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Patent code US9776990

Compile Data Set for Download or QSAR
Found 146 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342609
PNG
(N-{4-[(4,4-difluorocyclohexyl)oxy]-3-(3-methyl-4-o...)
Show SMILES CCS(=O)(=O)Nc1ccc(OC2CCC(F)(F)CC2)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
9n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342604
PNG
(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Show SMILES CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
11n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342624
PNG
(N-[3-(3,6-dimethyl-4-oxo-4,5,6,7-tetrahydro-2H-iso...)
Show SMILES CC1Cc2c([nH]c(C)c2C(=O)C1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
12n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342603
PNG
(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NS(C)(=O)=O)ccc1Oc1ccc(F)cc1F
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
14n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342597
PNG
(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
15n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342604
PNG
(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Show SMILES CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

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US Patent
19n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342630
PNG
(1-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(ccc1OCC1CC1)S(C)(=O)=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
34n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342601
PNG
(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NS(C)(=O)=O)ccc1Sc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
37n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342602
PNG
(1-[5-amino-2-(2,4-difluorophenoxy)phenyl]-3-methyl...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(N)ccc1Oc1ccc(F)cc1F
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
40n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342597
PNG
(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
43n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342606
PNG
(N′-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-ox...)
Show SMILES CN(C)S(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
43n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342605
PNG
(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NS(=O)(=O)CC(F)(F)F)ccc1Oc1ccc(F)cc1F
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
43n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342611
PNG
(3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(ccc1Oc1ccccc1)C(O)=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
45n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342603
PNG
(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NS(C)(=O)=O)ccc1Oc1ccc(F)cc1F
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
52n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342623
PNG
(1-(5-amino-2-phenoxyphenyl)-3,6-dimethyl-2,5,6,7-t...)
Show SMILES CC1Cc2c([nH]c(C)c2C(=O)C1)-c1cc(N)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
58n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342601
PNG
(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NS(C)(=O)=O)ccc1Sc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
67n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342613
PNG
(3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(ccc1Oc1ccccc1)C(=O)NCC1CCCO1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
68n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342624
PNG
(N-[3-(3,6-dimethyl-4-oxo-4,5,6,7-tetrahydro-2H-iso...)
Show SMILES CC1Cc2c([nH]c(C)c2C(=O)C1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
68n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342605
PNG
(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NS(=O)(=O)CC(F)(F)F)ccc1Oc1ccc(F)cc1F
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
68n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342623
PNG
(1-(5-amino-2-phenoxyphenyl)-3,6-dimethyl-2,5,6,7-t...)
Show SMILES CC1Cc2c([nH]c(C)c2C(=O)C1)-c1cc(N)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
69n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342607
PNG
(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Show SMILES CC(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
71n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342612
PNG
(N-ethyl-3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-is...)
Show SMILES CCNC(=O)c1ccc(Oc2ccccc2)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
77n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342609
PNG
(N-{4-[(4,4-difluorocyclohexyl)oxy]-3-(3-methyl-4-o...)
Show SMILES CCS(=O)(=O)Nc1ccc(OC2CCC(F)(F)CC2)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
88n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342596
PNG
(1-(5-amino-2-phenoxyphenyl)-3-methyl-2,5,6,7-tetra...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(N)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
148n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342626
PNG
(N-{3-[3-methyl-6-(2-methylpropyl)-4-oxo-4,5,6,7-te...)
Show SMILES CC(C)CC1Cc2c([nH]c(C)c2C(=O)C1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
151n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342598
PNG
(N-[3-(2,3-dimethyl-4-oxo-4,5,6,7-tetrahydro-2H-iso...)
Show SMILES Cc1c2c(CCCC2=O)c(-c2cc(NS(C)(=O)=O)ccc2Oc2ccccc2)n1C
Show InChI InChI=1S/C23H24N2O4S/c1-15-22-18(10-7-11-20(22)26)23(25(15)2)19-14-16(24-30(3,27)28)12-13-21(19)29-17-8-5-4-6-9-17/h4-6,8-9,12-14,24H,7,10-11H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
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161n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342608
PNG
(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NC(=O)c2ccc[nH]2)ccc1Oc1ccc(F)cc1F
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
164n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342622
PNG
(3,6-dimethyl-1-(2-phenoxyphenyl)-2,5,6,7-tetrahydr...)
