3Cn2cc(C(=O)NCc2ccc(F)cc2F)c1=O
Show InChI InChI=1S/C21H19F2N3O5/c22-11-2-1-10(15(23)5-11)7-24-20(29)14-8-25-9-16-26(12-3-4-13(6-12)31-16)21(30)17(25)19(28)18(14)27/h1-2,5,8,12-13,16,28H,3-4,6-7,9H2,(H,24,29)/t12-,13+,16+/m0/s1
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n/an/a 240n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335482
PNG
(US9732092, Compound 3)
Show SMILES Oc1c2C(=O)N3[C@@H]4CC[C@@H](C4)O[C@@H]3Cn2cc(C(=O)NCc2ccc(F)cc2F)c1=O
Show InChI InChI=1S/C21H19F2N3O5/c22-11-2-1-10(15(23)5-11)7-24-20(29)14-8-25-9-16-26(12-3-4-13(6-12)31-16)21(30)17(25)19(28)18(14)27/h1-2,5,8,12-13,16,28H,3-4,6-7,9H2,(H,24,29)/t12-,13+,16-/m1/s1
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n/an/a 250n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335487
PNG
(US9732092, Compound 39)
Show SMILES CC1C[C@@H]2C[C@H]1O[C@H]1Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N21
Show InChI InChI=1S/C22H21F2N3O5/c1-10-4-13-6-16(10)32-17-9-26-8-14(19(28)20(29)18(26)22(31)27(13)17)21(30)25-7-11-2-3-12(23)5-15(11)24/h2-3,5,8,10,13,16-17,29H,4,6-7,9H2,1H3,(H,25,30)/t10?,13-,16-,17+/m1/s1
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n/an/a 358n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335503
PNG
((1R,4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-6,8-...)
Show SMILES Oc1c2C(=O)N3[C@@H]4CC[C@@H](CC4)[C@H]3Cn2cc(C(=O)NCc2ccc(F)cc2F)c1=O
Show InChI InChI=1S/C22H21F2N3O4/c23-13-4-1-12(16(24)7-13)8-25-21(30)15-9-26-10-17-11-2-5-14(6-3-11)27(17)22(31)18(26)20(29)19(15)28/h1,4,7,9,11,14,17,29H,2-3,5-6,8,10H2,(H,25,30)/t11-,14+,17-/m1/s1
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n/an/a 450n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330052
PNG
((1R,4S,12aS)-7-hydroxy-6,8-dioxo-N-(2,4,6-trifluor...)
Show SMILES Oc1c2C(=O)N3[C@H]4CC[C@H](C4)[C@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O
Show InChI InChI=1S/C21H18F3N3O4/c22-10-4-14(23)12(15(24)5-10)6-25-20(30)13-7-26-8-16-9-1-2-11(3-9)27(16)21(31)17(26)19(29)18(13)28/h4-5,7,9,11,16,29H,1-3,6,8H2,(H,25,30)/t9-,11+,16-/m1/s1
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n/an/a 476n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335490
PNG
((2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluor...)
Show SMILES COc1c2C(=O)N3[C@H]4CC[C@H](C4)O[C@@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O
Show InChI InChI=1S/C22H20F3N3O5/c1-32-20-18-22(31)28-11-2-3-12(6-11)33-17(28)9-27(18)8-14(19(20)29)21(30)26-7-13-15(24)4-10(23)5-16(13)25/h4-5,8,11-12,17H,2-3,6-7,9H2,1H3,(H,26,30)/t11-,12+,17+/m0/s1
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n/an/a 487n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330043
PNG
((2S,5R,13aS)-N—((S)-1-(2,4-difluorophenyl)eth...)
Show SMILES C[C@H](NC(=O)c1cn2C[C@@H]3O[C@H]4CC[C@H](C4)N3C(=O)c2c(O)c1=O)c1ccc(F)cc1F
Show InChI InChI=1S/C22H21F2N3O5/c1-10(14-5-2-11(23)6-16(14)24)25-21(30)15-8-26-9-17-27(12-3-4-13(7-12)32-17)22(31)18(26)20(29)19(15)28/h2,5-6,8,10,12-13,17,29H,3-4,7,9H2,1H3,(H,25,30)/t10-,12+,13-,17-/m0/s1
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Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335500
PNG
((1R,3R,11aS)-6-hydroxy-5,7-dioxo-N-(2,4,6-trifluor...)
