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Patent code US9738640

Compile Data Set for Download or QSAR
Found 16 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
hmuan mao-b


(Homo sapiens (Human))
BDBM335724
PNG
(US9738640, Example 1)
Show SMILES Clc1ccc(cc1Cl)C(=O)Nc1ccc2nccc2n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.13n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-b


(Homo sapiens (Human))
BDBM335725
PNG
(US9738640, Example 2)
Show SMILES Fc1ccc(cc1Cl)C(=O)Nc1ccc2nccc2n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.27n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-b


(Homo sapiens (Human))
BDBM335728
PNG
(US9738640, Example 3)
Show SMILES Fc1cc(ccc1Cl)C(=O)Nc1ccc2nccc2n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 10.9n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-b


(Homo sapiens (Human))
BDBM335732
PNG
(US9738640, Example 5)
Show SMILES Fc1cc(ccc1Cl)C(=O)Nc1ccc2n(ccc2n1)C(=O)c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C21H11Cl2F2N3O2/c22-13-3-1-11(9-15(13)24)20(29)27-19-6-5-18-17(26-19)7-8-28(18)21(30)12-2-4-14(23)16(25)10-12/h1-10H,(H,26,27,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 27.5n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-b


(Homo sapiens (Human))
BDBM335733
PNG
(US9738640, Example 6)
Show SMILES Clc1ccc(cc1Cl)C(=O)Nc1cc2cc[nH]c2cn1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 28.5n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-b


(Homo sapiens (Human))
BDBM335731
PNG
(US9738640, Example 4)
Show SMILES Fc1ccc(cc1F)C(=O)Nc1ccc2nccc2n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 46.1n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-b


(Homo sapiens (Human))
BDBM335734
PNG
(US9738640, Example 7)
Show SMILES Fc1ccc(cc1Cl)C(=O)Nc1cc2cc[nH]c2cn1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 72n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-b


(Homo sapiens (Human))
BDBM335735
PNG
(US9738640, Example 8)
Show SMILES Fc1ccc(cc1F)C(=O)Nc1cc2cc[nH]c2cn1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 277n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-a


(Homo sapiens (Human))
BDBM335732
PNG
(US9738640, Example 5)
Show SMILES Fc1cc(ccc1Cl)C(=O)Nc1ccc2n(ccc2n1)C(=O)c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C21H11Cl2F2N3O2/c22-13-3-1-11(9-15(13)24)20(29)27-19-6-5-18-17(26-19)7-8-28(18)21(30)12-2-4-14(23)16(25)10-12/h1-10H,(H,26,27,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-a


(Homo sapiens (Human))
BDBM335728
PNG
(US9738640, Example 3)
Show SMILES Fc1cc(ccc1Cl)C(=O)Nc1ccc2nccc2n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-a


(Homo sapiens (Human))
BDBM335734
PNG
(US9738640, Example 7)
Show SMILES Fc1ccc(cc1Cl)C(=O)Nc1cc2cc[nH]c2cn1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+4n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-a


(Homo sapiens (Human))
BDBM335724
PNG
(US9738640, Example 1)
Show SMILES Clc1ccc(cc1Cl)C(=O)Nc1ccc2nccc2n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-a


(Homo sapiens (Human))
BDBM335733
PNG
(US9738640, Example 6)
Show SMILES Clc1ccc(cc1Cl)C(=O)Nc1cc2cc[nH]c2cn1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+4n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-a


(Homo sapiens (Human))
BDBM335725
PNG
(US9738640, Example 2)
Show SMILES Fc1ccc(cc1Cl)C(=O)Nc1ccc2nccc2n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-a


(Homo sapiens (Human))
BDBM335731
PNG
(US9738640, Example 4)
Show SMILES Fc1ccc(cc1F)C(=O)Nc1ccc2nccc2n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
hmuan mao-a


(Homo sapiens (Human))
BDBM335735
PNG
(US9738640, Example 8)
Show SMILES Fc1ccc(cc1F)C(=O)Nc1cc2cc[nH]c2cn1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



“NTZ LAB” LTD.

US Patent


Assay Description
Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...


US Patent US9738640 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%