Show SMILES CC1Cc2c([nH]c(C)c2C(=O)C1)-c1ccccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
184n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342606
PNG
(N′-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-ox...)
Show SMILES CN(C)S(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
192n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342602
PNG
(1-[5-amino-2-(2,4-difluorophenoxy)phenyl]-3-methyl...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(N)ccc1Oc1ccc(F)cc1F
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
198n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342589
PNG
(3-methyl-1-[2-(tetrahydro-2H-pyran-4-ylmethoxy)phe...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCC1CCOCC1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
202n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342598
PNG
(N-[3-(2,3-dimethyl-4-oxo-4,5,6,7-tetrahydro-2H-iso...)
Show SMILES Cc1c2c(CCCC2=O)c(-c2cc(NS(C)(=O)=O)ccc2Oc2ccccc2)n1C
Show InChI InChI=1S/C23H24N2O4S/c1-15-22-18(10-7-11-20(22)26)23(25(15)2)19-14-16(24-30(3,27)28)12-13-21(19)29-17-8-5-4-6-9-17/h4-6,8-9,12-14,24H,7,10-11H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
216n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342519
PNG
(3-methyl-1-(2-phenoxyphenyl)-2,5,6,7-tetrahydro-4H...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
255n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342563
PNG
(3-methyl-1-(3,4,5-trimethoxyphenyl)-2,5,6,7-tetrah...)
Show SMILES COc1cc(cc(OC)c1OC)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
261n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342611
PNG
(3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(ccc1Oc1ccccc1)C(O)=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
289n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342586
PNG
(3-methyl-1-[2-(tetrahydrofuran-3-ylmethoxy)phenyl]...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCC1CCOC1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
315n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342596
PNG
(1-(5-amino-2-phenoxyphenyl)-3-methyl-2,5,6,7-tetra...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(N)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
365n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342628
PNG
(N-{3-[3-methyl-4-oxo-6-(propan-2-yl)-4,5,6,7-tetra...)
Show SMILES CC(C)C1Cc2c([nH]c(C)c2C(=O)C1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
375n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342622
PNG
(3,6-dimethyl-1-(2-phenoxyphenyl)-2,5,6,7-tetrahydr...)
Show SMILES CC1Cc2c([nH]c(C)c2C(=O)C1)-c1ccccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
382n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342621
PNG
(N-[3-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-2H-...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1cccc(NS(C)(=O)=O)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
409n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342630
PNG
(1-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(ccc1OCC1CC1)S(C)(=O)=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
461n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342519
PNG
(3-methyl-1-(2-phenoxyphenyl)-2,5,6,7-tetrahydro-4H...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
504n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342612
PNG
(N-ethyl-3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-is...)
Show SMILES CCNC(=O)c1ccc(Oc2ccccc2)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
511n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342615
PNG
(1-(1,3-benzodioxol-5-yl)-3,6,6-trimethyl-2,5,6,7-t...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1ccc2OCOc2c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
513n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342594
PNG
(3-methyl-1-[2-(pyridin-3-ylmethoxy)phenyl]-2,5,6,7...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1cccnc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
526n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342607
PNG
(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Show SMILES CC(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
551n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342600
PNG
(1-[5-amino-2-(phenylsulfanyl)phenyl]-3-methyl-2,5,...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(N)ccc1Sc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
568n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342599
PNG
(N-[3-(2,3-dimethyl-4-oxo-4,5,6,7-tetrahydro-2H-iso...)
Show SMILES CC(=O)Nc1ccc(Oc2ccccc2)c(c1)-c1c2CCCC(=O)c2c(C)n1C
Show InChI InChI=1S/C24H24N2O3/c1-15-23-19(10-7-11-21(23)28)24(26(15)3)20-14-17(25-16(2)27)12-13-22(20)29-18-8-5-4-6-9-18/h4-6,8-9,12-14H,7,10-11H2,1-3H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
569n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342621
PNG
(N-[3-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-2H-...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1cccc(NS(C)(=O)=O)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
576n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342613
PNG
(3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(ccc1Oc1ccccc1)C(=O)NCC1CCCO1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
653n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342588
PNG
(3-methyl-1-[2-(tetrahydrofuran-2-ylmethoxy)phenyl]...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCC1CCCO1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
765n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342620
PNG
(3,6,6-trimethyl-1-(2-phenoxyphenyl)-2,5,6,7-tetrah...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1ccccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
786n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342563
PNG
(3-methyl-1-(3,4,5-trimethoxyphenyl)-2,5,6,7-tetrah...)