Show SMILES Oc1c2C(=O)N3C4CC(C4)[C@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O
Show InChI InChI=1S/C20H16F3N3O4/c21-9-3-13(22)11(14(23)4-9)5-24-19(29)12-6-25-7-15-8-1-10(2-8)26(15)20(30)16(25)18(28)17(12)27/h3-4,6,8,10,15,28H,1-2,5,7H2,(H,24,29)/t8?,10?,15-/m1/s1
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n/an/a 1.36E+3n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330060
PNG
((1R,3S,4R,12aR)-7-hydroxy-3-methyl-6,8-dioxo-N-(2,...)
Show SMILES C[C@H]1C[C@@H]2C[C@H]1N1[C@H]2Cn2cc(C(=O)NCc3c(F)cc(F)cc3F)c(=O)c(O)c2C1=O
Show InChI InChI=1S/C22H20F3N3O4/c1-9-2-10-3-16(9)28-17(10)8-27-7-13(19(29)20(30)18(27)22(28)32)21(31)26-6-12-14(24)4-11(23)5-15(12)25/h4-5,7,9-10,16-17,30H,2-3,6,8H2,1H3,(H,26,31)/t9-,10+,16+,17-/m0/s1
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n/an/a 1.51E+3n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335483
PNG
(US9732092, Compound 5)
Show SMILES COc1c2C(=O)N3[C@H](C)CCO[C@H]3Cn2cc(C(=O)NC2(CC2)c2ccc(F)cc2F)c1=O
Show InChI InChI=1S/C23H23F2N3O5/c1-12-5-8-33-17-11-27-10-14(19(29)20(32-2)18(27)22(31)28(12)17)21(30)26-23(6-7-23)15-4-3-13(24)9-16(15)25/h3-4,9-10,12,17H,5-8,11H2,1-2H3,(H,26,30)/t12-,17+/m1/s1
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n/an/a 2.23E+3n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330047
PNG
((1R,4S,12aR)-7-hydroxy-6,8-dioxo-N-(2,4,6-trifluor...)
Show SMILES Oc1c2C(=O)N3[C@H]4CC[C@H](C4)[C@@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O
Show InChI InChI=1S/C21H18F3N3O4/c22-10-4-14(23)12(15(24)5-10)6-25-20(30)13-7-26-8-16-9-1-2-11(3-9)27(16)21(31)17(26)19(29)18(13)28/h4-5,7,9,11,16,29H,1-3,6,8H2,(H,25,30)/t9-,11+,16+/m1/s1
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n/an/a 2.82E+3n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330059
PNG
((1S,4R,12aR)-3,3-difluoro-7-hydroxy-6,8-dioxo-N-(2...)
Show SMILES Oc1c2C(=O)N3[C@@H](Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O)[C@H]1C[C@@H]3C(F)(F)C1
Show InChI InChI=1S/C21H16F5N3O4/c22-9-2-12(23)10(13(24)3-9)5-27-19(32)11-6-28-7-14-8-1-15(21(25,26)4-8)29(14)20(33)16(28)18(31)17(11)30/h2-3,6,8,14-15,31H,1,4-5,7H2,(H,27,32)/t8-,14-,15+/m0/s1
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n/an/a 3.73E+3n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330055
PNG
((1R,4S,12aR)-7-hydroxy-6,8-dioxo-N—((R)-1-(2,...)
Show SMILES C[C@@H](NC(=O)c1cn2C[C@H]3[C@@H]4CC[C@@H](C4)N3C(=O)c2c(O)c1=O)c1c(F)cc(F)cc1F
Show InChI InChI=1S/C22H20F3N3O4/c1-9(17-14(24)5-11(23)6-15(17)25)26-21(31)13-7-27-8-16-10-2-3-12(4-10)28(16)22(32)18(27)20(30)19(13)29/h5-7,9-10,12,16,30H,2-4,8H2,1H3,(H,26,31)/t9-,10-,12+,16+/m1/s1
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n/an/a 3.83E+3n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335493
PNG
((1S,4R,12aS)—N-(2,4-difluorobenzyl)-7-hydroxy...)