Show SMILES COc1cc(cc(OC)c1OC)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
805n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342628
PNG
(N-{3-[3-methyl-4-oxo-6-(propan-2-yl)-4,5,6,7-tetra...)
Show SMILES CC(C)C1Cc2c([nH]c(C)c2C(=O)C1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
926n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342610
PNG
(US9776990, Example 53 | methyl 3-(3-methyl-4-oxo-4...)
Show SMILES COC(=O)c1ccc(Oc2ccccc2)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
927n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342615
PNG
(1-(1,3-benzodioxol-5-yl)-3,6,6-trimethyl-2,5,6,7-t...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1ccc2OCOc2c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
932n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342576
PNG
(3-methyl-1-(naphthalen-1-yl)-2,5,6,7-tetrahydro-4H...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cccc2ccccc12
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
943n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342575
PNG
(1-[2-(benzyloxy)phenyl]-3-methyl-2,5,6,7-tetrahydr...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
943n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342608
PNG
(N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(NC(=O)c2ccc[nH]2)ccc1Oc1ccc(F)cc1F
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
943n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342565
PNG
(3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Show SMILES NC(=O)c1cccc(c1)-c1[nH]cc2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
961n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342620
PNG
(3,6,6-trimethyl-1-(2-phenoxyphenyl)-2,5,6,7-tetrah...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1ccccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.03E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342590
PNG
(3-methyl-1-{2-[2-(morpholin-4-yl)ethoxy]phenyl}-2,...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCCN1CCOCC1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.04E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342614
PNG
(3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(ccc1Oc1ccccc1)C(=O)Nc1nccs1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.07E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342599
PNG
(N-[3-(2,3-dimethyl-4-oxo-4,5,6,7-tetrahydro-2H-iso...)
Show SMILES CC(=O)Nc1ccc(Oc2ccccc2)c(c1)-c1c2CCCC(=O)c2c(C)n1C
Show InChI InChI=1S/C24H24N2O3/c1-15-23-19(10-7-11-21(23)28)24(26(15)3)20-14-17(25-16(2)27)12-13-22(20)29-18-8-5-4-6-9-18/h4-6,8-9,12-14H,7,10-11H2,1-3H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.09E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342572
PNG
(1-(2-chlorophenyl)-3-methyl-2,5,6,7-tetrahydro-4H-...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1Cl
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.14E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342627
PNG
(3-methyl-1-(2-phenoxyphenyl)-6-(propan-2-yl)-2,5,6...)
Show SMILES CC(C)C1Cc2c([nH]c(C)c2C(=O)C1)-c1ccccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.20E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342581
PNG
(3-methyl-1-[2-(phenoxymethyl)phenyl]-2,5,6,7-tetra...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1COc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.20E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342587
PNG
(1-[2-(cyclopentylmethoxy)phenyl]-3-methyl-2,5,6,7-...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCC1CCCC1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.25E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342591
PNG
(3-methyl-1-[2-(pyridin-2-ylmethoxy)phenyl]-2,5,6,7...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1ccccn1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.35E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342561
PNG
(4-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc(cc1)S(N)(=O)=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.40E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342564
PNG
(3-methyl-1-[4-(methylsulfonyl)phenyl]-2,5,6,7-tetr...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1[nH]cc2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.43E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342619
PNG
(1-[2-(benzyloxy)phenyl]-3,6,6-trimethyl-2,5,6,7-te...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1ccccc1OCc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.50E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342618
PNG
(3,6,6-trimethyl-1-[2-(morpholin-4-yl)phenyl]-2,5,6...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1ccccc1N1CCOCC1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.68E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342619
PNG
(1-[2-(benzyloxy)phenyl]-3,6,6-trimethyl-2,5,6,7-te...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1ccccc1OCc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.75E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342577
PNG
(1-(3-methoxyphenyl)-3-methyl-2,5,6,7-tetrahydro-4H...)
Show SMILES COc1cccc(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.77E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342566
PNG
(1-(1H-indol-4-yl)-3-methyl-2,5,6,7-tetrahydro-4H-i...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cccc2[nH]ccc12
Show InChI InChI=1S/C17H14N2O/c1-10-16-13(5-3-7-15(16)20)17(19-10)12-4-2-6-14-11(12)8-9-18-14/h2,4,6,8-9H,3,5,7H2,1H3/b17-12-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.79E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342600
PNG
(1-[5-amino-2-(phenylsulfanyl)phenyl]-3-methyl-2,5,...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(N)ccc1Sc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.82E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342578
PNG
(1-(1H-benzimidazol-4-yl)-3-methyl-2,5,6,7-tetrahyd...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cccc2[nH]cnc12
Show InChI InChI=1S/C16H13N3O/c1-9-14-10(4-3-7-13(14)20)15(19-9)11-5-2-6-12-16(11)18-8-17-12/h2,5-6,8H,3-4,7H2,1H3/b15-11+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.86E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342567
PNG
(1-(4-methoxyphenyl)-3-methyl-2,5,6,7-tetrahydro-4H...)
Show SMILES COc1ccc(cc1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.88E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342589
PNG
(3-methyl-1-[2-(tetrahydro-2H-pyran-4-ylmethoxy)phe...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCC1CCOCC1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.94E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342575
PNG
(1-[2-(benzyloxy)phenyl]-3-methyl-2,5,6,7-tetrahydr...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.03E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342561
PNG
(4-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc(cc1)S(N)(=O)=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.03E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342626
PNG
(N-{3-[3-methyl-6-(2-methylpropyl)-4-oxo-4,5,6,7-te...)
Show SMILES CC(C)CC1Cc2c([nH]c(C)c2C(=O)C1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.07E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342618
PNG
(3,6,6-trimethyl-1-[2-(morpholin-4-yl)phenyl]-2,5,6...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1ccccc1N1CCOCC1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.20E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342627
PNG
(3-methyl-1-(2-phenoxyphenyl)-6-(propan-2-yl)-2,5,6...)
Show SMILES CC(C)C1Cc2c([nH]c(C)c2C(=O)C1)-c1ccccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.22E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342581
PNG
(3-methyl-1-[2-(phenoxymethyl)phenyl]-2,5,6,7-tetra...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1COc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.30E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342579
PNG
(1-(1H-indol-7-yl)-3-methyl-2,5,6,7-tetrahydro-4H-i...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cccc2cc[nH]c12
Show InChI InChI=1S/C17H14N2O/c1-10-15-12(5-3-7-14(15)20)17(19-10)13-6-2-4-11-8-9-18-16(11)13/h2,4,6,8-9H,3,5,7H2,1H3/b17-13+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.47E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342560
PNG
(3-methyl-1-(4-methylphenyl)-2,5,6,7-tetrahydro-4H-...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc(C)cc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.49E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342616
PNG
(3,6,6-trimethyl-1-phenyl-2,5,6,7-tetrahydro-4H-iso...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.52E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342591
PNG
(3-methyl-1-[2-(pyridin-2-ylmethoxy)phenyl]-2,5,6,7...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1ccccn1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.62E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342562
PNG
(1-(2-methoxyphenyl)-3-methyl-2,5,6,7-tetrahydro-4H...)
Show SMILES COc1ccccc1-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.70E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342617
PNG
(1-(2,5-dimethylphenyl)-3,6,6-trimethyl-2,5,6,7-tet...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1cc(C)ccc1C
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.70E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342584
PNG
(1-[2-(furan-2-yl)phenyl]-3-methyl-2,5,6,7-tetrahyd...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1-c1ccco1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.76E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342568
PNG
(1-(3,4-dimethylphenyl)-3-methyl-2,5,6,7-tetrahydro...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc(C)c(C)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.86E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342586
PNG
(3-methyl-1-[2-(tetrahydrofuran-3-ylmethoxy)phenyl]...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCC1CCOC1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.92E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342493
PNG
(3-methyl-1-phenyl-2,5,6,7-tetrahydro-4H-isoindol-4...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
3.07E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342565
PNG
(3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Show SMILES NC(=O)c1cccc(c1)-c1[nH]cc2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
3.10E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342616
PNG
(3,6,6-trimethyl-1-phenyl-2,5,6,7-tetrahydro-4H-iso...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
3.23E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342617
PNG
(1-(2,5-dimethylphenyl)-3,6,6-trimethyl-2,5,6,7-tet...)
Show SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1cc(C)ccc1C
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
3.37E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342625
PNG
(3-methyl-6-(2-methylpropyl)-1-(2-phenoxyphenyl)-2,...)