Show SMILES Oc1c2C(=O)N3[C@@H]4CC[C@@H](C4)[C@@H]3Cn2cc(C(=O)NCc2ccc(F)cc2F)c1=O
Show InChI InChI=1S/C21H19F2N3O4/c22-12-3-1-11(15(23)6-12)7-24-20(29)14-8-25-9-16-10-2-4-13(5-10)26(16)21(30)17(25)19(28)18(14)27/h1,3,6,8,10,13,16,28H,2,4-5,7,9H2,(H,24,29)/t10-,13+,16-/m0/s1
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n/an/a 4.91E+3n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330050
PNG
((1R,4S,12aR)-N-(2,4-difluorobenzyl)-7-hydroxy-6,8-...)
Show SMILES Oc1c2C(=O)N3[C@H]4CC[C@H](C4)[C@@H]3Cn2cc(C(=O)NCc2ccc(F)cc2F)c1=O
Show InChI InChI=1S/C21H19F2N3O4/c22-12-3-1-11(15(23)6-12)7-24-20(29)14-8-25-9-16-10-2-4-13(5-10)26(16)21(30)17(25)19(28)18(14)27/h1,3,6,8,10,13,16,28H,2,4-5,7,9H2,(H,24,29)/t10-,13+,16+/m1/s1
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 6.20E+3n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330044
PNG
( (2S,5R)-N—((S)-1-(2,4-difluorophenyl)-2,2,2-...)
Show SMILES Oc1c2C(=O)N3[C@@H]4CC[C@@H](C4)OC3Cn2cc(C(=O)N[C@@H](c2ccc(F)cc2F)C(F)(F)F)c1=O
Show InChI InChI=1S/C22H18F5N3O5/c23-9-1-4-12(14(24)5-9)19(22(25,26)27)28-20(33)13-7-29-8-15-30(10-2-3-11(6-10)35-15)21(34)16(29)18(32)17(13)31/h1,4-5,7,10-11,15,19,32H,2-3,6,8H2,(H,28,33)/t10-,11+,15?,19+/m1/s1
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UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330057
PNG
((1S,4R,12aS)-3,3-difluoro-7-hydroxy-6,8-dioxo-N-(2...)
Show SMILES Oc1c2C(=O)N3[C@H](Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O)[C@H]1C[C@@H]3C(F)(F)C1
Show InChI InChI=1S/C21H16F5N3O4/c22-9-2-12(23)10(13(24)3-9)5-27-19(32)11-6-28-7-14-8-1-15(21(25,26)4-8)29(14)20(33)16(28)18(31)17(11)30/h2-3,6,8,14-15,31H,1,4-5,7H2,(H,27,32)/t8-,14+,15+/m0/s1
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UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM335498
PNG
((1S,3R,4R,12aR)-3-fluoro-7-hydroxy-6,8-dioxo-N-(2,...)
Show SMILES Oc1c2C(=O)N3[C@@H]4C[C@@H](C[C@H]4F)[C@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O
Show InChI InChI=1S/C21H17F4N3O4/c22-9-3-12(23)10(13(24)4-9)5-26-20(31)11-6-27-7-16-8-1-14(25)15(2-8)28(16)21(32)17(27)19(30)18(11)29/h3-4,6,8,14-16,30H,1-2,5,7H2,(H,26,31)/t8-,14-,15-,16-/m1/s1
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US Patent
n/an/a 1.00E+4n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens (Human))
BDBM330042
PNG
((2S,5R,13aS)-N—((R)-1-(2,4-difluorophenyl)eth...)
Show SMILES C[C@@H](NC(=O)c1cn2C[C@@H]3O[C@H]4CC[C@H](C4)N3C(=O)c2c(O)c1=O)c1ccc(F)cc1F
Show InChI InChI=1S/C22H21F2N3O5/c1-10(14-5-2-11(23)6-16(14)24)25-21(30)15-8-26-9-17-27(12-3-4-13(7-12)32-17)22(31)18(26)20(29)19(15)28/h2,5-6,8,10,12-13,17,29H,3-4,7,9H2,1H3,(H,25,30)/t10-,12-,13+,17+/m1/s1
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US Patent
n/an/a 1.00E+4n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...


US Patent US9732092 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%