Show SMILES CC(C)CC1Cc2c([nH]c(C)c2C(=O)C1)-c1ccccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
3.62E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342610
PNG
(US9776990, Example 53 | methyl 3-(3-methyl-4-oxo-4...)
Show SMILES COC(=O)c1ccc(Oc2ccccc2)c(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
3.67E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342493
PNG
(3-methyl-1-phenyl-2,5,6,7-tetrahydro-4H-isoindol-4...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
3.68E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342559
PNG
(1-(2-aminophenyl)-3-methyl-2,5,6,7-tetrahydro-4H-i...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1N
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
3.73E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342573
PNG
(1-(1,3-benzodioxol-5-yl)-3-methyl-2,5,6,7-tetrahyd...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc2OCOc2c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
3.77E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342564
PNG
(3-methyl-1-[4-(methylsulfonyl)phenyl]-2,5,6,7-tetr...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1[nH]cc2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
3.82E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342566
PNG
(1-(1H-indol-4-yl)-3-methyl-2,5,6,7-tetrahydro-4H-i...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cccc2[nH]ccc12
Show InChI InChI=1S/C17H14N2O/c1-10-16-13(5-3-7-15(16)20)17(19-10)12-4-2-6-14-11(12)8-9-18-14/h2,4,6,8-9H,3,5,7H2,1H3/b17-12-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
4.06E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342594
PNG
(3-methyl-1-[2-(pyridin-3-ylmethoxy)phenyl]-2,5,6,7...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1cccnc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
4.14E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342582
PNG
(3-methyl-1-{2-[(2-methylphenoxy)methyl]phenyl}-2,5...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1COc1ccccc1C
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
4.24E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342577
PNG
(1-(3-methoxyphenyl)-3-methyl-2,5,6,7-tetrahydro-4H...)
Show SMILES COc1cccc(c1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
4.49E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342588
PNG
(3-methyl-1-[2-(tetrahydrofuran-2-ylmethoxy)phenyl]...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCC1CCCO1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
4.68E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342587
PNG
(1-[2-(cyclopentylmethoxy)phenyl]-3-methyl-2,5,6,7-...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCC1CCCC1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
4.78E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342595
PNG
(1-[2-(1H-indazol-5-ylmethoxy)phenyl]-3-methyl-2,5,...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1ccc2[nH]ncc2c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
4.86E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342595
PNG
(1-[2-(1H-indazol-5-ylmethoxy)phenyl]-3-methyl-2,5,...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1ccc2[nH]ncc2c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
4.88E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342585
PNG
(1-(2-hydroxyphenyl)-3-methyl-2,5,6,7-tetrahydro-4H...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
5.31E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342567
PNG
(1-(4-methoxyphenyl)-3-methyl-2,5,6,7-tetrahydro-4H...)
Show SMILES COc1ccc(cc1)-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
5.46E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342574
PNG
(1-(3,5-dimethylphenyl)-3-methyl-2,5,6,7-tetrahydro...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(C)cc(C)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
5.51E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342578
PNG
(1-(1H-benzimidazol-4-yl)-3-methyl-2,5,6,7-tetrahyd...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cccc2[nH]cnc12
Show InChI InChI=1S/C16H13N3O/c1-9-14-10(4-3-7-13(14)20)15(19-9)11-5-2-6-12-16(11)18-8-17-12/h2,5-6,8H,3-4,7H2,1H3/b15-11+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
5.92E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342583
PNG
(2-[2-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1CN1C(=O)c2ccccc2C1=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
6.22E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342584
PNG
(1-[2-(furan-2-yl)phenyl]-3-methyl-2,5,6,7-tetrahyd...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1-c1ccco1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
6.58E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342629
PNG
(N-[3-(3-methyl-4-oxo-6-phenyl-4,5,6,7-tetrahydro-2...)
Show SMILES Cc1[nH]c(c2CC(CC(=O)c12)c1ccccc1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
7.28E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342569
PNG
(1-(4-chlorophenyl)-3-methyl-2,5,6,7-tetrahydro-4H-...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc(Cl)cc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
7.29E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342590
PNG
(3-methyl-1-{2-[2-(morpholin-4-yl)ethoxy]phenyl}-2,...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCCN1CCOCC1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
8.16E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342579
PNG
(1-(1H-indol-7-yl)-3-methyl-2,5,6,7-tetrahydro-4H-i...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cccc2cc[nH]c12
Show InChI InChI=1S/C17H14N2O/c1-10-15-12(5-3-7-14(15)20)17(19-10)13-6-2-4-11-8-9-18-16(11)13/h2,4,6,8-9H,3,5,7H2,1H3/b17-13+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
8.21E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342573
PNG
(1-(1,3-benzodioxol-5-yl)-3-methyl-2,5,6,7-tetrahyd...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc2OCOc2c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
8.42E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342593
PNG
(1-[2-(1-benzothiophen-7-ylmethoxy)phenyl]-3-methyl...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1cccc2ccsc12
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
8.83E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342580
PNG
(3-methyl-1-(2-{[3-(trifluoromethyl)phenoxy]methyl}...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1COc1cccc(c1)C(F)(F)F
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
8.92E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342570
PNG
(1-[3-(benzyloxy)phenyl]-3-methyl-2,5,6,7-tetrahydr...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cccc(OCc2ccccc2)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
9.06E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342580
PNG
(3-methyl-1-(2-{[3-(trifluoromethyl)phenoxy]methyl}...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1COc1cccc(c1)C(F)(F)F
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
9.09E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342592
PNG
(3-methyl-1-[2-(quinolin-8-ylmethoxy)phenyl]-2,5,6,...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1cccc2cccnc12
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
9.14E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...


US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342593
PNG
(1-[2-(1-benzothiophen-7-ylmethoxy)phenyl]-3-methyl...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1cccc2ccsc12
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
9.73E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342562
PNG
(1-(2-methoxyphenyl)-3-methyl-2,5,6,7-tetrahydro-4H...)
Show SMILES COc1ccccc1-c1[nH]c(C)c2c1CCCC2=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
9.97E+3n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342568
PNG
(1-(3,4-dimethylphenyl)-3-methyl-2,5,6,7-tetrahydro...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc(C)c(C)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.04E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342583
PNG
(2-[2-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1CN1C(=O)c2ccccc2C1=O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.04E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342592
PNG
(3-methyl-1-[2-(quinolin-8-ylmethoxy)phenyl]-2,5,6,...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1OCc1cccc2cccnc12
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.10E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342559
PNG
(1-(2-aminophenyl)-3-methyl-2,5,6,7-tetrahydro-4H-i...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1N
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.50E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342585
PNG
(1-(2-hydroxyphenyl)-3-methyl-2,5,6,7-tetrahydro-4H...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1O
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.51E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342582
PNG
(3-methyl-1-{2-[(2-methylphenoxy)methyl]phenyl}-2,5...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1COc1ccccc1C
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.51E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342560
PNG
(3-methyl-1-(4-methylphenyl)-2,5,6,7-tetrahydro-4H-...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc(C)cc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.59E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342574
PNG
(1-(3,5-dimethylphenyl)-3-methyl-2,5,6,7-tetrahydro...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(C)cc(C)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.75E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342576
PNG
(3-methyl-1-(naphthalen-1-yl)-2,5,6,7-tetrahydro-4H...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cccc2ccccc12
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
1.97E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342625
PNG
(3-methyl-6-(2-methylpropyl)-1-(2-phenoxyphenyl)-2,...)
Show SMILES CC(C)CC1Cc2c([nH]c(C)c2C(=O)C1)-c1ccccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.22E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342570
PNG
(1-[3-(benzyloxy)phenyl]-3-methyl-2,5,6,7-tetrahydr...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cccc(OCc2ccccc2)c1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.22E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342569
PNG
(1-(4-chlorophenyl)-3-methyl-2,5,6,7-tetrahydro-4H-...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc(Cl)cc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.22E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342614
PNG
(3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(ccc1Oc1ccccc1)C(=O)Nc1nccs1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.22E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342572
PNG
(1-(2-chlorophenyl)-3-methyl-2,5,6,7-tetrahydro-4H-...)
Show SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccccc1Cl
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.22E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM342629
PNG
(N-[3-(3-methyl-4-oxo-6-phenyl-4,5,6,7-tetrahydro-2...)
Show SMILES Cc1[nH]c(c2CC(CC(=O)c12)c1ccccc1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
UniChem
US Patent
2.22E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

US Patent




US Patent US9776990 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%